OPENSEQ.org -1516272175- GREMLIN Submission

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PRMT5 292-637

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Coupling matrix for [K:0137] and [I:0141]

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
A	0	-0.1	0.3	0.2	-0.4	-0.1	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.1
F	0	0	0.1	-0.2	0.1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.1
I	0	-0.1	-0.3	0.1	-0.3	0.2	0	0	0	0	0	0	0	0	0	0	0	0	0	0.3
L	-0.1	-0.2	0.3	0.5	0.4	0	0	0	0	0	0	0	0	0	0	-0.1	0	0	0	-0.2
V	0	-0.1	0.2	0.2	-0.1	-0.1	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.1
M	0	0	-0.2	0.1	-0.3	0.3	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.1
W	0	0	-0.2	-0.2	-0.2	-0.1	0	0	0	0	0	0	0	0	0	0.5	0	0	0	0
Y	0	0	0.2	0.1	-0.2	-0.1	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.1
D	0	0	-0.4	0.1	0.3	-0.1	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.1
E	0	0	0.4	-0.3	-0.4	-0.1	0	0	0	0	0	0	0	0	0	0	0	0	0	0.3
K	-0.2	0.5	0.4	0.6	-0.2	0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.2	-0.1	-0.1	-0.1	1
R	0.6	0	-0.5	0.5	0.9	0.7	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.6
H	0	0	0.8	-0.3	-0.3	-0.1	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.1
N	0	0	-0.1	-0.2	0.5	0.1	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.1
Q	-0.1	0.1	0.6	0.1	-0.1	-0.2	0	0	0	0	0	0	0	0	0	-0.1	0	0	0	-0.1
S	-0.1	0.1	0.5	-0.3	0	0.3	0	0	0	0	0	0	0	0	0	0	0	0	0	0.1
T	0.4	-0.1	-0.6	0.5	0.3	-0.2	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.2
G	0	-0.1	-0.1	-0.2	0.7	-0.1	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.1
P	-0.2	-0.2	0	0.6	0.2	-0.1	0	0	0	0	0	0	0	0	0	-0.1	0	0	0	0.8
C	0	0	0.2	-0.3	0.1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.1

Conservation matrix (aka PSSM)

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
0137	-0.3	-0.5	-0.3	0.4	-0.2	-0.4	-0.7	-0.4	-0.4	-0.3	1.1	1	-0.3	0	0.1	0.8	0	-0.1	1	-0.4
0141	0.1	0.2	2.5	2.3	2.1	0.6	-0.7	-0.7	-0.7	-0.7	-0.7	-0.7	-0.7	-0.7	-0.7	-0.4	-0.7	-0.7	-0.7	0.9

Select residue pair below:

i_j	Score	Prob
0137_0168	1.096	0.69
0137_0162	0.895	0.46
0137_0141	0.754	0.31

Local Interactions:

i_j	Score	Prob
0137_0139	0.817	0.37

See all coupling residues
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