| UniProt: | Q6BF16 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11716 | ||
| Length: | 205 (198) | ||
| Sequences: | 1543 | ||
| Seq/Len: | 7.79 |
| DGOA
Paralog alert: 0.43 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: ALKH DGOA |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 53_V | 82_Q | 3.61 | 1.00 | |
| 27_A | 31_A | 2.51 | 1.00 | |
| 47_Q | 50_P | 2.376 | 1.00 | |
| 90_H | 119_E | 2.194 | 1.00 | |
| 91_S | 116_T | 2.155 | 1.00 | |
| 17_T | 20_E | 2.145 | 1.00 | |
| 26_G | 55_A | 2.112 | 1.00 | |
| 190_A | 194_A | 2.074 | 1.00 | |
| 69_K | 72_Q | 2.051 | 1.00 | |
| 40_L | 46_E | 2.041 | 1.00 | |
| 117_A | 125_L | 2.027 | 1.00 | |
| 25_V | 52_I | 1.988 | 1.00 | |
| 77_A | 102_M | 1.963 | 1.00 | |
| 30_D | 190_A | 1.936 | 1.00 | |
| 50_P | 54_D | 1.933 | 1.00 | |
| 94_I | 104_V | 1.93 | 1.00 | |
| 185_S | 188_R | 1.917 | 1.00 | |
| 110_T | 113_E | 1.916 | 1.00 | |
| 74_D | 96_R | 1.905 | 1.00 | |
| 46_E | 75_A | 1.834 | 1.00 | |
| 74_D | 78_R | 1.82 | 1.00 | |
| 163_A | 167_D | 1.784 | 1.00 | |
| 85_V | 105_C | 1.775 | 1.00 | |
| 89_I | 120_A | 1.764 | 1.00 | |
| 10_I | 152_F | 1.76 | 1.00 | |
| 71_E | 75_A | 1.75 | 1.00 | |
| 13_L | 36_V | 1.733 | 1.00 | |
| 95_R | 120_A | 1.725 | 1.00 | |
| 72_Q | 75_A | 1.722 | 1.00 | |
| 133_F | 137_Y | 1.715 | 1.00 | |
| 49_I | 64_A | 1.691 | 1.00 | |
| 118_L | 148_D | 1.669 | 1.00 | |
| 67_V | 84_I | 1.631 | 1.00 | |
| 108_C | 114_A | 1.628 | 1.00 | |
| 18_P | 44_Q | 1.622 | 1.00 | |
| 114_A | 149_I | 1.618 | 1.00 | |
| 191_Q | 195_A | 1.609 | 1.00 | |
| 118_L | 149_I | 1.565 | 1.00 | |
| 92_E | 119_E | 1.563 | 1.00 | |
| 137_Y | 141_L | 1.54 | 1.00 | |
| 98_V | 123_Q | 1.534 | 1.00 | |
| 108_C | 125_L | 1.527 | 1.00 | |
| 29_I | 56_Y | 1.48 | 0.99 | |
| 127_I | 133_F | 1.447 | 0.99 | |
| 188_R | 192_Q | 1.44 | 0.99 | |
| 96_R | 100_Y | 1.433 | 0.99 | |
| 22_L | 56_Y | 1.42 | 0.99 | |
| 89_I | 94_I | 1.399 | 0.99 | |
| 109_A | 133_F | 1.398 | 0.99 | |
| 38_I | 52_I | 1.382 | 0.99 | |
| 188_R | 191_Q | 1.382 | 0.99 | |
| 86_T | 104_V | 1.372 | 0.99 | |
| 22_L | 51_A | 1.368 | 0.99 | |
| 111_A | 141_L | 1.344 | 0.99 | |
| 97_A | 104_V | 1.344 | 0.99 | |
| 47_Q | 51_A | 1.33 | 0.98 | |
| 29_I | 60_A | 1.316 | 0.98 | |
| 44_Q | 47_Q | 1.305 | 0.98 | |
| 74_D | 100_Y | 1.296 | 0.98 | |
| 89_I | 108_C | 1.292 | 0.98 | |
| 22_L | 55_A | 1.288 | 0.98 | |
| 26_G | 30_D | 1.254 | 0.98 | |
| 40_L | 76_L | 1.243 | 0.97 | |
| 73_V | 93_V | 1.232 | 0.97 | |
| 63_G | 83_L | 1.228 | 0.97 | |
| 131_S | 165_W | 1.199 | 0.97 | |
| 112_T | 116_T | 1.193 | 0.96 | |
| 88_N | 115_F | 1.193 | 0.96 | |
| 84_I | 97_A | 1.19 | 0.96 | |
| 84_I | 102_M | 1.186 | 0.96 | |
| 127_I | 151_V | 1.186 | 0.96 | |
| 131_S | 136_Q | 1.152 | 0.95 | |
| 138_I | 170_C | 1.151 | 0.95 | |
| 76_L | 81_C | 1.149 | 0.95 | |
| 92_E | 95_R | 1.145 | 0.95 | |
| 189_T | 193_A | 1.142 | 0.95 | |
| 29_I | 34_D | 1.133 | 0.95 | |
| 153_A | 170_C | 1.127 | 0.95 | |
| 86_T | 106_P | 1.127 | 0.95 | |
| 51_A | 55_A | 1.118 | 0.94 | |
| 158_T | 161_N | 1.115 | 0.94 | |
| 64_A | 76_L | 1.104 | 0.94 | |
| 6_K | 61_L | 1.101 | 0.94 | |
| 22_L | 52_I | 1.1 | 0.94 | |
| 75_A | 78_R | 1.093 | 0.93 | |
| 26_G | 56_Y | 1.092 | 0.93 | |
| 73_V | 97_A | 1.089 | 0.93 | |
| 114_A | 145_L | 1.076 | 0.93 | |
| 175_L | 178_D | 1.072 | 0.92 | |
| 73_V | 96_R | 1.069 | 0.92 | |
| 95_R | 99_G | 1.066 | 0.92 | |
| 91_S | 95_R | 1.061 | 0.92 | |
| 166_I | 203_A | 1.058 | 0.92 | |
| 153_A | 171_A | 1.052 | 0.92 | |
| 94_I | 122_A | 1.044 | 0.91 | |
| 132_A | 137_Y | 1.042 | 0.91 | |
| 198_K | 202_E | 1.038 | 0.91 | |
| 41_N | 154_V | 1.037 | 0.91 | |
| 109_A | 137_Y | 1.036 | 0.91 | |
| 104_V | 122_A | 1.035 | 0.91 | |
| 194_A | 198_K | 1.032 | 0.91 | |
| 178_D | 196_F | 1.029 | 0.90 | |
| 18_P | 48_S | 1.029 | 0.90 | |
| 99_G | 119_E | 1.025 | 0.90 | |
| 73_V | 84_I | 1.019 | 0.90 | |
| 68_L | 148_D | 1.011 | 0.89 | |
| 70_P | 96_R | 1.005 | 0.89 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 4e38A | 3 | 0.9756 | 100 | 0.479 | Contact Map | 0.808 |
| 1vhcA | 6 | 0.9902 | 100 | 0.482 | Contact Map | 0.808 |
| 3labA | 2 | 0.9756 | 100 | 0.486 | Contact Map | 0.675 |
| 2yw3A | 6 | 0.9707 | 100 | 0.492 | Contact Map | 0.692 |
| 1wbhA | 3 | 0.9756 | 100 | 0.494 | Contact Map | 0.765 |
| 1mxsA | 1 | 0.9805 | 100 | 0.497 | Contact Map | 0.677 |
| 1wa3A | 6 | 0.9854 | 100 | 0.521 | Contact Map | 0.835 |
| 2v82A | 1 | 1 | 100 | 0.56 | Contact Map | 0.65 |
| 1w8sA | 10 | 0.9415 | 99.9 | 0.653 | Contact Map | 0.384 |
| 3nl6A | 3 | 0.9463 | 99.9 | 0.656 | Contact Map | 0.406 |
Sequence Conservation (Image Generated using WebLogo v3)