| UniProt: | P77626 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13757 | ||
| Length: | 178 (173) | ||
| Sequences: | 2528 | ||
| Seq/Len: | 14.61 |
| YDCN
Paralog alert: 0.63 [within 20: 0.03] - ratio of genomes with paralogs Cluster includes: PUUR YDCN |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 129_D | 168_H | 4.344 | 1.00 | |
| 131_Q | 144_N | 3.844 | 1.00 | |
| 133_D | 160_R | 3.008 | 1.00 | |
| 132_L | 167_V | 2.992 | 1.00 | |
| 133_D | 140_W | 2.966 | 1.00 | |
| 131_Q | 142_T | 2.548 | 1.00 | |
| 103_S | 168_H | 2.524 | 1.00 | |
| 133_D | 142_T | 2.487 | 1.00 | |
| 129_D | 145_C | 2.447 | 1.00 | |
| 133_D | 162_G | 2.423 | 1.00 | |
| 24_S | 28_E | 2.287 | 1.00 | |
| 23_L | 37_L | 2.278 | 1.00 | |
| 134_L | 149_V | 2.149 | 1.00 | |
| 25_R | 29_A | 2.134 | 1.00 | |
| 15_L | 61_V | 2.064 | 1.00 | |
| 14_Q | 18_Q | 2.035 | 1.00 | |
| 143_L | 147_E | 2.028 | 1.00 | |
| 101_H | 124_H | 1.887 | 1.00 | |
| 107_A | 166_T | 1.879 | 1.00 | |
| 137_D | 155_V | 1.841 | 1.00 | |
| 24_S | 34_K | 1.781 | 1.00 | |
| 105_Q | 166_T | 1.771 | 1.00 | |
| 21_W | 29_A | 1.762 | 1.00 | |
| 105_Q | 168_H | 1.73 | 1.00 | |
| 128_I | 170_H | 1.72 | 1.00 | |
| 33_S | 36_M | 1.716 | 1.00 | |
| 123_E | 157_H | 1.684 | 1.00 | |
| 36_M | 40_I | 1.674 | 1.00 | |
| 25_R | 28_E | 1.602 | 1.00 | |
| 32_V | 51_T | 1.594 | 1.00 | |
| 135_C | 160_R | 1.584 | 1.00 | |
| 101_H | 172_L | 1.571 | 1.00 | |
| 32_V | 36_M | 1.498 | 1.00 | |
| 129_D | 166_T | 1.446 | 1.00 | |
| 40_I | 47_P | 1.431 | 1.00 | |
| 132_L | 169_F | 1.414 | 1.00 | |
| 99_F | 150_R | 1.398 | 0.99 | |
| 26_L | 59_L | 1.383 | 0.99 | |
| 26_L | 58_G | 1.382 | 0.99 | |
| 38_G | 42_R | 1.381 | 0.99 | |
| 135_C | 138_G | 1.368 | 0.99 | |
| 125_V | 149_V | 1.367 | 0.99 | |
| 136_V | 155_V | 1.356 | 0.99 | |
| 127_V | 167_V | 1.34 | 0.99 | |
| 135_C | 140_W | 1.324 | 0.99 | |
| 111_I | 160_R | 1.295 | 0.99 | |
| 21_W | 26_L | 1.292 | 0.99 | |
| 76_S | 79_D | 1.26 | 0.99 | |
| 35_A | 38_G | 1.254 | 0.99 | |
| 108_S | 161_N | 1.253 | 0.99 | |
| 36_M | 51_T | 1.25 | 0.99 | |
| 124_H | 148_G | 1.245 | 0.98 | |
| 56_A | 61_V | 1.225 | 0.98 | |
| 62_P | 65_T | 1.211 | 0.98 | |
| 16_R | 41_E | 1.21 | 0.98 | |
| 88_T | 103_S | 1.209 | 0.98 | |
| 108_S | 165_Q | 1.198 | 0.98 | |
| 151_F | 157_H | 1.196 | 0.98 | |
| 125_V | 171_S | 1.19 | 0.98 | |
| 36_M | 39_Q | 1.185 | 0.98 | |
| 87_I | 91_F | 1.185 | 0.98 | |
| 129_D | 165_Q | 1.179 | 0.98 | |
| 127_V | 169_F | 1.176 | 0.98 | |
| 131_Q | 163_G | 1.173 | 0.98 | |
| 106_M | 169_F | 1.169 | 0.97 | |
| 13_K | 17_Q | 1.156 | 0.97 | |
| 135_C | 158_I | 1.13 | 0.97 | |
| 111_I | 158_I | 1.121 | 0.97 | |
| 7_F | 43_N | 1.12 | 0.96 | |
| 126_V | 170_H | 1.114 | 0.96 | |
| 21_W | 25_R | 1.096 | 0.96 | |
| 9_S | 43_N | 1.084 | 0.96 | |
| 103_S | 126_V | 1.068 | 0.95 | |
| 30_T | 58_G | 1.066 | 0.95 | |
| 15_L | 19_R | 1.065 | 0.95 | |
| 122_I | 150_R | 1.065 | 0.95 | |
| 23_L | 38_G | 1.063 | 0.95 | |
| 12_L | 55_I | 1.058 | 0.95 | |
| 11_T | 14_Q | 1.054 | 0.95 | |
| 88_T | 105_Q | 1.054 | 0.95 | |
| 37_L | 55_I | 1.05 | 0.94 | |
| 142_T | 162_G | 1.044 | 0.94 | |
| 144_N | 147_E | 1.029 | 0.94 | |
| 56_A | 66_F | 1.025 | 0.93 | |
| 106_M | 110_A | 1.019 | 0.93 | |
| 163_G | 167_V | 1.004 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1y9qA | 1 | 0.9944 | 100 | 0.323 | Contact Map | 0.729 |
| 2bnmA | 2 | 0.9775 | 100 | 0.371 | Contact Map | 0.711 |
| 3g7dA | 1 | 0.9831 | 100 | 0.378 | Contact Map | 0.631 |
| 2p5tA | 4 | 0.882 | 99.9 | 0.477 | Contact Map | 0.072 |
| 1j58A | 1 | 0.8596 | 99.9 | 0.527 | Contact Map | 0.54 |
| 4b29A | 1 | 0.9775 | 99.8 | 0.585 | Contact Map | 0.573 |
| 3bu7A | 2 | 0.9775 | 99.7 | 0.626 | Contact Map | 0.488 |
| 3ivpA | 4 | 0.6798 | 99.7 | 0.632 | Contact Map | 0.712 |
| 1rc6A | 2 | 0.7079 | 99.7 | 0.648 | Contact Map | 0.668 |
| 3eqeA | 2 | 0.809 | 99.6 | 0.656 | Contact Map | 0.797 |
Sequence Conservation (Image Generated using WebLogo v3)