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Instructions
  • Use the menu to the right to browse the coupling matrix, or select a position from the PSSM below to see what it is coupled with.
Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0001 1 -0.8 1.1 0.4 1.5 -0.8 -1.5 -0.7 -1.4 -1.4 -0.4 -0.3 -0.6 0 -1.5 2.1 2.9 -0.3 -1.5 -1.5
0002 0.8 -0.9 -0.3 -0.2 -0.3 -0.7 -1.7 -0.8 0.1 0.7 1.9 2.4 -0.1 0.9 0.9 0.8 0.4 0.3 -1.7 -1.7
0003 0.3 -1.1 -0.5 -0.5 -0.7 -0.6 -1.1 -0.1 -0.5 -0.4 0.1 1.7 -0.4 0.5 0.4 1.3 0 -0.5 3.4 -1.1
0004 0.7 0.6 2.6 3.4 1.5 1 -0.1 -0.8 -0.8 -0.8 -0.8 -0.5 -0.8 -0.8 -0.4 -0.8 0 -0.8 -0.8 -0.8
0005 0.4 -1.1 0.1 1.1 0.6 -0.8 -1.9 -1 0.1 1.3 2 1.9 -0.2 1 0.9 0.6 0.4 -0.2 -1.8 -1.6
0006 1.2 -1.4 -0.6 0.3 0 -0.7 -1.6 -0.8 0.6 1.7 1.8 1.3 -0.2 0.7 1.4 0.8 0.6 -0.3 -1.7 -1.8
0007 1.8 0.6 2.2 3 1.8 2 -0.9 -0.4 -0.9 -0.9 -0.9 -0.8 -0.9 -0.9 -0.9 -0.6 0.2 -0.8 -0.9 -0.8
0008 0.9 -1.3 0.6 0.3 0.7 0.4 -1.3 -0.6 -0.4 0.1 0.4 0.7 -0.6 0.5 0.3 1 1.2 -0.3 -1.3 -0.6
0009 0.6 -0.8 -0.6 -0.2 -0.3 -0.6 -1.4 -0.7 0.6 1.4 1.6 1.1 0.1 0.6 0.8 0.8 0.1 0.1 -1.1 -1.6
0010 0.8 -0.1 0.7 0.6 1.2 -0.3 -0.7 -0.7 -0.6 -0.4 -0.1 0.1 -0.4 -0.3 0.2 0.6 0.8 1.1 -1.4 -0.9
0011 1.2 -0.3 1.2 1.4 1 1.5 -0.5 -0.4 -0.8 -0.7 -0.8 -0.8 -0.7 -0.6 -0.7 0.3 0.7 -0.5 -0.8 -0.2
0012 0.3 -1 -0.5 0.2 -0.3 -0.4 -1.4 -1.2 0.9 1.2 1.6 1.4 0.1 0.6 1.2 0.6 0.1 0.5 -1.6 -1.3
0013 1.5 -1.3 -0.2 -0.2 -0.3 -0.6 -1.4 -1.1 0.9 1.3 1.4 1.8 0 0.5 1.4 0.8 -0.1 -0.1 -1.6 -1.3
0014 0.3 0.7 2.2 2.1 1.4 1.6 -0.1 0.1 -1 -0.7 -0.7 -0.3 -1 -1 -0.8 -0.8 0.3 -1 -1 -0.6
0015 3.6 -1.5 0.3 -0.1 -0.3 -0.7 -1.5 -1.3 -1.3 0.5 0.5 1 -1.2 -0.5 0.5 2.5 1.4 1.7 -1.5 -1.2
0016 1.1 -1.5 -1.1 -0.3 -1 -0.6 -1.6 -1.1 0.4 1.5 1.8 1.3 0.5 1.2 1.4 1.1 0.3 -0.1 -1.4 -1.3
0017 -0.2 0.1 -1.1 1.1 -1.1 0 -1.1 -0.8 -0.1 0.1 0.8 0.5 0.3 0.2 0.1 -0.3 -1 4.3 -0.9 -0.9
0018 -0.1 -1.2 -0.4 -0.8 -0.3 -1.2 -1 -0.8 1.8 1.8 0.8 0.7 0.7 1.7 0.8 -0.1 0.1 -0.2 -0.5 -1.2
0019 -0.3 1.2 -0.1 1.4 -0.7 -0.5 0 1.4 -0.1 0 0.3 0.2 -0.1 -1.1 -0.7 -0.2 0 -0.1 0.3 -1.1
0020 0.3 -1 -0.9 -0.8 -0.4 -1.4 -1.6 -1 2.2 1.1 0.4 0.1 0.1 1.1 0.7 1.2 0.9 0.5 0.2 -1.7
0021 0.6 -0.8 0.2 -0.1 0.8 -0.6 -1.7 -0.7 -0.1 1.2 0.5 0.7 0.2 -0.3 1.1 0.4 1 -0.1 -0.1 -1.4
0022 0.4 -0.9 0.1 -0.3 0.3 -0.7 -1.3 -0.6 0.5 0.6 1.1 0.3 0.2 0 0.5 0.5 0.1 -0.3 0.7 -1
0023 -0.3 0 1.5 1.7 0.7 0.1 -0.9 -0.8 -0.3 -0.1 -0.1 -0.6 -0.4 -0.3 0.2 0.3 0.5 -0.6 0.4 -0.6
0024 0.5 -0.9 0 -0.3 -0.2 -0.9 -1.3 -0.4 1 0.9 0.6 0.5 0.1 0.1 0.1 0.8 0.4 -0.1 1 -1.1
0025 0.3 0.1 1 0.9 1 -0.1 -1.4 0 0 -0.1 -0.3 -0.2 -0.3 0 -0.3 0.6 0.5 -0.7 0.1 -0.9
0026 0.2 -0.7 -0.5 -0.5 -0.4 -0.9 -1.9 -0.1 0.6 0.8 1.4 1.1 0.4 1 0.7 1 0.3 0.3 0.1 -1.8
0027 1 -0.8 -0.7 -0.2 -0.5 -0.7 -1.2 -0.1 0.4 0.3 0.2 0.4 0 0.2 -0.3 0.6 0 2.1 0.9 -1.1
0028 -0.1 -0.7 0.4 -0.7 -0.3 -0.7 -1.6 -0.3 0.9 -0.1 0.3 -0.2 0.1 0.7 -0.3 1.2 0.6 1 0.1 -1
0029 0.1 -0.9 -0.3 -0.7 -0.7 -1 -1.1 -0.1 1.8 0.6 0.5 0.6 -0.1 0.9 0.1 0.6 0.1 0.6 0.2 -1.1
0030 -0.6 -0.7 -0.7 -0.7 0 -0.5 -0.7 -0.7 1.6 5 -0.7 -0.2 -0.4 -0.3 0.1 -0.3 -0.2 -0.3 1.2 -0.7
- A F I L V M W Y D E K R H N Q S T G P C
0031 0.4 1.7 0.9 2.3 0.6 0.8 -0.2 0.6 -0.8 -0.6 -0.8 -0.4 -0.2 -0.6 -0.8 -0.1 0.4 -0.8 -0.8 -0.8
0032 0.6 -0.5 -0.1 -0.4 0.3 -0.6 -0.9 0.3 1.1 0 0.5 0.3 -0.3 0.5 0.6 0.2 0.1 0.7 -0.9 -0.7
0033 0.2 -1.2 0.1 0.7 0.4 0.1 -1.3 -1 1.3 1.9 0.6 1.1 -0.6 -0.1 1.8 0.5 0.2 -0.5 -0.6 -1.7
0034 0.4 0.4 1.7 3.5 1.6 1.7 -0.7 -0.5 -0.7 -0.7 -0.7 -0.7 -0.7 -0.7 -0.7 -0.5 0.3 -0.7 -0.7 -0.7
0035 3.2 -1.1 0.6 0 1 -0.6 -1.4 0.1 -1.4 -0.3 -0.5 -1.1 -1 -0.3 -0.6 2.5 2.1 2.8 -1.4 -0.8
0036 0.5 -1.1 -0.4 0 0 -0.9 -1.6 -0.7 1.1 1.4 1.1 1.8 0.7 1.1 1 0.4 0.3 0 -1.7 -1.3
0037 1.7 -1.1 -0.2 -0.2 0.1 -1.1 -1.1 -0.5 0.8 0.5 -0.1 -0.5 -0.1 1.6 0.7 2 0.3 0.5 -1.1 -0.9
0038 0.1 0.5 1.6 1.4 1.5 0.9 -0.6 0.5 -0.6 -0.6 -0.6 -0.6 -0.4 -0.6 -0.6 -0.4 -0.2 -0.6 -0.6 0.1
0039 0.3 -1 -0.2 0 -0.5 -0.6 -1 -0.8 1 0 0.9 0.5 0 2.6 0.7 0.7 0 0.3 -1 -1
0040 0.5 -0.1 -0.7 0.1 -0.3 -1 -1.6 0.1 1.2 1.4 0.8 0.8 0.6 0.6 1.2 0.8 0.5 -0.4 -1.6 -1.5
0041 0.9 0.2 0.6 2 0.6 2.8 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 -0.1 0.7 -0.6 -0.6 -0.6
0042 -0.4 -0.5 0.6 0 0.8 0.3 -0.7 -0.6 -0.1 0 0.3 0.2 0 0 1.2 0.7 -0.5 0.5 -0.7 -0.4
0043 1 -0.9 -0.5 -0.4 0 -0.9 -1.9 -0.7 1.1 1.5 0.9 1.3 0 0.6 0.9 0.8 0.4 0.6 -1.3 -1.5
0044 0.8 -1.4 -1.1 -1 -0.5 -0.8 -1.6 -0.7 1 1.4 1.2 1.4 -0.1 1.4 1.8 1.7 0.8 -0.6 -1.6 -1.4
0045 -0.4 0.3 2.2 2.3 1.6 1.3 -0.7 -0.7 -0.9 -0.2 -0.9 -0.9 -0.9 0.1 0.4 -0.6 0.4 -0.9 -0.9 -0.9
0046 0.7 -1 -0.5 -0.6 -0.2 -0.9 -1.5 -0.7 0.3 0.9 1.9 1.8 0.2 1.2 1.5 0.7 -0.2 0.1 -1.5 -1.2
0047 0.7 -1.2 -0.4 0.1 -0.6 -0.8 -1.7 -1 1.4 1.9 1.1 1.2 0.3 1 1.1 0.8 0.7 -0.2 -1.7 -1.4
0048 1.3 -0.9 0.6 1.2 0.4 0.8 -1.7 0.3 -0.8 -0.1 0.4 0 0.4 0.8 0.5 1.6 1.3 -0.8 -1.7 -1.6
0049 -0.5 -0.4 1.8 1 1.4 0.8 -1 -0.3 -0.3 -0.1 -0.4 -0.2 0 0 0.6 0.2 0.6 -0.7 -1.1 -1.1
0050 1.2 -1.2 -0.5 0.1 -0.6 -1.3 -1.8 -0.7 0.9 1.5 1.1 1.2 -0.1 0.8 0.8 1.1 0.7 0.4 -1.9 -1.5
0051 0.9 -1.2 -0.3 0.3 -0.1 -0.5 -1.1 -0.9 0.5 1.5 1.2 0.8 -0.2 0.2 1 0.7 0.9 0 -1.5 -1.5
0052 0.5 -0.4 2.2 2.5 1.9 0.7 -1 -0.2 -1.3 -0.7 -0.7 -0.1 -0.7 0.1 -0.1 0.1 0.5 -0.5 -1.3 -1.3
0053 0.3 -1.1 -0.1 0.9 -0.3 0.1 -1.3 -0.9 0.3 1.3 1.4 1 -0.5 0.2 1.5 -0.2 0.7 -0.1 -1.3 -1.3
0054 0.6 -0.8 -0.2 0.1 0 0.3 -1.5 -0.9 0.7 1.3 0.6 0.8 -0.5 0.6 1.1 0.8 0.4 -0.1 -1.5 -1.3
0055 1.3 -1.2 -0.4 0.1 -0.3 -0.8 -1.3 -1.3 0.2 1.3 0.7 0.8 -0.3 0.4 1.4 1.6 0.2 -0.4 -1.3 -1.3
0056 0.1 -0.3 -0.3 -0.2 -0.5 -0.3 -0.7 -0.7 0.2 1.2 0.9 0.5 -0.2 0.3 0.7 0.9 0.4 -0.1 -0.7 -0.2
0057 0.6 -1.1 -0.3 0.1 -0.5 -0.7 -1.1 -0.9 0.7 1.2 0.9 0.6 -0.2 1.2 1.1 0.7 0.4 0.2 -1.3 -1.3
0058 -0.5 -0.5 -0.5 0.2 -0.5 -0.3 -0.7 0.5 -0.2 1.7 1.4 0.8 0 0 1.7 -0.2 0.5 -0.6 -1.2 -1.2
0059 0.1 0.9 0.4 2.6 0.8 0.9 -0.8 0.4 -0.8 -0.8 -0.6 0.1 -0.8 0.2 -0.1 0 0.1 -0.6 -0.8 -0.8
0060 0.5 -0.8 -0.9 -0.2 -0.5 -0.2 -0.9 -0.6 0.6 1.6 1 0.3 -0.3 0.1 1.2 0.5 -0.2 -0.1 -1.1 -1.1
- A F I L V M W Y D E K R H N Q S T G P C
0061 1.7 -0.8 -0.1 -0.2 -0.5 -0.5 -0.8 -0.7 0.5 0.3 -0.2 0.8 -0.5 0.7 -0.1 1.5 1.1 0.3 -0.8 -0.6
0062 -0.1 0.3 2.3 2.5 1.9 0.2 -0.7 -0.7 -0.7 -0.7 -0.7 -0.7 -0.7 -0.7 -0.7 -0.7 0.5 -0.7 -0.7 -0.7
0063 -0.6 1.1 1.7 2.4 0.6 0.7 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 -0.2 -0.6 -0.6 -0.6 -0.3 -0.6 -0.6 -0.6
0064 0.9 -0.8 -0.7 -0.2 -0.9 -0.8 -1.1 -0.6 0.8 1.1 0.1 0.3 -0.9 0.9 0 1.1 0.3 0.1 -1.1 -1.1
Select residue pair below:
i_j Score Prob
0013_0018 3.999 1.00
0027_0032 2.872 1.00
0029_0032 2.336 1.00
0023_0035 2.064 1.00
0022_0046 2.049 1.00
0014_0041 1.951 1.00
0023_0039 1.885 1.00
0014_0042 1.878 1.00
0008_0037 1.854 1.00
0011_0037 1.787 1.00
0007_0038 1.761 1.00
0020_0046 1.574 1.00
0008_0033 1.553 1.00
0013_0021 1.440 1.00
0022_0042 1.414 1.00
0038_0041 1.277 0.99
0022_0043 1.276 0.99
0019_0045 1.257 0.99
0005_0008 1.239 0.98
0010_0038 1.211 0.98
0022_0039 1.187 0.98
0059_0062 1.177 0.98
0012_0033 1.167 0.97
0011_0034 1.142 0.97
0018_0021 1.085 0.96
0041_0045 1.076 0.95
0006_0024 1.075 0.95
0055_0058 1.047 0.94
0012_0037 1.032 0.94
0033_0036 1.004 0.93
0044_0048 1.004 0.93
0057_0060 0.990 0.92
0007_0023 0.978 0.91
0044_0047 0.957 0.90
0010_0023 0.952 0.90
0051_0055 0.927 0.88
0004_0034 0.924 0.88
0028_0032 0.902 0.86
0061_0064 0.884 0.84
0017_0053 0.881 0.84
0043_0047 0.875 0.84
0025_0036 0.867 0.83
0002_0026 0.864 0.83
0005_0009 0.861 0.82
0056_0060 0.843 0.80
0011_0038 0.840 0.80
0003_0037 0.829 0.79
0002_0025 0.821 0.78
0039_0042 0.820 0.78
0056_0063 0.811 0.77
0019_0042 0.810 0.77
0013_0016 0.810 0.77
0044_0049 0.808 0.76
0006_0009 0.793 0.74
0040_0044 0.785 0.73
0019_0049 0.781 0.73
0004_0058 0.773 0.72
0056_0059 0.765 0.71
0052_0056 0.736 0.66
0059_0063 0.725 0.65
0046_0050 0.717 0.63
0040_0043 0.714 0.63
0002_0009 0.712 0.63
0009_0012 0.698 0.60
0036_0040 0.687 0.58
0053_0057 0.684 0.58
0015_0040 0.684 0.58
0024_0039 0.668 0.55
0010_0021 0.664 0.55
0049_0053 0.658 0.54
0038_0042 0.655 0.53
0009_0024 0.654 0.53
0042_0045 0.636 0.50
0002_0040 0.633 0.49
0003_0038 0.625 0.48
0057_0064 0.618 0.47
0012_0036 0.617 0.47
0025_0039 0.615 0.46
0014_0038 0.611 0.46
0011_0049 0.610 0.45
0053_0056 0.607 0.45
0001_0008 0.588 0.42
0008_0012 0.586 0.41
0048_0051 0.583 0.41
0058_0061 0.580 0.40
0050_0054 0.580 0.40
0007_0031 0.576 0.40
0024_0036 0.570 0.39
0017_0056 0.568 0.38
0051_0054 0.564 0.38
0006_0047 0.557 0.37
0042_0046 0.556 0.36
0011_0031 0.555 0.36
0031_0049 0.546 0.35
0016_0047 0.545 0.35
Local Interactions:
i_j Score Prob
0018_0020 3.079 1.00
0055_0056 1.734 1.00
0028_0029 1.483 1.00
0025_0027 1.372 0.99
0027_0029 1.346 0.99
0048_0049 1.186 0.98
0059_0060 1.021 0.93
0030_0032 0.999 0.92
0061_0062 0.998 0.92
0024_0026 0.948 0.89
0062_0063 0.928 0.88
0015_0016 0.896 0.86
0010_0011 0.891 0.85
0024_0025 0.833 0.79
0022_0023 0.748 0.68
0059_0061 0.748 0.68
0052_0054 0.721 0.64
0063_0064 0.712 0.63
0054_0055 0.703 0.61
0029_0031 0.678 0.57
0026_0027 0.668 0.55
0018_0019 0.635 0.50
0051_0052 0.632 0.49
0027_0028 0.624 0.48
0031_0032 0.618 0.47
0057_0058 0.609 0.45
0056_0057 0.596 0.43
0008_0009 0.592 0.42
0060_0061 0.589 0.42
0041_0042 0.578 0.40
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: N N Q V K ...
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