OPENSEQ.org -1516272175- GREMLIN Submission

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PRMT5 292-637

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Coupling matrix for [Y:0263] and [P:0278]

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
A	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.1	0	0	0.1	0
F	-0.2	-0.1	0.1	-0.1	-0.3	-0.1	0	-0.1	-0.1	-0.2	-0.1	-0.1	-0.1	0.2	0.2	0.5	-0.1	-0.1	0.8	-0.1
I	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.2	0
L	0	0	0	0	-0.1	0	0	0	0	-0.1	0.4	0	0	0	0	-0.1	0	0	0.1	0
V	0	0	0	0	0	0	0	0	0	-0.1	0	0.4	0	0	0	-0.1	0	0	-0.3	0
M	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.2	0
W	-0.1	0.6	0.2	-0.1	0	-0.1	-0.1	-0.1	0.3	0	0	-0.3	0.1	-0.3	-0.1	0.1	0.3	-0.2	1	-0.2
Y	-0.4	-0.2	0.2	0	0.4	0.2	-0.1	-0.1	0.1	-0.5	0.3	0.2	-0.2	0.4	0	-0.8	-0.1	0.4	0.9	-0.1
D	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.2	0
E	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.2	0
K	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.2	0
R	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.2	0
H	0.7	-0.1	-0.1	-0.1	-0.2	0	0	-0.1	-0.1	-0.2	-0.1	-0.1	0.4	-0.1	-0.1	0.9	0	-0.1	-0.3	-0.1
N	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.4	0	0	-0.4	0
Q	0	0	0	0	0	0	0	0	0	0.5	0	0	0	0	0	0	0	0	-0.4	0
S	0.2	-0.1	-0.1	0.5	0.6	0	0	-0.1	-0.1	-0.1	-0.1	-0.1	0	-0.1	0	-0.3	-0.1	0	-0.5	0.3
T	0	0	0	0.1	0	0	0	0	0	-0.1	0	0	0	0	0	-0.1	0	0	0.4	0
G	0	0	0	0	0	0	0	0.4	0	0.6	0	0	0	0	0	-0.2	0	0	-0.4	0
P	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.1	0
C	0	0	0	0	0	0	0	0	0	0.3	0	0	0	0	0	0.1	0	0	-0.1	0

Conservation matrix (aka PSSM)

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
0263	-0.2	1	-0.6	0	-0.1	-0.6	1.5	1.1	-0.6	-0.6	-0.6	-0.6	0.7	-0.3	-0.3	0.6	0.1	0	-0.3	0
0278	0.2	-0.1	0.2	0.1	0.4	-0.3	-0.5	-0.2	-0.1	0.4	0.2	0	-0.1	0.1	-0.3	0.6	-0.2	-0.2	-0.5	-0.3

Select residue pair below:

i_j	Score	Prob
0275_0278	1.807	0.98
0264_0278	1.077	0.67
0278_0290	1.062	0.66
0263_0278	0.914	0.49
0080_0278	0.815	0.37
0153_0278	0.755	0.31

Local Interactions:

i_j	Score	Prob
0276_0278	0.986	0.57

See all coupling residues
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