OPENSEQ.org -1516272175- GREMLIN Submission

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PRMT5 292-637

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Coupling matrix for [E:0131] and [V:0133]

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
A	0.2	-0.1	-0.2	0.2	-0.3	-0.1	0.4	-0.1	0.4	-0.1	1	-0.4	-0.2	-0.1	0.6	-0.2	-0.2	-0.1	-0.2	-0.1
F	-0.2	-0.1	-0.1	-0.1	-0.1	0	0	0	-0.4	0.4	0	0.1	-0.1	0.1	-0.3	1	-0.2	-0.1	-0.1	0
I	0.2	0	-0.1	-0.1	-0.1	0	0	0	-0.1	0.4	-0.3	0.3	0.4	-0.2	-0.2	-0.2	-0.2	0	-0.1	0
L	-0.3	-0.1	-0.1	-0.1	-0.2	0	-0.1	0	-0.1	0.4	0.1	-0.2	-0.1	0.7	0.1	0	0.1	-0.1	-0.1	0
V	-0.3	-0.1	-0.1	-0.1	-0.1	0	-0.1	0	1.3	0.4	-0.1	-0.2	-0.1	0.4	-0.3	-0.3	-0.2	-0.1	-0.1	0
M	-0.1	0	0	0	0	0	0	0	-0.1	-0.1	0.3	-0.1	0	-0.1	-0.1	-0.1	-0.1	0	0	0
W	-0.1	0	0	0	0	0	0	0	-0.1	-0.2	-0.1	0.4	0	-0.1	-0.1	-0.1	-0.1	0	0	0
Y	-0.4	1.1	-0.1	-0.1	-0.2	-0.1	-0.1	-0.1	-0.2	-0.2	-0.2	0.2	-0.2	0.5	0.1	-0.1	0.4	-0.1	-0.1	0
D	-0.2	-0.5	0.5	0.2	0.9	0	-0.4	0.2	-0.1	0.2	0.1	-0.4	-0.3	0.1	0.6	0.2	0.3	-0.5	-0.1	0.1
E	0	-0.4	0	0.3	0.5	0	-0.3	-0.2	0.2	0.8	-1	-0.1	0.4	-0.1	0	0.1	0.8	0.4	-0.3	0.1
K	0.2	-0.1	0.3	-0.2	0.1	-0.1	-0.1	0	-0.1	-0.1	0.8	-0.3	-0.1	-0.2	0.1	0.1	-0.1	0.3	-0.2	-0.1
R	0.6	1	-0.1	0.3	-0.3	-0.1	-0.1	-0.1	-0.1	-0.8	-0.7	0	0.2	0.1	0.1	-0.6	0.1	0.3	0.5	-0.1
H	0.6	-0.1	-0.1	-0.2	0.5	-0.1	-0.1	-0.1	-0.2	0	0	-0.3	-0.2	-0.1	0.2	0.4	0.1	-0.1	-0.2	-0.1
N	-0.5	-0.2	-0.2	-0.2	-0.3	0.4	-0.1	-0.1	-0.3	-0.3	0.2	0.4	0.6	-0.5	0.1	0.3	0.5	0.3	0.3	-0.1
Q	0.2	-0.2	0.6	0.2	0.2	-0.1	-0.1	-0.1	0.1	-0.5	0.5	0.5	0	0.2	-0.6	-0.2	-0.1	-0.1	-0.2	-0.1
S	0.2	-0.2	-0.2	-0.2	-0.3	-0.1	0.3	-0.1	0.2	0.4	0.6	0	0	0	0.1	0	-0.5	-0.2	0.5	-0.1
T	0.1	-0.2	-0.2	0.1	0	-0.1	-0.1	0	-0.4	-0.3	0.4	0.7	-0.2	-0.4	0.4	0.2	-0.1	-0.2	0.8	-0.1
G	0.3	0	0	0	-0.1	0	0	0	-0.2	0.3	-0.2	-0.1	0	-0.1	-0.1	-0.1	-0.1	0.1	-0.1	0
P	-0.1	0	0	0	0	0	0	0	-0.1	0.3	-0.2	-0.1	0	-0.1	-0.1	-0.1	-0.1	0	0	0
C	-0.1	0	0	-0.1	-0.1	0	0	0	1	-0.3	-0.3	-0.1	-0.1	-0.1	-0.2	0.2	-0.1	0	-0.1	0

Conservation matrix (aka PSSM)

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
0131	0.3	-0.5	-0.6	-0.2	-0.2	-1.2	-1.2	0	1.9	1.9	0.3	0.4	0.2	0.6	0.5	0.6	0.8	-0.9	-1.1	-0.8
0133	0.7	-0.7	-0.4	-0.2	0.1	-0.9	-0.9	-1.2	1.1	0.8	1.4	0.5	-0.3	0.8	0.5	0.9	0.5	-0.6	0	-1.2

Select residue pair below:

i_j	Score	Prob
0133_0164	0.947	0.53

Local Interactions:

i_j	Score	Prob
0131_0133	0.821	0.38

See all coupling residues
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