May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
DHFR Return to Main Page
Instructions
  • Use the menu to the right to browse the coupling matrix.
Coupling matrix for [I:0072] and [L:0074]
- A F I L V M W Y D E K R H N Q S T G P C
A 0 -0.2 0.2 0 -0.2 0 0 0.1 0 0 0 0 0 0 0 0 0 0 0 0.3
F 0.4 -0.2 0.3 -0.3 -0.1 0 0 0.1 0 0 0 0 0 0 0 0 0 0 0 -0.1
I -0.3 0.5 -0.4 -0.1 0.6 0.4 -0.1 -0.2 -0.1 -0.1 -0.1 -0.2 0.2 -0.1 -0.1 -0.1 0.1 -0.1 -0.1 0.2
L -0.2 -0.5 0.3 0.5 1 -0.2 -0.1 -0.3 -0.1 -0.1 -0.1 -0.1 -0.2 -0.1 -0.1 -0.1 0.4 -0.1 -0.1 -0.1
V -0.2 0.1 -0.1 -0.3 0.6 0.2 -0.1 -0.2 0 0 0 0.3 0.3 0 0 0 -0.1 0 0 0.2
M -0.1 0.1 -0.1 0.1 -0.2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.3
W 0 0 -0.5 -0.1 0.3 0 0 -0.1 0 0 0 0 0 0 0 0 0 0 0 0
Y -0.1 -0.2 -0.2 -0.1 0.7 0 0 -0.2 0 0 0 0 0.4 0 0 0 0 0 0 -0.1
D -0.1 0.1 0.1 0 -0.9 -0.1 0.3 0.4 0 0 0 -0.1 0.2 0 0 0 -0.1 0 0 0.1
E 0.2 0.7 0.1 0.2 -0.3 -0.1 0.2 0.4 0 0 0 -0.1 -0.1 0 0 0 -0.1 0 0 -0.3
K 0.4 -0.5 0.4 0.3 0.1 0.2 -0.2 0.7 -0.1 -0.1 -0.1 -0.1 -0.2 -0.1 -0.1 -0.1 0.3 -0.1 -0.1 -0.3
R 0.3 0 0.6 0.6 0.3 -0.2 -0.1 -0.7 0 0 0 -0.1 -0.1 0 0 0 -0.1 0 0 -0.3
H -0.1 0.6 0.2 -0.3 -0.1 -0.1 -0.1 0.3 0 0 0 0 -0.1 0 0 0 -0.1 0 0 -0.2
N 0 -0.1 -0.1 0 -0.3 0 0 0.4 0 0 0 0.4 0 0 0 0 0 0 0 -0.1
Q -0.1 0.2 0.8 0.2 -0.2 -0.1 0.2 -0.1 0 0 0 -0.1 -0.1 0 0 0 -0.1 0 0 -0.2
S 0 -0.1 -0.1 -0.2 -0.1 0 0 0.3 0 0 0 0 0 0 0 0 0 0 0 0
T 0.1 -0.5 0.8 0.1 0.4 0 0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.3 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 0.4
G 0 0.3 -0.5 0.3 -0.2 0 0 -0.1 0 0 0 0 0 0 0 0 0 0 0 0
P -0.1 0.5 -0.2 0.1 -0.6 0 0 0.2 0 0 0 0 0 0 0 0 0 0 0 0.1
C 0 -0.1 -0.4 -0.1 0.2 0 0 -0.1 0 0 0 0 0 0 0 0 0 0 0 0
Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0072 0.1 -0.6 1.1 0 0.6 -0.1 -0.8 0 -0.4 0.6 0.9 0 0 0.2 0.6 -0.7 0.7 -0.7 -0.3 -0.9
0074 -0.1 1.1 2.9 1.8 2.5 -0.2 -0.3 1.5 -0.9 -0.9 -0.9 -0.6 -0.2 -0.9 -0.9 -0.9 -0.3 -0.9 -0.9 0.1
Select residue pair below:
i_j Score Prob
0052_0074 1.322 0.99
0074_0091 0.957 0.87
Local Interactions:
i_j Score Prob
0072_0074 0.676 0.51
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M V G S L ...
Page generated in 0.0129 seconds.