May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
HCAC - HCAD
UniProt: P0ABW0 - P77650
Length: 506
Sequences: 846
Seq/Len: 1.70
I_Prob: 0.00
HCAC - 3-phenylpropionate/cinnamic acid dioxygenase ferredoxin subunit
Paralog alert: 0.55 [within 20: 0.08] - ratio of genomes with paralogs
Cluster includes: HCAC NIRD 		HCAD - 3-phenylpropionate/cinnamic acid dioxygenase ferredoxin--NAD(+) reductase component
Paralog alert: 0.87 [within 20: 0.11] - ratio of genomes with paralogs
Cluster includes: DHNA DLDH GSHR HCAD NORW STHA TRXB YKGC
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
2gagA:B:B:AContact Map
1y56A:B:AContact Map


 Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
28_L 210_E 1.04 0.00
73_T 135_A 0.97 0.00
40_D 189_Q 0.92 0.00
6_A 231_D 0.90 0.00
60_V 73_V 0.88 0.00
7_C 212_V 0.86 0.00
88_Y 298_Q 0.84 0.00
11_D 242_N 0.82 0.00
85_L 172_V 0.81 0.00
2_N 228_L 0.79 0.00
88_Y 257_I 0.79 0.00
49_M 150_I 0.78 0.00
4_I 228_L 0.77 0.00
12_V 61_Q 0.76 0.00
41_R 189_Q 0.75 0.00
69_F 8_I 0.74 0.00
6_A 77_S 0.74 0.00
92_V 9_V 0.74 0.00
97_I 118_L 0.73 0.00
25_V 358_G 0.73 0.00
77_L 162_S 0.73 0.00
92_V 262_A 0.72 0.00
49_M 259_I 0.72 0.00
11_D 172_V 0.72 0.00
99_I 180_M 0.72 0.00
26_I 78_G 0.72 0.00
73_T 232_V 0.72 0.00
67_A 182_R 0.71 0.00
88_Y 205_L 0.71 0.00
35_F 352_W 0.71 0.00
88_Y 106_I 0.71 0.00
34_E 194_Q 0.70 0.00
87_T 266_C 0.70 0.00
80_P 169_K 0.70 0.00
26_I 91_L 0.69 0.00
92_V 73_V 0.69 0.00
93_E 271_F 0.68 0.00
22_T 66_N 0.68 0.00
28_L 30_E 0.68 0.00
20_I 248_E 0.68 0.00
92_V 257_I 0.68 0.00
34_E 70_E 0.68 0.00
34_E 253_T 0.68 0.00
90_V 192_L 0.68 0.00
24_P 7_I 0.67 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
Page generated in 0.4669 seconds.