May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

DHFR Return to Main Page

Instructions
  • Use the menu to the right to browse the coupling matrix.

Coupling matrix for [L:0074] and [S:0091]
- A F I L V M W Y D E K R H N Q S T G P C
A 0.2 0.3 -0.1 -0.2 -0.1 -0.1 0 -0.1 0 -0.1 0 0 -0.1 -0.1 0.4 -0.1 -0.1 0 0 -0.2
F -0.4 -0.3 0.3 0.1 0.8 0.4 0 -0.3 0 -0.1 0.3 -0.1 0.2 0.5 -0.1 -0.4 -0.2 -0.1 -0.1 0.5
I 0.8 -0.4 0 0.2 0.8 0.7 0 0.4 -0.2 0.1 0 0 0 -0.2 -0.4 -0.2 0.2 -0.2 -0.4 0.4
L -0.1 0.8 0.1 -0.1 0.3 0.3 -0.1 -0.1 -0.1 -0.4 0.3 -0.3 0.5 -0.6 -0.3 0.2 -0.1 -0.2 0.1 0
V 1.2 -0.3 0.2 -0.2 0 -0.5 -0.2 0.3 -0.2 0.6 -0.2 0.3 -0.6 0.1 -0.1 0.8 0.2 -0.1 0.2 0.5
M -0.1 0.1 -0.1 -0.2 0 -0.1 0 0.4 0 0 0 0 0 -0.1 0 -0.1 0.4 0 0 0
W -0.1 0.7 -0.1 0.2 -0.2 -0.1 0 -0.1 0 0 0 0 0 0 0 -0.1 -0.1 0 0 -0.1
Y -0.6 -0.1 0.9 0.2 0.7 -0.4 -0.1 0 -0.1 0.1 -0.2 -0.2 -0.3 0.9 0.5 -0.2 0 0 -0.1 -0.3
D 0 -0.1 0 0 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
E 0 -0.1 0 0 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
K 0 -0.1 0 0 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
R -0.1 -0.2 -0.1 0.3 -0.2 0 0 -0.1 0 0 0 0 0 0 0 -0.1 0 0 0 -0.1
H -0.2 -0.3 -0.1 -0.1 -0.3 -0.1 0 -0.1 0 0 0 0 0.4 -0.1 0 0.3 0 0 0 -0.2
N 0 -0.1 0 0 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Q 0 -0.1 0 0 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
S 0 -0.1 0 0 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
T -0.1 0.1 -0.1 0.2 0 -0.1 0 -0.1 0 0 0 0 0 -0.1 0 -0.1 0 0 0 0.2
G 0 -0.1 0 0 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
P 0 -0.1 0 0 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
C 0 0.7 -0.2 0.1 -0.6 -0.1 0 -0.1 0 -0.1 -0.1 0.4 -0.1 -0.1 -0.1 0.2 -0.1 0.3 0 -0.1

Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0074 -0.1 1.1 2.9 1.8 2.5 -0.2 -0.3 1.5 -0.9 -0.9 -0.9 -0.6 -0.2 -0.9 -0.9 -0.9 -0.3 -0.9 -0.9 0.1
0091 0.1 1.4 0.7 0.6 1.1 -0.3 -1.1 0.1 -1.2 -0.1 -0.4 -0.4 -0.2 0.1 -0.4 0.5 0.2 -0.6 -0.9 0.6
Select residue pair below:
i_j Score Prob
0052_0074 1.322 0.99
0074_0091 0.957 0.87
Local Interactions:
i_j Score Prob
0072_0074 0.676 0.51
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M V G S L ...

Page generated in 0.0187 seconds.