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YGDK - Uncharacterized SufE-like protein YgdK
UniProt: P0AGF2 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13083
Length: 147 (136)
Sequences: 923
Seq/Len: 6.79

YGDK
Paralog alert: 0.43 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: SUFE YGDK
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
105_A 109_A 3.441 1.00
102_K 106_E 3.12 1.00
82_D 89_R 2.921 1.00
117_D 122_R 2.456 1.00
103_T 106_E 2.353 1.00
111_S 114_A 1.991 1.00
81_G 92_L 1.948 1.00
78_H 100_E 1.862 1.00
37_L 94_V 1.845 1.00
49_D 52_K 1.789 1.00
38_I 41_G 1.768 1.00
21_R 118_E 1.74 1.00
20_L 97_T 1.732 1.00
51_L 80_F 1.731 1.00
63_N 85_G 1.72 1.00
25_A 118_E 1.611 1.00
36_Q 39_M 1.598 1.00
47_L 52_K 1.574 1.00
53_A 56_K 1.569 1.00
139_A 143_A 1.54 0.99
52_K 82_D 1.515 0.99
78_H 101_G 1.486 0.99
62_E 128_S 1.47 0.99
88_V 135_A 1.451 0.99
57_E 64_R 1.427 0.99
99_V 112_P 1.413 0.99
30_W 124_Q 1.413 0.99
79_F 107_L 1.41 0.99
87_I 124_Q 1.406 0.99
48_P 51_L 1.341 0.98
23_T 36_Q 1.336 0.98
88_V 91_L 1.319 0.98
98_A 115_L 1.312 0.98
60_G 83_S 1.292 0.97
17_A 58_I 1.289 0.97
23_T 97_T 1.276 0.97
108_Q 145_K 1.254 0.97
138_E 142_A 1.176 0.95
47_L 80_F 1.172 0.95
35_R 86_R 1.171 0.95
63_N 84_E 1.169 0.95
36_Q 40_L 1.152 0.94
99_V 140_I 1.139 0.94
110_Q 115_L 1.131 0.93
11_F 15_V 1.127 0.93
40_L 97_T 1.123 0.93
70_T 80_F 1.095 0.92
35_R 39_M 1.089 0.91
30_W 34_Y 1.084 0.91
35_R 62_E 1.078 0.91
32_D 35_R 1.078 0.91
65_V 93_A 1.078 0.91
104_A 108_Q 1.073 0.91
69_Y 79_F 1.065 0.90
20_L 94_V 1.063 0.90
102_K 110_Q 1.039 0.89
34_Y 87_I 1.037 0.89
54_Q 59_A 1.024 0.88
76_K 103_T 1.022 0.88
12_G 15_V 1.021 0.88
62_E 86_R 1.017 0.87
69_Y 77_M 1.01 0.87
70_T 74_N 1 0.86
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4lw4C211000.036Contact Map0.645
1ni7A111000.038Contact Map0.489
3g0mA10.95241000.08Contact Map0.658
1wloA10.89121000.144Contact Map0.279
4eb5C20.748358.70.922Contact Map0.375
3lvlA10.761944.50.929Contact Map0.442
2z7eA30.802738.60.931Contact Map0.495
2qq4A100.789138.50.931Contact Map0.48
1su0B10.809512.30.946Contact Map0.341
1xjsA10.816311.70.946Contact Map0.367

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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