OPENSEQ.org -1515484907- GREMLIN Submission

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PRMT5 1-300

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Coupling matrix for [E:0182] and [E:0183]

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
A	-0.1	-0.6	-0.4	0.2	-0.2	-0.2	0.1	-0.1	0.4	-0.1	0.3	-0.1	0.1	0.3	0.2	0.5	0	0.3	-0.1	-0.2
F	0	0.3	0.1	-0.2	0.3	-0.1	0	-0.2	0.3	-0.3	-0.1	-0.1	0.4	-0.3	0.4	-0.1	-0.1	-0.1	0	-0.1
I	0.1	0.7	0.1	-0.5	0	-0.1	-0.1	1.2	0.1	0	-0.1	-0.2	0.4	-0.2	-0.2	-0.3	-0.2	-0.1	0	-0.1
L	-0.1	1.4	0.1	-0.5	0.2	-0.3	-0.2	0.7	-0.2	-0.2	-0.2	-0.3	-0.3	0.8	-0.3	0.7	-0.1	-0.2	-0.1	-0.2
V	-0.1	-0.2	0	-0.1	-0.3	-0.1	-0.1	-0.1	0.2	1.3	-0.1	0.2	0.2	0.4	-0.2	-0.4	-0.2	-0.1	0	-0.1
M	0	0.4	0.3	-0.2	0.3	-0.1	0	-0.1	-0.3	-0.2	-0.1	-0.1	-0.1	0.4	-0.1	-0.1	-0.1	-0.1	0	-0.1
W	0	-0.2	-0.1	-0.1	-0.1	0.1	0	-0.1	0.5	-0.3	0	0	0	0.6	-0.1	-0.1	-0.1	0	0	0
Y	0	0.5	-0.1	0.1	-0.1	0.5	0	-0.1	-0.2	0.1	0	-0.1	-0.1	-0.2	0	-0.1	-0.1	-0.1	0	0
D	-0.1	-0.6	0.3	-0.7	-0.4	-0.2	-0.1	0	0.6	0.7	0.3	-0.3	-0.2	0.7	0.3	0.1	-0.3	0.3	-0.1	0.3
E	-0.2	0.1	0.1	0.3	-0.6	0.1	0.3	-0.1	0	0.5	0.2	0.1	0.4	-0.1	-0.3	-0.1	0.3	0.1	-0.1	-0.2
K	0.4	-0.2	-0.2	-0.2	-0.2	-0.1	0	-0.1	0	0.1	-0.1	0.8	0.3	-0.2	-0.1	-0.1	-0.1	-0.1	0	-0.1
R	0	-0.2	-0.2	0.3	-0.1	0	0	-0.2	0.2	0.2	0	-0.1	-0.1	-0.2	-0.1	-0.1	-0.1	0	0	0.5
H	0	-0.1	-0.1	-0.1	0.4	0	0	-0.1	-0.2	-0.1	0	0.4	-0.1	-0.1	0	-0.1	0.1	0	0	0
N	0	-0.3	-0.2	-0.2	0.2	0.9	0	-0.2	0.2	-0.3	-0.1	-0.1	-0.1	0.1	-0.1	-0.1	0.3	0.2	0	-0.1
Q	0	0.4	0.7	0.5	0.5	-0.1	-0.1	-0.2	-0.3	0	-0.1	-0.2	-0.2	-0.4	-0.2	-0.1	0.1	-0.1	0	-0.1
S	-0.1	-0.2	-0.1	0.5	0.3	-0.1	0.2	-0.3	-0.3	0.2	-0.2	-0.2	-0.3	-0.2	0.9	0.7	-0.3	0	0	-0.1
T	0	0	-0.2	0.1	0.1	-0.1	0	0.4	0	-0.3	-0.1	0.6	-0.1	-0.3	-0.1	-0.1	-0.1	-0.1	0	0.4
G	0	-0.2	-0.1	0.3	-0.1	0	0	-0.1	-0.2	-0.2	0	-0.1	-0.1	0.7	0	-0.1	0.4	-0.1	0	0
P	-0.1	0	0.4	1.6	0.1	-0.1	0.1	0	-0.2	-0.5	0.4	-0.2	-0.2	-0.7	-0.1	0.4	0.1	-0.2	-0.1	-0.1
C	0	-0.2	-0.1	-0.1	0	0	0	-0.1	-0.1	0.6	0	0	0	-0.1	0	-0.1	0	0	0	0

Conservation matrix (aka PSSM)

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
0182	0.5	-0.1	0.3	0.5	0	-0.3	-0.3	-0.4	0.8	1.3	-0.1	-0.4	-0.5	-0.2	-0.1	0.3	-0.4	-0.3	0.2	-0.7
0183	-0.8	1	0.3	1	0.1	-0.3	-0.7	0.4	0.8	1.2	-0.7	-0.2	-0.3	0.8	-0.5	0.3	-0.1	-0.6	-1.1	-0.5

Select residue pair below:

i_j	Score	Prob
0179_0182	0.905	0.35
0178_0182	0.823	0.27
0177_0182	0.818	0.27
0182_0202	0.790	0.25

Local Interactions:

i_j	Score	Prob
0182_0183	0.979	0.42
0182_0184	0.869	0.31

See all coupling residues
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