OPENSEQ.org -1516281329- GREMLIN Submission

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mep50

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Coupling matrix for [P:0215] and [F:0230]

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
A	0	-0.5	0.6	0.1	0.5	0.4	0.1	-0.6	0.1	0.3	0.1	-0.3	0.2	0.2	-0.2	0.3	0.2	-0.4	-0.4	-0.7
F	0.5	-0.4	-0.7	0.2	-0.3	-0.3	-0.1	-0.3	0	-0.1	0.1	-0.3	-0.2	-0.1	-0.2	-0.2	0.1	1.7	0.6	0.1
I	0.2	0.6	0.4	0.3	0.1	0.2	0	0.4	-0.3	-0.5	0	0.2	0.1	0.1	-0.4	0.2	0.7	-0.3	-0.8	0
L	0.2	0.1	0.3	-0.2	0.3	0.5	0	0.2	-0.1	-0.3	-0.3	-0.4	0	0.2	-0.2	-0.3	0.3	0.2	0	0.4
V	0.5	0.3	-0.2	-0.1	0	-0.2	-0.1	0.5	0.2	-0.3	-0.3	0	-0.3	-0.6	-0.1	0.9	0.9	-0.2	-0.3	0.2
M	0.4	0.5	-0.2	-0.4	0.3	0.1	-0.1	0.1	-0.1	-0.1	-0.1	-0.2	-0.1	0.1	0.1	-0.5	0.4	-0.2	-0.3	0.3
W	0.2	-0.4	0.3	0.9	0.6	-0.2	0	0.1	-0.1	-0.1	-0.1	0.1	-0.1	0.1	-0.1	0	-1.1	-0.7	-0.2	0.3
Y	0.4	-0.6	-0.2	-0.1	0.2	-0.3	0	0.2	0.2	-0.1	-0.1	-0.2	-0.1	-0.2	-0.1	-0.9	-0.4	0.8	1.4	0.3
D	-0.1	0.1	-0.1	-0.3	0.2	-0.1	0.2	0.2	0	0	0	-0.1	0	-0.1	0	-0.2	-0.3	-0.4	-0.2	-0.6
E	-0.5	0.5	-0.2	0.3	-0.1	0.1	0	0.1	0	0	0	-0.1	0	0.3	0	-0.5	-0.8	0.2	-0.1	0.5
K	-0.4	-0.1	0.2	0.7	-0.4	-0.1	0	-0.1	0.2	0	0	-0.1	0	-0.1	0	-0.2	0.1	0.2	-0.1	-0.3
R	-0.7	0.2	-0.1	-0.4	0.2	-0.1	0	0.1	-0.1	0.2	0	0.4	0.2	-0.1	-0.1	-0.2	-1	-0.2	1.3	-0.1
H	-0.5	0.2	-0.2	0.7	-0.3	-0.1	0	0.2	0	0	0	0.2	0	-0.1	0	0.1	0.9	-0.7	0	-0.4
N	0.7	-0.3	0.2	-0.4	-0.3	-0.2	0	-0.2	0.2	0	0	-0.1	0.2	-0.1	0.2	-0.6	-0.1	1.2	0.1	-0.2
Q	-0.8	0.2	-0.6	-0.6	-0.4	-0.2	-0.1	-0.2	-0.1	0	-0.1	-0.1	-0.1	-0.2	-0.1	2	0.2	0.1	-0.1	0.4
S	-0.1	0.4	-0.1	0.1	-0.1	0.1	-0.1	-0.3	0.1	-0.1	0.4	-0.4	0.1	-0.1	0.1	0.1	-0.4	0.3	0	0
T	0.1	-0.2	0.4	0.1	0.1	0.5	-0.1	-0.3	-0.1	0.1	-0.1	-0.3	0.1	0.4	0.7	0.1	0.8	-0.6	-0.6	-0.7
G	0.3	-0.6	-0.1	-0.6	0.2	0.1	-0.1	-0.4	0	0	-0.1	1.1	-0.1	0	-0.1	-0.4	0.5	0.1	-0.3	0.5
P	0.1	0.2	0.7	-0.2	0	-0.1	-0.1	0.5	-0.3	-0.1	0.1	0.1	0.1	0.2	-0.2	0	0	-0.1	-0.6	-0.4
C	0.5	0	0.2	0.8	0.3	0.1	-0.1	-0.2	-0.1	-0.1	-0.1	0.3	-0.1	-0.3	0.2	-0.1	-0.3	-0.8	0.1	0.5

Conservation matrix (aka PSSM)

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
0215	0.8	0.4	1.9	1.4	1.7	0.2	-0.8	0.1	-0.8	-1.1	-0.9	-0.4	-1.4	-0.4	-1.6	0.3	0.3	0.2	0.6	-0.1
0230	0.9	0.3	0.8	1.2	1	0	-0.9	-0.3	-0.5	-0.8	-0.8	0	-0.6	-0.4	-0.4	0	0.7	0	-0.5	0.1

Select residue pair below:

i_j	Score	Prob
0186_0215	1.620	1.00
0211_0215	0.825	0.78
0215_0230	0.764	0.71

Local Interactions:

i_j	Score	Prob
0214_0215	0.695	0.60
0213_0215	0.536	0.33
0215_0216	0.533	0.33

See all coupling residues
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