| UniProt: | Q46907 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13124 | ||
| Length: | 286 (244) | ||
| Sequences: | 1679 | ||
| Seq/Len: | 6.88 |
| YGCQ
Paralog alert: 0.43 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: FIXB YDIR YGCQ |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 268_D | 273_V | 5.846 | 1.00 | |
| 259_F | 265_G | 4.173 | 1.00 | |
| 229_V | 250_I | 3.785 | 1.00 | |
| 169_R | 224_E | 3.308 | 1.00 | |
| 173_V | 231_A | 3.155 | 1.00 | |
| 171_V | 221_L | 3.041 | 1.00 | |
| 62_F | 72_S | 2.898 | 1.00 | |
| 174_V | 182_N | 2.784 | 1.00 | |
| 199_S | 231_A | 2.571 | 1.00 | |
| 229_V | 274_L | 2.464 | 1.00 | |
| 208_V | 212_K | 2.213 | 1.00 | |
| 188_L | 278_V | 2.199 | 1.00 | |
| 188_L | 274_L | 2.153 | 1.00 | |
| 221_L | 241_V | 2.136 | 1.00 | |
| 187_M | 278_V | 2.124 | 1.00 | |
| 246_F | 264_V | 2.104 | 1.00 | |
| 198_Y | 208_V | 2.103 | 1.00 | |
| 191_K | 278_V | 2.097 | 1.00 | |
| 225_V | 248_V | 2.059 | 1.00 | |
| 183_Q | 186_A | 2.027 | 1.00 | |
| 173_V | 214_I | 2.019 | 1.00 | |
| 186_A | 196_V | 2.011 | 1.00 | |
| 182_N | 196_V | 1.993 | 1.00 | |
| 174_V | 185_I | 1.95 | 1.00 | |
| 185_I | 229_V | 1.946 | 1.00 | |
| 98_R | 107_T | 1.945 | 1.00 | |
| 89_S | 98_R | 1.929 | 1.00 | |
| 276_A | 279_T | 1.926 | 1.00 | |
| 249_A | 262_A | 1.916 | 1.00 | |
| 226_C | 237_L | 1.899 | 1.00 | |
| 229_V | 270_W | 1.88 | 1.00 | |
| 241_V | 244_S | 1.874 | 1.00 | |
| 124_Q | 127_A | 1.865 | 1.00 | |
| 172_L | 188_L | 1.859 | 1.00 | |
| 170_R | 194_A | 1.843 | 1.00 | |
| 171_V | 197_G | 1.801 | 1.00 | |
| 88_T | 107_T | 1.785 | 1.00 | |
| 183_Q | 187_M | 1.768 | 1.00 | |
| 181_D | 271_K | 1.754 | 1.00 | |
| 249_A | 258_V | 1.749 | 1.00 | |
| 87_V | 90_L | 1.748 | 1.00 | |
| 187_M | 191_K | 1.743 | 1.00 | |
| 188_L | 192_L | 1.717 | 1.00 | |
| 173_V | 228_V | 1.716 | 1.00 | |
| 177_G | 207_G | 1.715 | 1.00 | |
| 238_M | 261_Q | 1.684 | 1.00 | |
| 84_I | 87_V | 1.683 | 1.00 | |
| 88_T | 98_R | 1.645 | 1.00 | |
| 165_L | 171_V | 1.623 | 1.00 | |
| 198_Y | 202_R | 1.606 | 1.00 | |
| 228_V | 231_A | 1.566 | 1.00 | |
| 181_D | 184_E | 1.527 | 0.99 | |
| 84_I | 112_T | 1.522 | 0.99 | |
| 184_E | 274_L | 1.509 | 0.99 | |
| 124_Q | 129_K | 1.485 | 0.99 | |
| 224_E | 245_K | 1.482 | 0.99 | |
| 275_E | 278_V | 1.477 | 0.99 | |
| 178_G | 185_I | 1.474 | 0.99 | |
| 186_A | 190_E | 1.414 | 0.99 | |
| 228_V | 237_L | 1.413 | 0.99 | |
| 165_L | 197_G | 1.394 | 0.99 | |
| 177_G | 181_D | 1.388 | 0.99 | |
| 197_G | 214_I | 1.366 | 0.98 | |
| 164_P | 167_E | 1.365 | 0.98 | |
| 178_G | 181_D | 1.365 | 0.98 | |
| 101_H | 106_L | 1.353 | 0.98 | |
| 198_Y | 203_V | 1.34 | 0.98 | |
| 184_E | 187_M | 1.329 | 0.98 | |
| 209_D | 212_K | 1.306 | 0.98 | |
| 274_L | 278_V | 1.278 | 0.97 | |
| 190_E | 193_G | 1.251 | 0.97 | |
| 173_V | 199_S | 1.247 | 0.97 | |
| 178_G | 270_W | 1.243 | 0.97 | |
| 96_S | 109_T | 1.235 | 0.96 | |
| 203_V | 213_V | 1.232 | 0.96 | |
| 182_N | 202_R | 1.223 | 0.96 | |
| 266_V | 273_V | 1.213 | 0.96 | |
| 177_G | 184_E | 1.202 | 0.96 | |
| 222_A | 243_N | 1.199 | 0.96 | |
| 87_V | 119_L | 1.191 | 0.95 | |
| 184_E | 278_V | 1.188 | 0.95 | |
| 170_R | 227_I | 1.179 | 0.95 | |
| 179_E | 271_K | 1.165 | 0.95 | |
| 141_N | 144_P | 1.159 | 0.94 | |
| 178_G | 207_G | 1.153 | 0.94 | |
| 94_T | 111_Q | 1.135 | 0.94 | |
| 259_F | 267_V | 1.133 | 0.93 | |
| 91_D | 98_R | 1.118 | 0.93 | |
| 272_V | 276_A | 1.118 | 0.93 | |
| 199_S | 228_V | 1.11 | 0.93 | |
| 185_I | 196_V | 1.107 | 0.92 | |
| 228_V | 258_V | 1.107 | 0.92 | |
| 174_V | 202_R | 1.104 | 0.92 | |
| 250_I | 273_V | 1.101 | 0.92 | |
| 75_L | 118_C | 1.083 | 0.91 | |
| 276_A | 280_N | 1.072 | 0.91 | |
| 183_Q | 272_V | 1.07 | 0.91 | |
| 182_N | 185_I | 1.066 | 0.90 | |
| 60_V | 79_L | 1.063 | 0.90 | |
| 51_Q | 54_R | 1.05 | 0.90 | |
| 115_R | 119_L | 1.048 | 0.89 | |
| 173_V | 221_L | 1.045 | 0.89 | |
| 166_A | 219_H | 1.033 | 0.89 | |
| 46_D | 50_E | 1.012 | 0.87 | |
| 216_I | 234_A | 1.008 | 0.87 | |
| 118_C | 121_L | 1.005 | 0.87 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1o97D | 1 | 0.951 | 100 | 0.176 | Contact Map | 0.75 |
| 1efvA | 1 | 0.9825 | 100 | 0.178 | Contact Map | 0.838 |
| 1efpA | 2 | 0.9441 | 100 | 0.184 | Contact Map | 0.825 |
| 3ih5A | 4 | 0.5734 | 99.7 | 0.808 | Contact Map | 0.781 |
| 3fetA | 4 | 0.5175 | 99.6 | 0.826 | Contact Map | 0.806 |
| 1o97C | 1 | 0.6399 | 99.3 | 0.849 | Contact Map | 0.647 |
| 1efpB | 2 | 0.6014 | 99.3 | 0.851 | Contact Map | 0.662 |
| 1efvB | 1 | 0.6154 | 99.3 | 0.852 | Contact Map | 0.715 |
| 4kgdA | 2 | 0.9371 | 93.7 | 0.938 | Contact Map | 0.702 |
| 1ozhA | 4 | 0.9161 | 92.9 | 0.939 | Contact Map | 0.686 |
Sequence Conservation (Image Generated using WebLogo v3)