| UniProt: | Q46810 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13060 | ||
| Length: | 192 (188) | ||
| Sequences: | 3991 | ||
| Seq/Len: | 21.23 |
| MOCA
Paralog alert: 0.71 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: MOBA MOCA |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 29_G | 37_K | 4.965 | 1.00 | |
| 17_M | 24_L | 2.644 | 1.00 | |
| 45_R | 68_T | 2.629 | 1.00 | |
| 22_M | 100_G | 2.524 | 1.00 | |
| 6_C | 39_A | 2.303 | 1.00 | |
| 30_T | 33_D | 2.28 | 1.00 | |
| 6_C | 43_C | 2.257 | 1.00 | |
| 109_I | 172_I | 2.059 | 1.00 | |
| 5_D | 92_T | 2.02 | 1.00 | |
| 7_I | 86_A | 1.999 | 1.00 | |
| 104_T | 185_A | 1.913 | 1.00 | |
| 106_T | 172_I | 1.892 | 1.00 | |
| 95_C | 138_K | 1.89 | 1.00 | |
| 39_A | 98_T | 1.881 | 1.00 | |
| 117_R | 122_I | 1.875 | 1.00 | |
| 24_L | 182_F | 1.856 | 1.00 | |
| 7_I | 95_C | 1.833 | 1.00 | |
| 47_I | 70_I | 1.817 | 1.00 | |
| 77_Q | 81_T | 1.757 | 1.00 | |
| 143_Q | 159_M | 1.737 | 1.00 | |
| 29_G | 34_T | 1.727 | 1.00 | |
| 99_H | 102_M | 1.692 | 1.00 | |
| 96_F | 110_F | 1.653 | 1.00 | |
| 53_R | 56_E | 1.636 | 1.00 | |
| 5_D | 45_R | 1.631 | 1.00 | |
| 178_T | 181_D | 1.611 | 1.00 | |
| 94_H | 137_S | 1.589 | 1.00 | |
| 119_D | 163_Y | 1.587 | 1.00 | |
| 29_G | 33_D | 1.579 | 1.00 | |
| 106_T | 109_I | 1.555 | 1.00 | |
| 98_T | 110_F | 1.538 | 1.00 | |
| 41_Q | 107_I | 1.521 | 1.00 | |
| 121_A | 160_G | 1.51 | 1.00 | |
| 98_T | 105_L | 1.508 | 1.00 | |
| 107_I | 111_R | 1.498 | 1.00 | |
| 33_D | 37_K | 1.493 | 1.00 | |
| 83_V | 97_L | 1.486 | 1.00 | |
| 72_N | 81_T | 1.485 | 1.00 | |
| 176_I | 185_A | 1.477 | 1.00 | |
| 152_N | 155_Q | 1.458 | 1.00 | |
| 50_T | 69_I | 1.438 | 1.00 | |
| 48_L | 67_I | 1.433 | 1.00 | |
| 36_I | 46_I | 1.427 | 1.00 | |
| 58_H | 71_H | 1.399 | 0.99 | |
| 26_W | 31_I | 1.389 | 0.99 | |
| 8_I | 36_I | 1.383 | 0.99 | |
| 5_D | 90_V | 1.357 | 0.99 | |
| 88_P | 145_I | 1.346 | 0.99 | |
| 138_K | 141_L | 1.335 | 0.99 | |
| 12_G | 16_R | 1.328 | 0.99 | |
| 56_E | 59_E | 1.316 | 0.99 | |
| 8_I | 39_A | 1.298 | 0.99 | |
| 54_G | 58_H | 1.276 | 0.99 | |
| 40_L | 66_N | 1.273 | 0.99 | |
| 49_V | 86_A | 1.269 | 0.99 | |
| 181_D | 184_T | 1.269 | 0.99 | |
| 87_V | 145_I | 1.263 | 0.99 | |
| 38_N | 41_Q | 1.26 | 0.99 | |
| 143_Q | 160_G | 1.236 | 0.98 | |
| 19_Q | 25_P | 1.235 | 0.98 | |
| 97_L | 136_V | 1.229 | 0.98 | |
| 50_T | 58_H | 1.225 | 0.98 | |
| 13_L | 76_A | 1.223 | 0.98 | |
| 30_T | 34_T | 1.211 | 0.98 | |
| 40_L | 46_I | 1.208 | 0.98 | |
| 90_V | 95_C | 1.206 | 0.98 | |
| 83_V | 153_M | 1.206 | 0.98 | |
| 54_G | 71_H | 1.196 | 0.98 | |
| 123_L | 130_P | 1.193 | 0.98 | |
| 143_Q | 156_A | 1.174 | 0.98 | |
| 113_I | 122_I | 1.13 | 0.97 | |
| 38_N | 107_I | 1.123 | 0.97 | |
| 174_L | 185_A | 1.112 | 0.96 | |
| 121_A | 157_L | 1.101 | 0.96 | |
| 51_G | 76_A | 1.096 | 0.96 | |
| 156_A | 160_G | 1.094 | 0.96 | |
| 81_T | 84_K | 1.078 | 0.95 | |
| 79_L | 82_S | 1.075 | 0.95 | |
| 4_I | 114_W | 1.068 | 0.95 | |
| 94_H | 135_L | 1.066 | 0.95 | |
| 94_H | 117_R | 1.065 | 0.95 | |
| 17_M | 179_P | 1.061 | 0.95 | |
| 8_I | 35_S | 1.061 | 0.95 | |
| 10_A | 48_L | 1.061 | 0.95 | |
| 20_W | 53_R | 1.059 | 0.95 | |
| 117_R | 135_L | 1.055 | 0.95 | |
| 144_A | 147_R | 1.052 | 0.95 | |
| 125_L | 166_E | 1.049 | 0.94 | |
| 30_T | 60_R | 1.048 | 0.94 | |
| 167_I | 173_I | 1.048 | 0.94 | |
| 136_V | 144_A | 1.047 | 0.94 | |
| 81_T | 85_A | 1.039 | 0.94 | |
| 50_T | 54_G | 1.035 | 0.94 | |
| 27_E | 34_T | 1.032 | 0.94 | |
| 24_L | 179_P | 1.031 | 0.94 | |
| 180_D | 183_I | 1.03 | 0.94 | |
| 33_D | 60_R | 1.028 | 0.94 | |
| 93_E | 138_K | 1.028 | 0.94 | |
| 72_N | 82_S | 1.021 | 0.93 | |
| 96_F | 114_W | 1.017 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2weeA | 2 | 0.9844 | 100 | 0.22 | Contact Map | 0.757 |
| 2wawA | 1 | 0.9896 | 100 | 0.223 | Contact Map | 0.666 |
| 1e5kA | 1 | 0.9688 | 100 | 0.243 | Contact Map | 0.722 |
| 3d5nA | 8 | 0.9635 | 100 | 0.28 | Contact Map | 0.715 |
| 2e8bA | 1 | 0.9583 | 100 | 0.296 | Contact Map | 0.616 |
| 3ngwA | 1 | 0.9427 | 100 | 0.312 | Contact Map | 0.662 |
| 2px7A | 2 | 0.9531 | 99.9 | 0.427 | Contact Map | 0.74 |
| 1i52A | 1 | 0.9844 | 99.9 | 0.438 | Contact Map | 0.756 |
| 1vgwA | 6 | 0.9844 | 99.9 | 0.439 | Contact Map | 0.707 |
| 1vpaA | 2 | 0.974 | 99.9 | 0.444 | Contact Map | 0.729 |
Sequence Conservation (Image Generated using WebLogo v3)