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YAJL - Chaperone protein YajL
UniProt: Q46948 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13272
Length: 196 (185)
Sequences: 6679
Seq/Len: 36.10

YAJL
Paralog alert: 0.64 [within 20: 0.10] - ratio of genomes with paralogs
Cluster includes: YAJL YHBO
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
123_N 138_Q 2.851 1.00
146_W 171_L 2.847 1.00
4_S 31_K 2.835 1.00
123_N 140_L 2.738 1.00
122_G 148_A 2.662 1.00
167_K 170_D 2.637 1.00
6_L 35_A 2.587 1.00
33_T 67_Y 2.463 1.00
120_P 136_A 2.415 1.00
6_L 67_Y 2.358 1.00
24_L 169_I 2.295 1.00
122_G 147_D 2.191 1.00
119_F 124_M 2.054 1.00
33_T 57_A 1.938 1.00
175_R 179_H 1.812 1.00
44_A 54_L 1.812 1.00
124_M 137_E 1.809 1.00
4_S 33_T 1.791 1.00
38_A 43_L 1.783 1.00
148_A 151_K 1.742 1.00
96_H 102_V 1.709 1.00
122_G 152_L 1.699 1.00
114_V 137_E 1.687 1.00
134_I 139_W 1.669 1.00
36_S 39_S 1.657 1.00
146_W 167_K 1.622 1.00
58_P 61_E 1.617 1.00
104_A 154_T 1.612 1.00
13_S 47_C 1.599 1.00
90_E 93_K 1.544 1.00
28_G 169_I 1.539 1.00
153_L 171_L 1.538 1.00
60_V 87_L 1.535 1.00
96_H 151_K 1.513 1.00
5_A 69_V 1.51 1.00
170_D 175_R 1.507 1.00
22_I 26_V 1.485 1.00
122_G 151_K 1.474 1.00
123_N 147_D 1.473 1.00
95_F 100_R 1.473 1.00
15_E 19_V 1.423 1.00
94_Q 98_S 1.421 1.00
30_I 172_L 1.403 0.99
11_P 46_T 1.358 0.99
101_I 171_L 1.35 0.99
44_A 52_K 1.341 0.99
142_K 163_D 1.334 0.99
155_S 160_T 1.315 0.99
96_H 152_L 1.308 0.99
9_L 18_A 1.304 0.99
93_K 97_R 1.287 0.99
13_S 18_A 1.284 0.99
37_V 85_S 1.283 0.99
7_V 22_I 1.283 0.99
96_H 118_I 1.281 0.99
86_T 90_E 1.276 0.99
90_E 94_Q 1.274 0.99
89_V 93_K 1.26 0.99
143_R 163_D 1.257 0.99
63_A 66_E 1.248 0.99
16_T 20_T 1.236 0.98
8_C 88_L 1.234 0.98
134_I 137_E 1.234 0.98
69_V 101_I 1.219 0.98
89_V 116_H 1.217 0.98
64_D 94_Q 1.214 0.98
99_G 151_K 1.214 0.98
146_W 153_L 1.212 0.98
87_L 90_E 1.207 0.98
9_L 34_T 1.197 0.98
173_V 177_K 1.194 0.98
68_D 100_R 1.194 0.98
25_L 165_G 1.182 0.98
46_T 52_K 1.178 0.98
177_K 180_E 1.171 0.98
5_A 30_I 1.161 0.97
109_P 126_G 1.149 0.97
18_A 34_T 1.148 0.97
20_T 162_I 1.146 0.97
131_K 135_P 1.145 0.97
52_K 56_D 1.144 0.97
104_A 113_L 1.141 0.97
13_S 53_L 1.131 0.97
22_I 34_T 1.13 0.97
117_D 120_P 1.121 0.97
176_E 180_E 1.109 0.96
7_V 71_V 1.109 0.96
178_A 182_A 1.108 0.96
167_K 171_L 1.103 0.96
128_P 139_W 1.102 0.96
94_Q 97_R 1.098 0.96
9_L 13_S 1.095 0.96
36_S 55_A 1.088 0.96
101_I 172_L 1.084 0.96
99_G 102_V 1.082 0.96
91_T 95_F 1.081 0.95
69_V 172_L 1.064 0.95
23_D 27_R 1.055 0.95
103_A 168_I 1.054 0.95
104_A 109_P 1.051 0.94
20_T 23_D 1.032 0.94
153_L 164_F 1.024 0.93
44_A 55_A 1.017 0.93
23_D 26_V 1.012 0.93
144_V 167_K 1.006 0.93
24_L 185_L 1.003 0.93
75_G 78_G 1.001 0.92
15_E 51_V 1.001 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2ab0A20.99491000.091Contact Map0.735
4k2hA140.93881000.094Contact Map0.722
3ewnA10.96431000.116Contact Map0.754
3noqA20.9491000.118Contact Map0.711
2rk3A10.97451000.118Contact Map0.746
3graA20.9491000.121Contact Map0.699
3mgkA20.95411000.122Contact Map0.723
3ot1A10.97961000.127Contact Map0.733
4e08A20.94391000.127Contact Map0.808
3er6A60.95411000.133Contact Map0.744

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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