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PRMT5 1-300 Return to Main Page

Instructions
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Coupling matrix for [D:0019] and [L:0020]
- A F I L V M W Y D E K R H N Q S T G P C
A -0.1 -0.1 -0.1 0.5 -0.1 -0.1 0 -0.1 0 0 0 0 0 0 -0.1 0 0.4 0 0 0
F 0 0 0 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
I 0 0.4 -0.1 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 -0.1 0 0 0
L 0 0 -0.1 -0.1 0 0 0 0 0 0 0 0 0.5 0 -0.1 0 -0.1 0 0 0
V 0 -0.1 -0.1 -0.1 -0.1 0.4 0 0 0 0 0 0 0 0 0 0 -0.1 0 0 0
M 0 0 0 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
W 0 -0.1 -0.1 0.3 -0.1 0 0 0 0 0 0 0 0 0 0 0 -0.1 0 0 0
Y -0.1 -0.1 -0.2 0.8 -0.1 -0.1 0 -0.1 0 0 0 0 0 0 -0.1 0 0.2 0 0 -0.1
D -0.2 1.1 0.2 0.7 0.2 0.1 -0.1 0.4 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.4 -0.1 -0.3 0.3 -0.1 -0.4
E 0 -0.3 0.2 0.2 0.7 -0.3 -0.1 0.6 -0.1 -0.2 -0.1 -0.1 -0.2 -0.1 -0.4 0.1 1 -0.2 -0.1 0.5
K 0 -0.1 0.5 -0.3 -0.2 -0.1 0 -0.1 0 0 0 0 0 0 0.3 0 0.2 0 0.4 0
R 0 -0.1 0.8 0.2 -0.1 -0.1 0 -0.1 0 0 0 0 0 0 -0.1 0 -0.2 0 0 -0.1
H -0.1 -0.2 -0.2 -0.2 -0.1 -0.1 0 -0.1 0 0.4 0 0 -0.1 0 1.3 0 -0.3 0 0 -0.1
N -0.1 0.5 -0.1 -0.3 -0.1 0.4 0 -0.1 0 -0.1 0 0 0 0 -0.1 0 -0.1 0 0 0.5
Q 0.4 -0.1 0.5 -0.3 0.2 -0.1 0 -0.1 0 0 0 0 0 0 -0.1 0 -0.2 0 0 -0.1
S 0 -0.1 -0.2 0.5 -0.1 0 0 -0.1 0 0 0 0 0 0 -0.1 0 0.6 0 0 0
T 0 -0.1 -0.2 -0.2 -0.1 0 0 0.5 0 0 0 0 0 0 -0.1 0 0.3 0 0 0
G 0 0.3 -0.2 -0.1 0.4 0 0 -0.1 0 0 0 0 0 0 -0.1 0 -0.1 0 0 0
P 0 0 0 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
C 0 0 0 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0019 -0.1 -0.5 -0.2 -0.3 -0.3 -0.5 -0.3 0.1 0.5 1.2 0.2 0.1 0.3 0.2 0.1 0.1 -0.1 -0.1 -0.5 -0.5
0020 -0.2 1.1 1 1.3 0.6 -0.1 -0.7 0.4 -0.7 -0.3 -0.5 -0.7 -0.4 -0.7 0.2 -0.4 0.8 -0.4 -0.4 -0.2
Select residue pair below:
i_j Score Prob
0020_0041 0.875 0.32
0020_0105 0.806 0.26
Local Interactions:
i_j Score Prob
0019_0020 1.086 0.53
0020_0021 0.930 0.37
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M A A M A ...

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