| UniProt: | P45799 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12926 | ||
| Length: | 186 (176) | ||
| Sequences: | 2663 | ||
| Seq/Len: | 15.13 |
| NUDE
Paralog alert: 0.40 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: ADPP NUDE NUDK |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 9_T | 30_E | 3.104 | 1.00 | |
| 51_M | 77_F | 3.036 | 1.00 | |
| 14_E | 26_S | 2.644 | 1.00 | |
| 106_D | 130_Q | 2.538 | 1.00 | |
| 105_N | 131_D | 2.535 | 1.00 | |
| 18_R | 23_T | 2.532 | 1.00 | |
| 89_Y | 93_N | 2.426 | 1.00 | |
| 75_L | 148_V | 2.408 | 1.00 | |
| 56_V | 59_H | 2.393 | 1.00 | |
| 87_S | 90_E | 2.327 | 1.00 | |
| 59_H | 151_P | 2.266 | 1.00 | |
| 108_T | 130_Q | 2.25 | 1.00 | |
| 155_M | 173_L | 2.236 | 1.00 | |
| 64_R | 146_P | 2.2 | 1.00 | |
| 157_D | 161_D | 2.178 | 1.00 | |
| 86_E | 94_R | 2.132 | 1.00 | |
| 59_H | 149_R | 2.111 | 1.00 | |
| 97_K | 103_G | 2.098 | 1.00 | |
| 88_V | 125_N | 2.081 | 1.00 | |
| 61_I | 149_R | 2.072 | 1.00 | |
| 65_E | 76_G | 2.064 | 1.00 | |
| 13_V | 25_E | 2.017 | 1.00 | |
| 154_H | 157_D | 1.908 | 1.00 | |
| 109_F | 125_N | 1.872 | 1.00 | |
| 112_K | 123_K | 1.851 | 1.00 | |
| 82_I | 91_A | 1.836 | 1.00 | |
| 52_I | 92_A | 1.835 | 1.00 | |
| 93_N | 107_L | 1.806 | 1.00 | |
| 109_F | 112_K | 1.764 | 1.00 | |
| 15_T | 18_R | 1.731 | 1.00 | |
| 151_P | 154_H | 1.718 | 1.00 | |
| 25_E | 43_R | 1.714 | 1.00 | |
| 27_V | 68_V | 1.71 | 1.00 | |
| 64_R | 148_V | 1.705 | 1.00 | |
| 112_K | 125_N | 1.698 | 1.00 | |
| 12_N | 28_D | 1.678 | 1.00 | |
| 106_D | 131_D | 1.672 | 1.00 | |
| 53_V | 172_A | 1.664 | 1.00 | |
| 150_W | 158_L | 1.661 | 1.00 | |
| 56_V | 149_R | 1.634 | 1.00 | |
| 158_L | 163_D | 1.606 | 1.00 | |
| 96_L | 104_A | 1.595 | 1.00 | |
| 13_V | 27_V | 1.579 | 1.00 | |
| 89_Y | 107_L | 1.572 | 1.00 | |
| 61_I | 102_F | 1.547 | 1.00 | |
| 43_R | 121_S | 1.537 | 1.00 | |
| 30_E | 36_R | 1.515 | 1.00 | |
| 110_L | 128_V | 1.497 | 1.00 | |
| 26_S | 40_E | 1.489 | 1.00 | |
| 105_N | 133_Y | 1.451 | 1.00 | |
| 114_S | 165_N | 1.442 | 1.00 | |
| 90_E | 93_N | 1.411 | 1.00 | |
| 77_F | 172_A | 1.394 | 0.99 | |
| 28_D | 38_V | 1.384 | 0.99 | |
| 91_A | 94_R | 1.377 | 0.99 | |
| 28_D | 36_R | 1.376 | 0.99 | |
| 10_I | 68_V | 1.365 | 0.99 | |
| 86_E | 91_A | 1.361 | 0.99 | |
| 116_A | 122_S | 1.338 | 0.99 | |
| 11_L | 30_E | 1.332 | 0.99 | |
| 74_E | 117_P | 1.29 | 0.99 | |
| 113_L | 171_S | 1.285 | 0.99 | |
| 88_V | 127_V | 1.274 | 0.99 | |
| 68_V | 71_E | 1.268 | 0.99 | |
| 97_K | 135_E | 1.212 | 0.98 | |
| 56_V | 102_F | 1.201 | 0.98 | |
| 61_I | 147_Q | 1.201 | 0.98 | |
| 26_S | 38_V | 1.195 | 0.98 | |
| 67_A | 76_G | 1.174 | 0.98 | |
| 32_S | 144_P | 1.132 | 0.97 | |
| 157_D | 160_E | 1.124 | 0.97 | |
| 58_D | 152_L | 1.109 | 0.96 | |
| 109_F | 127_V | 1.105 | 0.96 | |
| 70_T | 74_E | 1.096 | 0.96 | |
| 60_L | 77_F | 1.072 | 0.95 | |
| 15_T | 25_E | 1.071 | 0.95 | |
| 19_S | 40_E | 1.066 | 0.95 | |
| 53_V | 176_V | 1.066 | 0.95 | |
| 82_I | 88_V | 1.054 | 0.95 | |
| 114_S | 123_K | 1.053 | 0.95 | |
| 93_N | 97_K | 1.046 | 0.94 | |
| 16_V | 24_V | 1.035 | 0.94 | |
| 155_M | 159_L | 1.033 | 0.94 | |
| 72_S | 165_N | 1.022 | 0.93 | |
| 113_L | 170_V | 1.017 | 0.93 | |
| 57_D | 131_D | 1.015 | 0.93 | |
| 156_M | 160_E | 1.013 | 0.93 | |
| 115_M | 119_Y | 1.005 | 0.93 | |
| 159_L | 170_V | 1.004 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1vhzA | 2 | 1 | 100 | 0.278 | Contact Map | 0.785 |
| 1g0sA | 2 | 0.9839 | 100 | 0.3 | Contact Map | 0.848 |
| 2dscA | 2 | 0.9785 | 100 | 0.321 | Contact Map | 0.802 |
| 1mk1A | 1 | 0.9785 | 100 | 0.361 | Contact Map | 0.792 |
| 2yvpA | 1 | 0.9624 | 100 | 0.392 | Contact Map | 0.784 |
| 3o6zA | 2 | 0.9301 | 100 | 0.418 | Contact Map | 0.822 |
| 1v8yA | 1 | 0.9086 | 100 | 0.435 | Contact Map | 0.787 |
| 3q91A | 4 | 0.9301 | 99.9 | 0.504 | Contact Map | 0.731 |
| 2w4eA | 2 | 0.7742 | 99.9 | 0.516 | Contact Map | 0.73 |
| 2fvvA | 1 | 0.9355 | 99.9 | 0.568 | Contact Map | 0.616 |
Sequence Conservation (Image Generated using WebLogo v3)