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OPENSEQ.org
YDAV - Uncharacterized protein YdaV
UniProt: P77546 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13364
Length: 248 (233)
Sequences: 915
Seq/Len: 3.93
YDAV
Paralog alert: 0.40 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: DNAC YDAV
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
220_D 236_S 5.078 1.00
137_V 169_L 3.187 1.00
118_A 202_L 3.167 1.00
122_G 132_V 3.129 1.00
122_G 168_V 2.938 1.00
201_M 222_M 2.459 1.00
73_F 120_A 2.219 1.00
118_A 168_V 2.07 1.00
54_R 58_I 2.056 1.00
132_V 168_V 2.038 1.00
64_I 122_G 1.974 1.00
192_R 199_V 1.973 1.00
90_A 121_I 1.934 1.00
174_I 217_R 1.815 1.00
167_L 188_I 1.795 0.99
86_A 230_V 1.77 0.99
76_Y 116_H 1.753 0.99
130_Q 165_D 1.719 0.99
52_Q 56_E 1.637 0.99
92_S 96_E 1.621 0.99
116_H 120_A 1.608 0.99
27_T 30_E 1.563 0.98
94_A 125_L 1.562 0.98
105_A 203_T 1.546 0.98
134_V 202_L 1.538 0.98
171_E 202_L 1.538 0.98
171_E 175_Q 1.528 0.98
81_E 85_Y 1.523 0.98
112_T 232_F 1.523 0.98
93_I 198_S 1.522 0.98
71_C 116_H 1.511 0.98
144_L 154_G 1.482 0.97
93_I 97_L 1.482 0.97
76_Y 117_L 1.454 0.97
123_N 127_K 1.441 0.97
94_A 124_R 1.438 0.97
52_Q 55_V 1.417 0.96
46_I 50_N 1.4 0.96
36_L 39_G 1.389 0.96
206_N 209_A 1.382 0.95
89_Q 228_R 1.367 0.95
159_R 163_E 1.359 0.95
141_M 181_E 1.358 0.95
235_E 240_N 1.333 0.94
58_I 129_G 1.308 0.93
172_I 203_T 1.293 0.93
97_L 171_E 1.277 0.92
173_G 204_N 1.275 0.92
75_N 116_H 1.252 0.91
118_A 200_G 1.251 0.91
12_R 15_R 1.241 0.91
164_V 167_L 1.235 0.90
209_A 212_T 1.224 0.90
116_H 237_W 1.223 0.90
71_C 115_N 1.211 0.89
58_I 131_T 1.21 0.89
11_E 14_R 1.209 0.89
91_K 95_D 1.197 0.88
29_A 44_E 1.195 0.88
9_V 13_I 1.179 0.87
140_V 161_L 1.175 0.87
124_R 127_K 1.171 0.87
143_A 163_E 1.159 0.86
14_R 19_S 1.159 0.86
104_F 152_Q 1.147 0.85
133_I 164_V 1.145 0.85
107_S 229_W 1.129 0.84
103_N 198_S 1.127 0.84
142_S 187_Q 1.126 0.84
234_W 238_R 1.118 0.83
131_T 165_D 1.116 0.83
169_L 185_L 1.11 0.83
49_Q 53_L 1.106 0.82
107_S 203_T 1.105 0.82
172_I 201_M 1.105 0.82
85_Y 159_R 1.103 0.82
132_V 165_D 1.09 0.81
203_T 218_I 1.09 0.81
35_Q 38_E 1.088 0.81
73_F 94_A 1.069 0.79
147_S 154_G 1.068 0.79
68_H 119_A 1.049 0.78
102_T 228_R 1.039 0.77
71_C 119_A 1.038 0.76
117_L 141_M 1.037 0.76
51_R 55_V 1.032 0.76
190_D 194_A 1.032 0.76
106_F 232_F 1.028 0.75
204_N 238_R 1.023 0.75
185_L 189_V 1.021 0.75
175_Q 181_E 1.013 0.74
93_I 103_N 1.011 0.74
171_E 220_D 1.009 0.74
9_V 17_A 1.009 0.74
136_T 186_H 1.008 0.73
119_A 125_L 1.001 0.73
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2qgzA10.98391000.439Contact Map0.597
4m4wJ60.98391000.447Contact Map0.674
2w58A20.7541000.525Contact Map0.682
3ec2A10.67341000.551Contact Map0.65
2vhjA30.943599.90.631Contact Map0.27
1l8qA10.721899.90.652Contact Map0.709
2z4sA10.963799.90.666Contact Map0.69
3bosA20.741999.80.676Contact Map0.67
1g5tA10.657399.70.729Contact Map0.563
2bjvA10.689599.60.732Contact Map0.419
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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