OPENSEQ.org -1516272175- GREMLIN Submission

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PRMT5 292-637

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Coupling matrix for [L:0215] and [F:0218]

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
A	0.2	0.1	-0.1	-0.1	-0.1	-0.1	0.4	-0.3	-0.1	0.3	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	0	-0.1	0	-0.1
F	-0.3	-0.6	0.1	0.1	1.3	0.5	-0.4	-0.8	-0.1	0	0.6	0.9	-0.5	-0.3	0.1	-0.5	1.1	-0.3	-0.1	0.2
I	1.2	-0.2	-0.6	-0.1	-0.4	0	-0.4	-0.1	-0.1	0.4	-0.5	0.2	-0.6	0.5	0.3	0.6	-0.2	0.9	-0.1	-0.2
L	-0.6	0.4	0.7	0	0.5	0.1	-0.6	-0.1	0	0.3	0	-0.3	0.3	0	-0.3	0	-0.1	-0.5	0.4	1
V	0.4	-0.4	-0.4	-0.6	-0.1	-0.1	-0.2	-0.1	0.6	0.7	1	-0.1	-0.9	0.8	0.5	0.5	-0.3	0.8	-0.2	-0.7
M	0.7	-0.1	-0.5	-0.3	0.2	0.1	0.5	0.1	-0.3	-0.4	0.4	-0.3	0.1	-0.2	-0.2	0.3	-0.2	0.1	-0.1	-0.3
W	-0.1	-0.2	-0.1	-0.1	-0.1	0	0	-0.2	0	-0.1	-0.1	-0.1	0.3	0	0	-0.1	0	0	0	-0.1
Y	0	0.5	0.1	-0.2	-0.3	-0.1	-0.1	-0.2	0.2	-0.2	-0.2	-0.2	-0.3	-0.1	-0.1	0.1	-0.1	0.3	0	0.5
D	-0.1	0.1	-0.1	0.4	-0.1	-0.1	-0.1	-0.3	-0.1	-0.1	-0.1	-0.1	0.3	0	-0.1	-0.1	0	-0.1	0	0.4
E	-0.3	0.4	-0.2	0.3	0.2	-0.1	-0.1	0.2	0.3	-0.2	-0.2	-0.1	0.2	-0.1	-0.1	0.1	-0.1	-0.1	0	-0.2
K	-0.2	-0.3	0.2	-0.1	0.6	-0.1	0.4	0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	0	-0.1	0	-0.1
R	-0.3	0.5	0.5	0.2	-0.3	-0.1	0.6	-0.1	-0.2	-0.2	-0.2	0.6	0.1	-0.1	-0.1	-0.3	-0.1	-0.2	0	-0.2
H	0.2	0.1	-0.1	-0.1	-0.1	-0.1	-0.1	0.4	0.4	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	0	-0.1	0	-0.1
N	-0.3	0	0.1	-0.1	-0.2	-0.1	-0.1	1.5	-0.1	-0.2	-0.2	-0.2	0.2	-0.1	-0.1	0.2	-0.1	0	-0.1	-0.1
Q	-0.1	-0.3	0.2	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.2	0.2	-0.1	-0.2	-0.1	-0.1	0.9	0.4	0.1	0	-0.2
S	0.4	-0.1	-0.2	-0.2	-0.2	-0.1	-0.1	0.2	0.3	-0.2	-0.2	-0.1	0.5	-0.1	0.3	-0.2	-0.1	-0.1	0	0.3
T	0.1	-0.4	0.2	-0.1	-0.2	-0.1	-0.1	-0.1	-0.2	0.5	0.2	-0.2	1	-0.1	-0.1	-0.2	-0.1	-0.2	0	0.2
G	-0.3	-0.3	0.2	-0.1	-0.2	-0.1	0.4	0	-0.1	-0.1	-0.1	0.5	0.2	-0.1	0.4	-0.2	-0.1	-0.1	0	-0.1
P	0	0.7	0.5	0.2	0.7	-0.1	-0.1	0	-0.1	-0.2	-0.2	-0.1	-0.3	-0.1	-0.1	-0.3	-0.1	-0.1	0	-0.2
C	0.2	-0.3	-0.1	0.4	-0.1	-0.1	-0.1	0.1	-0.1	0.3	-0.1	0.3	-0.2	-0.1	-0.1	-0.1	0	-0.1	0	-0.1

Conservation matrix (aka PSSM)

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
0215	-0.6	0.8	1.1	2.1	1.5	0.4	-1	-0.1	-0.8	-0.2	-0.7	-0.1	-0.6	-0.3	-0.2	-0.1	-0.2	-0.5	-0.1	-0.6
0218	0.8	0.8	0.3	-0.1	0.7	-0.3	-0.4	0.9	-0.2	0.1	-0.1	-0.1	0.5	-0.7	-0.6	0.3	-0.6	0	-1.1	0.1

Select residue pair below:

i_j	Score	Prob
0215_0218	0.934	0.51
0184_0218	0.864	0.43

Local Interactions:

i_j	Score	Prob
0218_0220	0.790	0.34

See all coupling residues
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