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OPENSEQ.org

YDIQ - Putative electron transfer flavoprotein subunit YdiQ
UniProt: P76201 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13976
Length: 254 (249)
Sequences: 1717
Seq/Len: 6.90

YDIQ
Paralog alert: 0.38 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: FIXA YDIQ YGCR
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
70_R 81_L 4.062 1.00
152_T 167_E 3.782 1.00
128_G 175_C 3.585 1.00
53_E 80_S 3.548 1.00
103_A 106_E 2.991 1.00
43_A 46_Q 2.721 1.00
140_I 168_L 2.667 1.00
203_Q 206_D 2.528 1.00
48_A 79_H 2.509 1.00
107_K 202_W 2.482 1.00
56_A 73_V 2.466 1.00
145_A 156_E 2.396 1.00
237_D 240_E 2.371 1.00
80_S 200_N 2.363 1.00
84_V 100_A 2.353 1.00
74_L 81_L 2.23 1.00
102_A 106_E 2.179 1.00
43_A 181_N 2.153 1.00
153_L 168_L 2.085 1.00
113_L 137_L 2.028 1.00
33_I 69_V 2.003 1.00
2_K 53_E 1.972 1.00
98_A 134_I 1.959 1.00
143_V 174_L 1.946 1.00
58_T 64_L 1.917 1.00
105_I 113_L 1.871 1.00
154_V 167_E 1.861 1.00
118_G 123_Y 1.83 1.00
85_Q 201_Q 1.811 1.00
152_T 169_S 1.807 1.00
101_L 131_V 1.802 1.00
115_F 131_V 1.773 1.00
168_L 172_A 1.76 1.00
176_V 180_I 1.742 1.00
148_R 153_L 1.72 1.00
61_G 64_L 1.672 1.00
112_L 172_A 1.669 1.00
236_N 240_E 1.648 1.00
55_A 80_S 1.645 1.00
41_I 78_P 1.627 1.00
187_S 190_A 1.617 1.00
4_I 105_I 1.611 1.00
143_V 155_I 1.609 1.00
107_K 200_N 1.6 1.00
202_W 207_I 1.596 1.00
111_D 151_N 1.575 1.00
146_I 153_L 1.567 1.00
247_E 251_K 1.562 1.00
6_C 115_F 1.555 1.00
49_T 184_R 1.549 0.99
92_A 100_A 1.537 0.99
147_Q 154_V 1.534 0.99
42_E 184_R 1.526 0.99
56_A 78_P 1.519 0.99
55_A 82_Y 1.492 0.99
65_Q 71_K 1.476 0.99
34_S 37_D 1.468 0.99
62_S 85_Q 1.466 0.99
204_A 211_Q 1.466 0.99
154_V 165_V 1.465 0.99
64_L 83_L 1.46 0.99
65_Q 201_Q 1.435 0.99
54_I 78_P 1.42 0.99
157_R 164_E 1.418 0.99
50_D 147_Q 1.408 0.99
38_L 76_R 1.399 0.99
153_L 170_V 1.37 0.98
107_K 207_I 1.367 0.98
57_L 104_A 1.338 0.98
25_N 28_N 1.333 0.98
238_S 242_I 1.331 0.98
58_T 83_L 1.311 0.98
2_K 55_A 1.303 0.98
138_P 172_A 1.287 0.97
140_I 166_I 1.213 0.96
39_N 181_N 1.206 0.96
156_E 165_V 1.202 0.96
86_D 91_H 1.2 0.96
102_A 135_L 1.197 0.96
151_N 169_S 1.196 0.96
84_V 104_A 1.182 0.95
43_A 145_A 1.173 0.95
132_G 139_V 1.153 0.94
100_A 104_A 1.152 0.94
149_Q 154_V 1.151 0.94
33_I 73_V 1.142 0.94
191_I 197_K 1.131 0.93
103_A 107_K 1.128 0.93
45_S 76_R 1.123 0.93
4_I 110_F 1.119 0.93
104_A 202_W 1.117 0.93
105_I 110_F 1.112 0.93
36_F 117_E 1.11 0.93
149_Q 152_T 1.096 0.92
45_S 190_A 1.076 0.91
240_E 244_E 1.074 0.91
56_A 70_R 1.067 0.91
102_A 131_V 1.063 0.90
137_L 173_V 1.059 0.90
74_L 197_K 1.058 0.90
93_L 214_P 1.054 0.90
55_A 108_I 1.049 0.90
43_A 50_D 1.047 0.89
65_Q 199_V 1.046 0.89
144_S 156_E 1.045 0.89
156_E 163_V 1.04 0.89
232_I 248_H 1.035 0.89
82_Y 202_W 1.023 0.88
105_I 131_V 1.016 0.87
185_I 191_I 1.007 0.87
114_I 176_V 1.006 0.87
59_V 92_A 1 0.86
55_A 110_F 1 0.86
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1o97C10.98031000.212Contact Map0.787
1efpB20.96061000.235Contact Map0.788
1efvB10.96461000.257Contact Map0.824
1o97D10.83071000.635Contact Map0.536
3ih5A40.77951000.636Contact Map0.639
1efvA10.826899.90.667Contact Map0.702
1efpA20.807199.90.672Contact Map0.599
3fetA40.645799.90.698Contact Map0.626
3idfA20.43790.60.932Contact Map0.539
3hgmA40.448890.60.932Contact Map0.604

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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