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TATA - Sec-independent protein translocase protein TatA
UniProt: P69428 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11478
Length: 89 (87)
Sequences: 119
Seq/Len: 1.37

TATA
Paralog alert: 0.06 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: TATA TATE
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
56_D 59_F 2.543 1.00
4_I 9_L 2.25 0.99
30_S 35_S 1.934 0.97
13_A 35_S 1.818 0.95
4_I 8_Q 1.744 0.94
8_Q 11_I 1.723 0.93
5_S 10_L 1.703 0.92
2_G 6_I 1.652 0.91
3_G 11_I 1.569 0.88
13_A 88_Q 1.546 0.87
13_A 26_G 1.538 0.86
4_I 11_I 1.523 0.85
16_V 36_I 1.397 0.78
27_S 35_S 1.394 0.78
17_V 64_I 1.393 0.78
3_G 51_D 1.367 0.76
16_V 69_A 1.36 0.75
3_G 9_L 1.291 0.70
27_S 41_K 1.276 0.68
37_K 86_K 1.261 0.67
28_I 35_S 1.257 0.67
36_I 84_H 1.194 0.61
35_S 82_K 1.181 0.60
12_I 15_I 1.168 0.58
12_I 59_F 1.163 0.58
61_A 67_K 1.137 0.55
36_I 89_V 1.118 0.53
60_T 67_K 1.114 0.53
19_L 38_G 1.111 0.53
4_I 19_L 1.096 0.51
24_K 42_A 1.091 0.51
47_E 85_D 1.082 0.50
23_K 27_S 1.08 0.50
43_M 54_S 1.069 0.49
9_L 42_A 1.069 0.49
41_K 59_F 1.047 0.46
43_M 81_A 1.031 0.45
2_G 7_W 1.02 0.44
12_I 19_L 1.01 0.43
41_K 58_D 1.008 0.42
8_Q 42_A 1.007 0.42
41_K 56_D 1 0.42
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2lzrA10.61899.30.619Contact Map0.08
2l16A10.820299.20.626Contact Map0.109
4fu6A10.943816.50.92Contact Map0.043
2daqA10.67427.10.932Contact Map0.031
3g6mA10.584370.933Contact Map0.045
1edqA10.34836.20.934Contact Map0
1ll7A20.62925.90.935Contact Map0.037
1ri0A10.64045.70.935Contact Map0.074
4ld6A10.741650.937Contact Map0.034
1w9pA20.62924.80.937Contact Map0.04

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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