OPENSEQ.org -1516272175- GREMLIN Submission

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PRMT5 292-637

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Coupling matrix for [S:0187] and [N:0191]

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
A	0.7	0.3	-0.3	-0.5	-0.1	-0.3	0.3	0.1	0.7	0.6	-0.3	-0.3	-0.5	0.1	0.4	0.3	0.3	-0.2	-0.1	-0.2
F	-0.1	0	0	-0.1	0	0.5	0	0	-0.1	-0.1	-0.1	-0.1	-0.1	-0.2	-0.1	0.2	-0.1	-0.1	0	0
I	-0.1	0	0	-0.1	0	0	0	0	0.3	-0.1	-0.1	0.3	0.2	0.1	-0.1	-0.2	-0.1	-0.1	0	0
L	0	-0.1	0.3	-0.2	0	-0.1	-0.1	-0.1	0	-0.4	0.1	0.4	0.2	0.6	0.6	-0.5	-0.3	-0.2	0	-0.1
V	-0.3	-0.1	-0.1	-0.2	0	0.3	0	0.4	0.1	0.2	0.5	0	0.2	-0.6	0.4	-0.1	-0.3	-0.2	0	-0.1
M	-0.1	0	0	-0.1	0	0	0	0	-0.1	0.3	-0.1	-0.1	-0.1	0.2	-0.1	-0.2	-0.1	-0.1	0	0
W	0	0	0	0	0	0	0	0	-0.1	-0.1	0	-0.1	0	-0.1	-0.1	-0.1	-0.1	0	0	0
Y	-0.3	0.4	-0.1	1.8	0	0.3	0	-0.1	-0.3	-0.3	-0.2	-0.3	-0.2	-0.3	-0.3	-0.1	0.4	-0.2	0	-0.1
D	-0.5	-0.1	-0.2	0.8	-0.1	0.2	-0.1	0.3	0	0.3	0	0.1	-0.2	0.3	-0.2	0.2	-0.5	-0.3	-0.1	0
E	0.3	-0.1	0.2	0.9	-0.1	0.7	-0.1	0.1	-0.3	-0.5	0.3	0.3	0.1	-0.2	-0.4	-0.3	-0.6	0.3	0	-0.2
K	0	-0.1	-0.1	-0.2	0	-0.1	0	-0.1	0	0.3	0.1	-0.2	0	-0.1	-0.2	0.5	0	0.5	-0.1	-0.1
R	0.6	-0.1	-0.2	0	-0.1	-0.2	-0.1	0.2	0.9	0.1	-0.4	0.2	0	-0.6	-0.2	-0.5	-0.2	0.8	-0.1	0.3
H	-0.3	-0.1	0	-0.2	0	-0.1	0	-0.1	-0.4	-0.4	-0.2	0	0.6	0.3	-0.3	0.7	1.1	-0.2	-0.1	-0.1
N	-0.3	0	-0.1	0.3	0	-0.1	0	-0.1	-0.2	0.4	0.2	0.1	-0.2	-0.3	0.4	0.2	0.1	-0.2	0	-0.1
Q	-0.1	-0.1	0.6	-0.2	0.4	-0.2	-0.1	-0.1	0.9	0.1	-0.3	0.3	-0.3	0	-0.2	0.2	0.1	-0.3	-0.1	-0.1
S	-0.4	-0.2	-0.4	-0.6	-0.1	-0.4	-0.1	-0.3	-0.2	-0.5	0.6	-0.1	0.6	1.6	0.1	-0.1	0.3	-0.3	-0.2	0.8
T	-0.2	-0.1	0.2	-0.4	-0.1	-0.2	-0.1	-0.2	-0.1	-0.2	0.5	-0.2	0	0.5	0.2	0	0.6	-0.4	-0.1	-0.1
G	-0.3	-0.1	-0.1	-0.2	0	-0.1	0	-0.1	0.2	0.9	0	0.3	-0.2	-0.4	-0.4	-0.2	-0.3	1.3	0.3	-0.1
P	1.7	-0.3	0.1	-0.7	-0.3	-0.2	-0.2	-0.1	-0.5	0.1	-0.4	0.1	0.1	-0.5	1.1	0.4	0.1	0.2	0.1	-0.4
C	-0.1	0	0	0	0	0	0	0	-0.1	-0.1	0	-0.1	0	0	-0.1	-0.1	-0.1	0	0	0

Conservation matrix (aka PSSM)

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
0187	1	-1.1	-0.8	0	-0.1	-1	-1.4	-0.2	0.5	1.1	0.1	0.6	0.1	-0.2	0.5	1.1	0.5	0.1	1.4	-1.3
0191	0.7	-1.2	-0.6	0.1	-1.3	-0.5	-1.4	-0.7	0.8	0.8	0.3	0.8	0.1	1.6	0.8	1.2	0.6	0.2	-1.2	-0.9

Select residue pair below:

i_j	Score	Prob
0187_0191	1.209	0.79
0187_0193	0.934	0.51

Local Interactions:

i_j

Score

Prob

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