| UniProt: | Q46908 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13125 | ||
| Length: | 259 (250) | ||
| Sequences: | 1677 | ||
| Seq/Len: | 6.71 |
| YGCR
Paralog alert: 0.38 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: FIXA YDIQ YGCR |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 77_L | 88_A | 4.12 | 1.00 | |
| 159_F | 174_R | 4.028 | 1.00 | |
| 135_P | 182_A | 3.781 | 1.00 | |
| 62_S | 87_E | 3.68 | 1.00 | |
| 240_T | 243_E | 3.569 | 1.00 | |
| 110_E | 113_H | 3.149 | 1.00 | |
| 147_F | 175_V | 2.779 | 1.00 | |
| 50_L | 53_A | 2.613 | 1.00 | |
| 65_A | 80_L | 2.583 | 1.00 | |
| 152_R | 163_E | 2.525 | 1.00 | |
| 91_L | 107_H | 2.486 | 1.00 | |
| 55_R | 86_E | 2.448 | 1.00 | |
| 87_E | 210_K | 2.376 | 1.00 | |
| 114_Q | 212_V | 2.373 | 1.00 | |
| 81_M | 88_A | 2.277 | 1.00 | |
| 109_A | 113_H | 2.244 | 1.00 | |
| 40_L | 76_W | 2.217 | 1.00 | |
| 2_N | 62_S | 2.208 | 1.00 | |
| 160_I | 175_V | 2.194 | 1.00 | |
| 150_V | 181_I | 2.072 | 1.00 | |
| 120_I | 144_W | 2.057 | 1.00 | |
| 161_T | 174_R | 1.914 | 1.00 | |
| 105_A | 141_M | 1.912 | 1.00 | |
| 67_S | 73_A | 1.869 | 1.00 | |
| 155_L | 160_I | 1.855 | 1.00 | |
| 159_F | 176_R | 1.854 | 1.00 | |
| 122_T | 138_L | 1.847 | 1.00 | |
| 125_Q | 130_Q | 1.845 | 1.00 | |
| 3_I | 60_P | 1.84 | 1.00 | |
| 92_E | 211_T | 1.824 | 1.00 | |
| 154_T | 161_T | 1.814 | 1.00 | |
| 108_I | 138_L | 1.784 | 1.00 | |
| 175_V | 179_A | 1.744 | 1.00 | |
| 112_Q | 120_I | 1.739 | 1.00 | |
| 153_F | 160_I | 1.732 | 1.00 | |
| 70_D | 73_A | 1.716 | 1.00 | |
| 4_L | 112_Q | 1.692 | 1.00 | |
| 118_D | 158_L | 1.689 | 1.00 | |
| 150_V | 162_L | 1.671 | 1.00 | |
| 64_T | 87_E | 1.659 | 1.00 | |
| 119_L | 179_A | 1.65 | 1.00 | |
| 156_D | 161_T | 1.639 | 1.00 | |
| 48_A | 85_F | 1.627 | 1.00 | |
| 49_A | 192_P | 1.623 | 1.00 | |
| 74_L | 78_R | 1.62 | 1.00 | |
| 195_G | 198_Q | 1.597 | 1.00 | |
| 206_E | 210_K | 1.584 | 1.00 | |
| 241_V | 245_A | 1.56 | 0.99 | |
| 41_G | 44_E | 1.543 | 0.99 | |
| 64_T | 89_V | 1.539 | 0.99 | |
| 63_L | 85_F | 1.535 | 0.99 | |
| 6_A | 122_T | 1.534 | 0.99 | |
| 65_A | 85_F | 1.529 | 0.99 | |
| 161_T | 172_C | 1.526 | 0.99 | |
| 73_A | 90_L | 1.514 | 0.99 | |
| 57_N | 154_T | 1.5 | 0.99 | |
| 74_L | 211_T | 1.499 | 0.99 | |
| 230_R | 233_A | 1.494 | 0.99 | |
| 56_K | 192_P | 1.473 | 0.99 | |
| 238_G | 243_E | 1.471 | 0.99 | |
| 71_E | 92_E | 1.462 | 0.99 | |
| 164_Q | 171_R | 1.43 | 0.99 | |
| 160_I | 177_L | 1.412 | 0.99 | |
| 66_L | 111_W | 1.406 | 0.99 | |
| 145_P | 179_A | 1.403 | 0.99 | |
| 93_T | 98_R | 1.373 | 0.98 | |
| 114_Q | 210_K | 1.372 | 0.98 | |
| 242_A | 245_A | 1.342 | 0.98 | |
| 45_Q | 83_L | 1.338 | 0.98 | |
| 147_F | 173_C | 1.325 | 0.98 | |
| 60_P | 63_L | 1.322 | 0.98 | |
| 67_S | 90_L | 1.308 | 0.98 | |
| 2_N | 64_T | 1.3 | 0.97 | |
| 110_E | 114_Q | 1.297 | 0.97 | |
| 91_L | 111_W | 1.249 | 0.97 | |
| 32_D | 35_L | 1.243 | 0.96 | |
| 163_E | 172_C | 1.209 | 0.96 | |
| 158_L | 176_R | 1.204 | 0.96 | |
| 50_L | 152_R | 1.203 | 0.95 | |
| 4_L | 117_L | 1.199 | 0.95 | |
| 111_W | 212_V | 1.194 | 0.95 | |
| 107_H | 111_W | 1.185 | 0.95 | |
| 92_E | 213_A | 1.17 | 0.95 | |
| 77_L | 90_L | 1.169 | 0.94 | |
| 183_V | 187_G | 1.163 | 0.94 | |
| 96_D | 100_A | 1.149 | 0.94 | |
| 109_A | 142_L | 1.137 | 0.93 | |
| 139_A | 146_C | 1.133 | 0.93 | |
| 199_R | 205_A | 1.133 | 0.93 | |
| 40_L | 80_L | 1.132 | 0.93 | |
| 44_E | 131_N | 1.13 | 0.93 | |
| 74_L | 207_I | 1.12 | 0.93 | |
| 156_D | 159_F | 1.119 | 0.93 | |
| 51_L | 63_L | 1.113 | 0.92 | |
| 154_T | 163_E | 1.108 | 0.92 | |
| 43_D | 124_C | 1.108 | 0.92 | |
| 88_A | 207_I | 1.104 | 0.92 | |
| 197_R | 201_A | 1.084 | 0.91 | |
| 52_L | 83_L | 1.082 | 0.91 | |
| 7_F | 76_W | 1.08 | 0.91 | |
| 52_L | 198_Q | 1.078 | 0.91 | |
| 243_E | 246_Q | 1.076 | 0.91 | |
| 89_V | 111_W | 1.073 | 0.90 | |
| 64_T | 117_L | 1.055 | 0.89 | |
| 151_E | 163_E | 1.048 | 0.89 | |
| 89_V | 212_V | 1.038 | 0.88 | |
| 144_W | 180_V | 1.033 | 0.88 | |
| 234_T | 251_D | 1.032 | 0.88 | |
| 112_Q | 117_L | 1.03 | 0.88 | |
| 202_A | 205_A | 1.025 | 0.88 | |
| 121_I | 183_V | 1.024 | 0.88 | |
| 163_E | 170_L | 1.022 | 0.87 | |
| 50_L | 188_E | 1.022 | 0.87 | |
| 13_A | 39_L | 1.02 | 0.87 | |
| 7_F | 80_L | 1.018 | 0.87 | |
| 193_V | 199_R | 1.014 | 0.87 | |
| 112_Q | 138_L | 1.013 | 0.87 | |
| 160_I | 181_I | 1.002 | 0.86 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1o97C | 1 | 0.9537 | 100 | 0.236 | Contact Map | 0.749 |
| 1efpB | 2 | 0.9421 | 100 | 0.261 | Contact Map | 0.754 |
| 1efvB | 1 | 0.9421 | 100 | 0.281 | Contact Map | 0.807 |
| 3ih5A | 4 | 0.7452 | 100 | 0.642 | Contact Map | 0.638 |
| 1o97D | 1 | 0.8301 | 100 | 0.643 | Contact Map | 0.537 |
| 1efpA | 2 | 0.7992 | 99.9 | 0.682 | Contact Map | 0.61 |
| 1efvA | 1 | 0.8224 | 99.9 | 0.684 | Contact Map | 0.719 |
| 3fetA | 4 | 0.6332 | 99.9 | 0.692 | Contact Map | 0.626 |
| 3idfA | 2 | 0.4324 | 90.3 | 0.933 | Contact Map | 0.56 |
| 3hgmA | 4 | 0.4363 | 89.8 | 0.933 | Contact Map | 0.599 |
Sequence Conservation (Image Generated using WebLogo v3)