OPENSEQ.org -1516272175- GREMLIN Submission

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PRMT5 292-637

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Coupling matrix for [H:0335] and [P:0337]

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
A	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.1	0	0.4	-0.1	0
F	0.2	0	0	0	-0.1	0	0	0	0	-0.1	0.3	0	0	0	0	0.3	0	0	-0.2	0
I	-0.1	0	0	0	0	0	0	0	0.4	-0.1	0	0	0	0	0.4	-0.2	0	0	-0.1	0
L	-0.1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.1	0	0	0.5	0
V	0	0	0	0	0	0	0	0	0	0	0	0	0	0.2	0	0	0	0	-0.1	0
M	0.2	0	0	0	-0.1	0	0	0	0	0.2	-0.1	-0.1	0	0	0	-0.2	0	0	0.4	0
W	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.1	0	0	0	0
Y	-0.2	0	-0.1	-0.1	-0.1	0	0	-0.1	0	-0.1	0.5	0.3	0.3	0	-0.1	0.2	-0.1	0	-0.3	0.4
D	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.1	0	0	0	0
E	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.1	0	0	0	0
K	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.1	0	0	0	0
R	0.2	0	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.1	0	0	-0.1	0
H	0.5	-0.1	0.5	0.3	0.2	-0.2	0	0.2	-0.3	0.1	-0.4	-0.3	0	-0.2	-0.1	0.3	0.4	-0.3	0.8	-0.3
N	-0.1	0	0	0	0.3	0	0	0	0	0	0	0	0	0	0	0.2	-0.1	0	-0.1	0
Q	-0.1	-0.1	-0.2	0.1	0.4	0	-0.1	-0.1	-0.1	0.4	0.3	0.3	-0.2	-0.1	-0.1	0	0	-0.1	0.1	-0.2
S	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.2	0	0	-0.1	0
T	0	0	0	0	0	0	0	0	0	0	0.1	0	0.1	0	0	-0.1	0	0	-0.1	0
G	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.2	0	0	0	0
P	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.1	0	0	0	0
C	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.3	0	0	-0.1	0

Conservation matrix (aka PSSM)

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
0335	-0.1	0.2	0	0	-0.2	0.1	-0.4	0.5	-0.4	-0.4	-0.1	-0.2	1	0	0.7	-0.2	-0.2	-0.1	-0.4	0
0337	0.5	-0.5	0	0.2	0.5	-0.6	-0.4	-0.3	-0.4	0.2	0.4	-0.1	-0.1	-0.4	-0.2	0.8	-0.1	-0.3	0.6	-0.4

Select residue pair below:

i_j	Score	Prob
0332_0335	1.168	0.76
0327_0335	0.818	0.38
0019_0335	0.818	0.38
0335_0341	0.778	0.33
0016_0335	0.759	0.31

Local Interactions:

i_j	Score	Prob
0335_0336	1.105	0.70
0335_0337	0.905	0.48
0334_0335	0.862	0.43
0333_0335	0.771	0.32

See all coupling residues
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