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SUFE - Cysteine desulfuration protein SufE
UniProt: P76194 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13961
Length: 138 (133)
Sequences: 918
Seq/Len: 6.90

SUFE
Paralog alert: 0.43 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: SUFE YGDK
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
95_Q 99_N 3.681 1.00
92_M 96_D 3.144 1.00
72_D 79_K 2.934 1.00
107_E 112_T 2.52 1.00
93_T 96_D 2.209 1.00
71_G 82_I 2.056 1.00
68_E 90_D 1.94 1.00
39_D 42_R 1.905 1.00
27_I 84_V 1.85 1.00
11_L 108_K 1.809 1.00
10_L 87_I 1.782 1.00
78_V 125_A 1.753 1.00
28_I 31_G 1.749 1.00
53_S 75_A 1.663 1.00
68_E 91_Q 1.635 1.00
37_L 42_R 1.593 1.00
43_S 46_N 1.589 1.00
15_L 108_K 1.585 1.00
47_S 54_Q 1.532 0.99
52_Q 118_S 1.523 0.99
42_R 72_D 1.52 0.99
129_A 133_K 1.517 0.99
41_D 70_Q 1.493 0.99
26_Y 29_E 1.471 0.99
77_I 114_H 1.46 0.99
89_Y 102_V 1.443 0.99
20_W 114_H 1.438 0.99
69_L 97_I 1.417 0.99
7_K 48_I 1.377 0.99
13_N 87_I 1.353 0.98
78_V 81_L 1.345 0.98
88_L 105_W 1.305 0.98
6_D 92_M 1.304 0.98
50_G 73_S 1.3 0.98
38_R 41_D 1.299 0.98
98_V 135_A 1.288 0.97
13_N 26_Y 1.275 0.97
128_R 132_A 1.244 0.97
25_L 76_A 1.237 0.97
37_L 70_Q 1.178 0.95
53_S 74_D 1.16 0.94
60_R 70_Q 1.159 0.94
62_N 68_E 1.154 0.94
22_E 25_L 1.152 0.94
26_Y 30_L 1.145 0.94
25_L 29_E 1.119 0.93
100_F 105_W 1.108 0.93
20_W 24_Y 1.103 0.92
30_L 87_I 1.103 0.92
94_P 98_V 1.101 0.92
89_Y 130_I 1.094 0.92
60_R 64_Q 1.082 0.91
25_L 52_Q 1.074 0.91
61_Q 94_P 1.041 0.89
71_G 78_V 1.02 0.88
55_V 83_A 1.002 0.86
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3g0mA111000.024Contact Map0.609
4lw4C20.99281000.037Contact Map0.591
1ni7A111000.041Contact Map0.454
1wloA10.95651000.108Contact Map0.301
4eb5C20.804339.30.927Contact Map0.373
3lvlA10.818834.20.929Contact Map0.387
2z7eA30.833325.10.934Contact Map0.51
2qq4A100.840621.80.936Contact Map0.479
1xjsA10.86968.40.947Contact Map0.341
1su0B10.87687.30.948Contact Map0.306

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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