OPENSEQ.org -1516272175- GREMLIN Submission

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PRMT5 292-637

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Coupling matrix for [R:0201] and [D:0202]

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
A	-0.3	0.2	-0.1	0.2	-0.2	0	0	-0.1	-0.2	-0.1	-0.2	-0.2	-0.1	-0.2	0.6	-0.1	0.2	0.5	-0.2	0
F	-0.1	-0.1	0	-0.1	-0.1	0	0	0	-0.1	0	0.4	0	0	-0.1	0	-0.1	-0.1	-0.1	-0.1	0
I	-0.1	-0.1	0	-0.1	-0.1	0	0	0	-0.1	0	0.1	-0.1	-0.1	-0.1	0	-0.1	-0.1	0.4	-0.1	0
L	0.8	-0.3	-0.1	0.1	-0.3	-0.1	0	-0.1	0.2	-0.1	-0.2	0.2	-0.1	-0.2	-0.2	-0.2	1.1	0.1	0.1	0
V	0.1	-0.2	-0.1	0.4	0.2	-0.1	0	-0.1	0.1	-0.1	0	-0.2	0.1	0.4	0.2	0.1	-0.2	0.1	-0.2	0
M	-0.1	-0.1	0	-0.1	-0.1	0	0	0	-0.1	0	-0.1	-0.1	0	-0.1	0	0	-0.1	0.4	-0.1	0
W	0	-0.1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
Y	0.3	0.1	-0.1	0.1	-0.2	-0.1	0	-0.1	0.2	-0.1	0.2	-0.2	-0.1	0.2	-0.2	-0.1	0.5	0.2	-0.2	-0.1
D	-0.1	0	0.2	0.6	0.3	-0.1	-0.1	-0.1	0.4	-0.2	0.1	0.7	0.2	-0.3	-0.2	-0.3	-0.3	-0.3	0.2	-0.1
E	0.8	0.2	-0.1	-0.2	-0.1	0	0	-0.1	0.1	-0.1	-0.1	-0.1	-0.1	0.2	-0.1	0.3	-0.2	-0.1	-0.2	0
K	-0.3	0.1	-0.1	0.3	-0.3	-0.1	-0.1	-0.1	-0.3	-0.2	-0.1	0.3	1.3	0	-0.2	0.1	-0.3	-0.4	0.8	-0.1
R	-0.2	0.1	-0.2	-0.4	0.1	-0.1	-0.1	0.7	0.5	-0.1	0.1	-0.2	-0.1	0.1	0.3	0.1	-0.3	0.1	0.2	0
H	-0.1	-0.1	0.1	-0.3	0.6	-0.1	-0.1	0.7	-0.1	-0.1	0.6	0.1	-0.2	0.3	-0.2	-0.2	-0.3	-0.3	-0.2	0.4
N	-0.3	0.2	0.2	0	0.1	-0.1	0	-0.1	-0.3	-0.2	0.1	0.2	-0.2	0.5	-0.2	-0.2	0.1	0.4	0	-0.1
Q	-0.1	-0.1	0	-0.1	-0.1	0	0	0	-0.1	0.4	-0.1	-0.1	0	-0.1	0.4	-0.1	0.1	-0.1	-0.1	0
S	-0.2	-0.3	-0.2	-0.4	0	-0.1	-0.1	0	0.4	0.8	0.3	0.2	-0.3	0	-0.2	0	-0.2	0.1	0.3	-0.1
T	0.1	-0.3	-0.1	0.1	-0.2	0	0	-0.1	0.2	-0.1	0.1	-0.2	-0.2	0.1	0.5	-0.2	0.1	0.2	-0.3	0
G	0	1	0.8	0.8	1.1	0.5	0.1	-0.5	-0.3	0.5	-0.7	0.4	0.3	0.1	-0.2	-0.3	-0.3	-0.4	-0.7	-0.2
P	-0.2	0.2	-0.1	-0.2	-0.1	0	0	-0.1	0.2	-0.1	-0.1	-0.2	0.1	-0.1	-0.1	0.6	0.2	-0.2	0.7	0
C	0.2	0.2	0.1	-0.1	-0.1	0	0	0	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	1	-0.1	-0.1	-0.1	0

Conservation matrix (aka PSSM)

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
0201	-0.2	-1	-0.8	0.2	0.1	-0.9	-1.2	0.1	0.7	-0.1	0.4	0.1	0.4	0.5	-0.7	0.7	0.1	1.8	-0.1	-0.3
0202	0.5	0.5	-0.3	0.5	0.4	-0.8	-1	-0.5	0.2	-0.2	0	0.2	-0.4	0.3	-0.1	0.1	0.3	0.3	0.4	-0.9

Select residue pair below:

i_j

Score

Prob

Local Interactions:

i_j	Score	Prob
0201_0202	1.148	0.74
0202_0203	0.873	0.44
0200_0202	0.835	0.39
0202_0204	0.816	0.37

See all coupling residues
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