| UniProt: | Q46822 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13072 | ||
| Length: | 182 (167) | ||
| Sequences: | 1094 | ||
| Seq/Len: | 6.55 |
| IDI
Paralog alert: 0.43 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: IDI YFCD |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 10_N | 14_V | 6.438 | 1.00 | |
| 41_N | 45_Q | 5.712 | 1.00 | |
| 42_A | 126_T | 3.995 | 1.00 | |
| 53_L | 60_G | 3.971 | 1.00 | |
| 50_R | 138_D | 3.531 | 1.00 | |
| 142_C | 147_V | 2.805 | 1.00 | |
| 53_L | 137_M | 2.506 | 1.00 | |
| 40_F | 46_L | 2.389 | 1.00 | |
| 13_G | 33_L | 2.35 | 1.00 | |
| 37_S | 80_V | 2.261 | 1.00 | |
| 50_R | 137_M | 2.128 | 1.00 | |
| 150_G | 158_F | 2.018 | 1.00 | |
| 66_V | 84_C | 1.957 | 1.00 | |
| 100_P | 120_V | 1.916 | 1.00 | |
| 85_R | 91_E | 1.82 | 1.00 | |
| 47_L | 139_Y | 1.764 | 1.00 | |
| 25_H | 116_E | 1.758 | 1.00 | |
| 83_R | 86_Y | 1.752 | 1.00 | |
| 9_L | 33_L | 1.696 | 1.00 | |
| 19_L | 24_A | 1.619 | 1.00 | |
| 143_D | 146_D | 1.607 | 1.00 | |
| 58_W | 160_P | 1.604 | 1.00 | |
| 69_H | 116_E | 1.581 | 1.00 | |
| 25_H | 69_H | 1.578 | 1.00 | |
| 129_L | 139_Y | 1.558 | 0.99 | |
| 62_W | 140_Q | 1.552 | 0.99 | |
| 147_V | 162_M | 1.54 | 0.99 | |
| 75_S | 78_D | 1.502 | 0.99 | |
| 76_N | 119_P | 1.498 | 0.99 | |
| 23_A | 27_A | 1.492 | 0.99 | |
| 64_N | 67_C | 1.488 | 0.99 | |
| 149_H | 153_A | 1.431 | 0.99 | |
| 50_R | 60_G | 1.374 | 0.98 | |
| 88_L | 139_Y | 1.341 | 0.98 | |
| 18_T | 72_L | 1.334 | 0.98 | |
| 60_G | 137_M | 1.332 | 0.98 | |
| 63_T | 67_C | 1.29 | 0.97 | |
| 88_L | 136_V | 1.28 | 0.97 | |
| 37_S | 84_C | 1.266 | 0.97 | |
| 5_H | 18_T | 1.263 | 0.97 | |
| 79_A | 82_R | 1.226 | 0.96 | |
| 47_L | 141_W | 1.224 | 0.96 | |
| 44_G | 124_R | 1.223 | 0.96 | |
| 74_E | 82_R | 1.207 | 0.95 | |
| 90_V | 125_T | 1.205 | 0.95 | |
| 146_D | 149_H | 1.2 | 0.95 | |
| 20_E | 23_A | 1.175 | 0.94 | |
| 61_V | 159_S | 1.172 | 0.94 | |
| 103_R | 117_V | 1.172 | 0.94 | |
| 131_I | 139_Y | 1.16 | 0.94 | |
| 45_Q | 143_D | 1.149 | 0.94 | |
| 36_S | 63_T | 1.138 | 0.93 | |
| 95_P | 123_A | 1.12 | 0.92 | |
| 39_L | 90_V | 1.094 | 0.91 | |
| 45_Q | 146_D | 1.094 | 0.91 | |
| 25_H | 32_H | 1.084 | 0.91 | |
| 34_A | 104_Y | 1.076 | 0.90 | |
| 143_D | 147_V | 1.067 | 0.90 | |
| 36_S | 67_C | 1.064 | 0.90 | |
| 105_R | 115_N | 1.048 | 0.89 | |
| 36_S | 64_N | 1.044 | 0.88 | |
| 44_G | 73_G | 1.038 | 0.88 | |
| 131_I | 136_V | 1.028 | 0.87 | |
| 35_F | 79_A | 1.016 | 0.86 | |
| 140_Q | 150_G | 1.014 | 0.86 | |
| 21_K | 83_R | 1.012 | 0.86 | |
| 21_K | 67_C | 1.01 | 0.86 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2dhoA | 1 | 0.989 | 100 | 0.343 | Contact Map | 0.87 |
| 2pnyA | 1 | 0.9945 | 100 | 0.346 | Contact Map | 0.883 |
| 1hztA | 1 | 1 | 100 | 0.409 | Contact Map | 0.801 |
| 3dupA | 2 | 0.978 | 100 | 0.46 | Contact Map | 0.656 |
| 1q27A | 1 | 0.9231 | 100 | 0.517 | Contact Map | 0.37 |
| 2fkbA | 3 | 0.9396 | 99.9 | 0.526 | Contact Map | 0.73 |
| 2xsqA | 1 | 0.9396 | 99.9 | 0.613 | Contact Map | 0.411 |
| 3e57A | 2 | 0.9066 | 99.8 | 0.649 | Contact Map | 0.485 |
| 1sjyA | 1 | 0.8462 | 99.8 | 0.655 | Contact Map | 0.649 |
| 1u20A | 2 | 0.9505 | 99.8 | 0.658 | Contact Map | 0.29 |
Sequence Conservation (Image Generated using WebLogo v3)