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YJIA - Uncharacterized GTP-binding protein YjiA
UniProt: P24203 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10021
Length: 318 (312)
Sequences: 2651
Seq/Len: 8.50
YJIA
Paralog alert: 0.63 [within 20: 0.05] - ratio of genomes with paralogs
Cluster includes: YEIR YJIA
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
170_H 184_T 5.729 1.00
306_E 310_R 4.999 1.00
156_L 185_V 4.269 1.00
229_V 314_A 3.214 1.00
155_I 173_L 3.045 1.00
161_D 186_T 2.954 1.00
158_T 185_V 2.816 1.00
9_L 21_L 2.567 1.00
170_H 174_A 2.518 1.00
181_P 194_L 2.398 1.00
243_V 312_A 2.299 1.00
23_H 189_D 2.289 1.00
24_I 95_V 2.237 1.00
169_L 173_L 2.23 1.00
94_L 121_Y 2.216 1.00
132_A 157_L 2.181 1.00
310_R 314_A 2.105 1.00
129_L 158_T 2.104 1.00
305_P 308_E 2.083 1.00
177_N 180_A 2.017 1.00
236_D 239_E 1.993 1.00
240_V 264_I 1.933 1.00
7_T 124_D 1.93 1.00
166_A 170_H 1.905 1.00
31_Y 93_R 1.904 1.00
34_A 80_L 1.871 1.00
10_T 128_A 1.87 1.00
77_L 94_L 1.812 1.00
227_I 309_I 1.793 1.00
23_H 27_E 1.735 1.00
140_N 172_R 1.703 1.00
3_P 122_L 1.691 1.00
44_S 59_T 1.687 1.00
32_K 92_D 1.677 1.00
64_C 67_C 1.671 1.00
238_S 242_R 1.647 1.00
24_I 192_L 1.634 1.00
39_E 44_S 1.623 1.00
10_T 126_V 1.614 1.00
185_V 188_G 1.614 1.00
125_G 154_R 1.599 1.00
165_E 168_K 1.561 1.00
154_R 181_P 1.56 1.00
31_Y 193_G 1.555 1.00
160_T 184_T 1.548 1.00
167_E 170_H 1.533 1.00
174_A 182_V 1.512 1.00
230_E 296_T 1.512 1.00
160_T 166_A 1.507 1.00
44_S 47_D 1.493 1.00
25_L 35_V 1.492 1.00
20_L 188_G 1.486 1.00
135_A 149_V 1.479 1.00
14_G 17_K 1.465 0.99
132_A 166_A 1.463 0.99
39_E 47_D 1.445 0.99
99_T 102_A 1.439 0.99
167_E 171_E 1.434 0.99
98_C 102_A 1.42 0.99
158_T 187_H 1.416 0.99
43_V 228_V 1.409 0.99
186_T 189_D 1.404 0.99
149_V 155_I 1.4 0.99
237_I 241_S 1.398 0.99
23_H 188_G 1.385 0.99
308_E 312_A 1.383 0.99
181_P 200_G 1.379 0.99
4_I 94_L 1.372 0.99
152_A 177_N 1.37 0.99
234_P 263_W 1.369 0.99
262_L 295_S 1.366 0.99
229_V 235_V 1.364 0.99
15_A 129_L 1.336 0.99
156_L 183_Y 1.321 0.99
179_R 205_E 1.315 0.99
20_L 129_L 1.311 0.99
128_A 152_A 1.297 0.98
131_D 159_K 1.295 0.98
166_A 184_T 1.276 0.98
212_P 215_H 1.269 0.98
13_L 16_G 1.265 0.98
122_L 197_N 1.258 0.98
14_G 18_T 1.253 0.98
191_D 194_L 1.222 0.97
13_L 17_K 1.218 0.97
103_D 147_S 1.215 0.97
167_E 184_T 1.213 0.97
152_A 155_I 1.212 0.97
227_I 310_R 1.211 0.97
236_D 265_D 1.202 0.97
308_E 311_A 1.2 0.97
307_E 311_A 1.199 0.97
108_I 126_V 1.199 0.97
307_E 310_R 1.196 0.97
108_I 123_L 1.189 0.97
149_V 173_L 1.188 0.97
170_H 182_V 1.184 0.97
81_L 94_L 1.182 0.97
235_V 313_F 1.175 0.97
240_V 262_L 1.17 0.97
72_E 110_T 1.168 0.96
132_A 173_L 1.166 0.96
183_Y 190_I 1.16 0.96
235_V 317_R 1.152 0.96
288_W 292_K 1.15 0.96
36_I 76_A 1.147 0.96
11_G 14_G 1.147 0.96
65_I 96_I 1.143 0.96
13_L 38_N 1.142 0.96
8_L 111_F 1.134 0.96
241_S 245_E 1.129 0.95
16_G 19_T 1.127 0.95
37_E 45_V 1.123 0.95
243_V 316_L 1.121 0.95
229_V 313_F 1.117 0.95
301_G 304_L 1.108 0.95
127_I 307_E 1.097 0.94
227_I 306_E 1.097 0.94
290_D 293_P 1.095 0.94
297_M 305_P 1.091 0.94
289_G 292_K 1.086 0.94
77_L 121_Y 1.085 0.94
237_I 264_I 1.082 0.94
7_T 93_R 1.079 0.94
33_I 93_R 1.077 0.94
158_T 188_G 1.075 0.94
40_F 102_A 1.068 0.93
235_V 240_V 1.066 0.93
190_I 195_L 1.061 0.93
236_D 266_G 1.056 0.93
71_N 75_D 1.053 0.93
157_L 170_H 1.051 0.93
311_A 314_A 1.049 0.93
154_R 183_Y 1.049 0.93
86_K 91_F 1.037 0.92
6_V 96_I 1.035 0.92
81_L 121_Y 1.034 0.92
22_R 41_G 1.029 0.92
156_L 184_T 1.026 0.91
211_K 214_F 1.025 0.91
23_H 26_N 1.022 0.91
277_Q 281_S 1.017 0.91
13_L 18_T 1.017 0.91
84_L 91_F 1.014 0.91
39_E 102_A 1.007 0.90
65_I 73_L 1.006 0.90
129_L 188_G 1.006 0.90
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1nijA111000.292Contact Map0.566
2wsmA20.591299.90.74Contact Map0.654
2hf9A20.581899.80.747Contact Map0.673
1xjcA10.503199.80.759Contact Map0.351
4hi0E20.581899.80.763Contact Map0.661
1yrbA20.701399.70.78Contact Map0.446
2qm8A20.735899.50.809Contact Map0.497
2wwwA40.764299.40.818Contact Map0.586
3p32A10.795699.20.842Contact Map0.582
2p67A10.776799.10.844Contact Map0.575
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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