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OPENSEQ.org
MAA - Maltose O-acetyltransferase
UniProt: P77791 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14239
Length: 183 (183)
Sequences: 1772
Seq/Len: 9.68
MAA
Paralog alert: 0.45 [within 20: 0.02] - ratio of genomes with paralogs
Cluster includes: CAIE MAA PAAY THGA WBBJ WCAF YRDA
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
88_M 94_I 4.938 1.00
108_I 130_V 4.446 1.00
153_N 169_N 3.433 1.00
166_V 172_V 3.169 1.00
157_A 173_G 2.772 1.00
79_N 99_N 2.769 1.00
133_G 152_D 2.697 1.00
56_Q 75_F 2.637 1.00
138_I 144_I 2.533 1.00
109_Y 140_G 2.478 1.00
85_D 105_G 2.409 1.00
145_N 158_S 2.363 1.00
134_N 152_D 2.303 1.00
152_D 168_D 2.302 1.00
154_V 168_D 2.186 1.00
4_E 7_K 2.182 1.00
108_I 132_I 2.145 1.00
75_F 95_R 2.117 1.00
98_D 134_N 2.106 1.00
135_N 153_N 2.073 1.00
78_N 98_D 2.063 1.00
24_D 72_Y 1.969 1.00
173_G 180_I 1.948 1.00
58_T 78_N 1.916 1.00
156_V 166_V 1.885 1.00
42_E 45_L 1.883 1.00
99_N 135_N 1.837 1.00
154_V 170_V 1.758 1.00
160_A 177_A 1.711 1.00
95_R 131_T 1.701 1.00
76_L 80_F 1.685 1.00
28_A 53_L 1.669 1.00
138_I 142_A 1.566 1.00
33_H 37_H 1.557 1.00
5_K 24_D 1.557 1.00
115_I 155_V 1.547 1.00
100_C 134_N 1.535 1.00
131_T 149_T 1.531 1.00
3_T 6_E 1.529 1.00
91_V 127_G 1.52 1.00
33_H 40_A 1.516 1.00
156_V 172_V 1.497 1.00
92_C 127_G 1.472 1.00
102_L 108_I 1.459 1.00
172_V 177_A 1.445 1.00
154_V 166_V 1.439 1.00
115_I 171_V 1.429 1.00
80_F 98_D 1.419 0.99
59_E 79_N 1.412 0.99
107_H 141_R 1.392 0.99
80_F 134_N 1.353 0.99
34_R 52_D 1.332 0.99
96_I 102_L 1.327 0.99
47_Q 51_A 1.324 0.99
57_V 60_A 1.302 0.99
77_G 98_D 1.292 0.99
108_I 144_I 1.279 0.99
170_V 182_K 1.271 0.99
75_F 93_P 1.268 0.99
45_L 48_Q 1.258 0.99
27_R 31_L 1.256 0.98
28_A 32_I 1.251 0.98
121_N 135_N 1.242 0.98
87_V 105_G 1.238 0.98
133_G 154_V 1.234 0.98
80_F 100_C 1.229 0.98
68_C 74_I 1.223 0.98
167_P 179_I 1.189 0.98
170_V 179_I 1.171 0.97
66_F 74_I 1.169 0.97
35_Y 50_L 1.166 0.97
82_A 102_L 1.165 0.97
97_G 134_N 1.156 0.97
5_K 72_Y 1.15 0.97
5_K 9_I 1.112 0.96
107_H 143_V 1.109 0.96
100_C 152_D 1.104 0.96
167_P 172_V 1.099 0.96
107_H 140_G 1.095 0.96
106_V 142_A 1.09 0.95
30_Q 41_E 1.086 0.95
172_V 179_I 1.085 0.95
31_L 52_D 1.075 0.95
171_V 183_L 1.049 0.94
34_R 39_L 1.029 0.93
133_G 149_T 1.021 0.93
76_L 96_I 1.013 0.93
100_C 136_V 1.002 0.92
148_V 164_K 1.001 0.92
82_A 88_M 1 0.92
82_A 86_C 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3srtA211000.186Contact Map0.828
2p2oA611000.193Contact Map0.875
3fttA10.99451000.198Contact Map0.762
1krrA311000.205Contact Map0.834
3hjjA311000.206Contact Map0.875
3nz2A120.98911000.223Contact Map0.932
1ocxA30.99451000.235Contact Map0.854
4ea9A10.85251000.532Contact Map0.751
3vbiA30.879899.90.534Contact Map0.875
3q1xA10.912699.90.538Contact Map0.439
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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