| UniProt: | Q93K97 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12184 | ||
| Length: | 209 (191) | ||
| Sequences: | 2506 | ||
| Seq/Len: | 13.12 |
| ADPP
Paralog alert: 0.40 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: ADPP NUDE NUDK |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 61_V | 94_M | 3.178 | 1.00 | |
| 123_R | 147_E | 2.75 | 1.00 | |
| 106_E | 110_R | 2.735 | 1.00 | |
| 66_D | 71_E | 2.664 | 1.00 | |
| 122_K | 148_V | 2.565 | 1.00 | |
| 92_L | 169_H | 2.565 | 1.00 | |
| 26_R | 30_S | 2.465 | 1.00 | |
| 22_E | 33_L | 2.405 | 1.00 | |
| 125_K | 147_E | 2.4 | 1.00 | |
| 176_A | 194_L | 2.373 | 1.00 | |
| 76_E | 167_R | 2.327 | 1.00 | |
| 104_S | 107_D | 2.322 | 1.00 | |
| 105_V | 142_S | 2.287 | 1.00 | |
| 178_Q | 182_E | 2.276 | 1.00 | |
| 114_I | 120_I | 2.263 | 1.00 | |
| 71_E | 172_S | 2.238 | 1.00 | |
| 73_V | 170_V | 2.169 | 1.00 | |
| 71_E | 170_V | 2.096 | 1.00 | |
| 77_Q | 93_E | 2.095 | 1.00 | |
| 103_E | 111_R | 2.082 | 1.00 | |
| 110_R | 124_T | 1.986 | 1.00 | |
| 129_S | 140_R | 1.974 | 1.00 | |
| 126_P | 142_S | 1.94 | 1.00 | |
| 126_P | 129_S | 1.936 | 1.00 | |
| 17_E | 39_R | 1.91 | 1.00 | |
| 99_I | 108_V | 1.894 | 1.00 | |
| 62_L | 109_A | 1.888 | 1.00 | |
| 21_R | 32_D | 1.87 | 1.00 | |
| 175_Q | 178_Q | 1.822 | 1.00 | |
| 39_R | 45_M | 1.817 | 1.00 | |
| 123_R | 148_V | 1.793 | 1.00 | |
| 129_S | 142_S | 1.767 | 1.00 | |
| 63_L | 193_A | 1.758 | 1.00 | |
| 76_E | 169_H | 1.717 | 1.00 | |
| 23_T | 26_R | 1.712 | 1.00 | |
| 171_V | 179_W | 1.706 | 1.00 | |
| 106_E | 124_T | 1.684 | 1.00 | |
| 172_S | 175_Q | 1.681 | 1.00 | |
| 27_G | 52_E | 1.658 | 1.00 | |
| 73_V | 119_L | 1.65 | 1.00 | |
| 55_E | 138_S | 1.647 | 1.00 | |
| 127_V | 145_V | 1.574 | 1.00 | |
| 179_W | 184_K | 1.572 | 1.00 | |
| 66_D | 170_V | 1.56 | 1.00 | |
| 107_D | 110_R | 1.539 | 1.00 | |
| 131_L | 186_D | 1.51 | 1.00 | |
| 94_M | 193_A | 1.481 | 1.00 | |
| 18_I | 80_I | 1.472 | 1.00 | |
| 108_V | 111_R | 1.46 | 1.00 | |
| 177_Y | 198_Q | 1.452 | 1.00 | |
| 113_A | 121_V | 1.442 | 1.00 | |
| 195_Q | 199_L | 1.37 | 0.99 | |
| 180_V | 191_V | 1.322 | 0.99 | |
| 122_K | 150_A | 1.311 | 0.99 | |
| 103_E | 108_V | 1.292 | 0.99 | |
| 178_Q | 181_E | 1.282 | 0.99 | |
| 34_Y | 80_I | 1.278 | 0.99 | |
| 37_R | 45_M | 1.276 | 0.99 | |
| 91_L | 134_P | 1.259 | 0.99 | |
| 73_V | 168_V | 1.243 | 0.98 | |
| 89_P | 186_D | 1.223 | 0.98 | |
| 130_F | 192_I | 1.22 | 0.98 | |
| 79_R | 93_E | 1.217 | 0.98 | |
| 21_R | 34_Y | 1.2 | 0.98 | |
| 133_S | 139_E | 1.198 | 0.98 | |
| 66_D | 119_L | 1.182 | 0.98 | |
| 105_V | 144_M | 1.18 | 0.98 | |
| 74_L | 171_V | 1.167 | 0.97 | |
| 82_A | 91_L | 1.16 | 0.97 | |
| 61_V | 141_S | 1.141 | 0.97 | |
| 32_D | 55_E | 1.14 | 0.97 | |
| 68_V | 71_E | 1.133 | 0.97 | |
| 131_L | 140_R | 1.126 | 0.97 | |
| 17_E | 37_R | 1.123 | 0.97 | |
| 24_L | 31_L | 1.119 | 0.96 | |
| 132_A | 136_G | 1.102 | 0.96 | |
| 110_R | 114_I | 1.09 | 0.96 | |
| 82_A | 89_P | 1.081 | 0.95 | |
| 70_D | 173_R | 1.079 | 0.95 | |
| 41_F | 165_D | 1.074 | 0.95 | |
| 143_I | 193_A | 1.073 | 0.95 | |
| 63_L | 197_L | 1.055 | 0.95 | |
| 171_V | 176_A | 1.053 | 0.95 | |
| 120_I | 150_A | 1.036 | 0.94 | |
| 56_R | 139_E | 1.036 | 0.94 | |
| 82_A | 131_L | 1.028 | 0.94 | |
| 176_A | 185_I | 1.027 | 0.94 | |
| 58_H | 99_I | 1.027 | 0.94 | |
| 130_F | 143_I | 1.023 | 0.93 | |
| 130_F | 191_V | 1.013 | 0.93 | |
| 176_A | 180_V | 1.012 | 0.93 | |
| 23_T | 30_S | 1.007 | 0.93 | |
| 33_L | 50_R | 1.003 | 0.93 | |
| 126_P | 144_M | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1g0sA | 2 | 1 | 100 | 0.261 | Contact Map | 0.861 |
| 2dscA | 2 | 0.9091 | 100 | 0.376 | Contact Map | 0.744 |
| 1vhzA | 2 | 0.8947 | 100 | 0.394 | Contact Map | 0.769 |
| 1mk1A | 1 | 0.89 | 100 | 0.421 | Contact Map | 0.784 |
| 3o6zA | 2 | 0.9091 | 100 | 0.428 | Contact Map | 0.834 |
| 2yvpA | 1 | 0.8517 | 100 | 0.472 | Contact Map | 0.765 |
| 1v8yA | 1 | 0.799 | 100 | 0.5 | Contact Map | 0.78 |
| 3q91A | 4 | 0.89 | 100 | 0.523 | Contact Map | 0.719 |
| 2w4eA | 2 | 0.6842 | 99.9 | 0.574 | Contact Map | 0.749 |
| 2fvvA | 1 | 0.8565 | 99.9 | 0.619 | Contact Map | 0.611 |
Sequence Conservation (Image Generated using WebLogo v3)