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OPENSEQ.org
PAAC - 1,2-phenylacetyl-CoA epoxidase, subunit C
UniProt: P76079 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13737
Length: 248 (247)
Sequences: 334
Seq/Len: 1.35
PAAC
Paralog alert: 0.03 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: PAAA PAAC
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
12_G 53_L 3.937 1.00
152_G 207_T 3.091 1.00
10_R 173_D 2.849 1.00
102_A 134_L 2.669 1.00
95_A 155_M 2.583 1.00
99_F 159_I 2.467 1.00
146_N 207_T 2.396 0.99
80_L 169_L 2.299 0.99
156_Q 209_N 2.27 0.99
14_N 221_K 2.269 0.99
156_Q 160_N 2.1 0.98
85_Q 165_F 2.095 0.98
64_D 67_T 2.078 0.98
34_I 136_F 2.074 0.98
50_R 65_E 2.002 0.98
236_M 239_L 1.854 0.96
166_T 195_W 1.829 0.95
53_L 68_L 1.811 0.95
179_L 185_A 1.792 0.94
52_F 119_L 1.776 0.94
3_Q 178_A 1.759 0.94
86_P 228_H 1.75 0.93
57_A 64_D 1.735 0.93
108_F 136_F 1.719 0.93
192_R 196_E 1.708 0.92
18_L 96_R 1.629 0.90
240_Q 243_L 1.622 0.90
71_T 240_Q 1.601 0.89
238_Y 242_V 1.578 0.88
94_I 141_L 1.575 0.88
106_A 198_E 1.535 0.86
52_F 108_F 1.521 0.85
20_Q 23_G 1.508 0.84
150_V 153_Q 1.497 0.84
138_R 202_G 1.456 0.81
141_L 202_G 1.436 0.80
19_S 100_I 1.434 0.80
89_N 154_K 1.414 0.79
4_L 8_T 1.401 0.78
101_D 136_F 1.394 0.77
19_S 46_L 1.372 0.76
98_Y 202_G 1.368 0.76
145_G 206_A 1.367 0.75
52_F 101_D 1.347 0.74
74_E 229_L 1.321 0.72
104_H 130_A 1.319 0.72
53_L 163_W 1.317 0.72
54_S 65_E 1.3 0.70
74_E 230_G 1.284 0.69
156_Q 207_T 1.284 0.69
95_A 158_A 1.281 0.68
98_Y 137_S 1.267 0.67
98_Y 141_L 1.265 0.67
29_A 90_F 1.264 0.67
41_I 136_F 1.255 0.66
52_F 136_F 1.254 0.66
58_E 118_Q 1.238 0.65
147_G 151_S 1.236 0.64
104_H 108_F 1.226 0.64
85_Q 226_T 1.217 0.63
176_D 179_L 1.205 0.62
106_A 191_L 1.2 0.61
101_D 104_H 1.199 0.61
17_V 232_M 1.182 0.59
221_K 232_M 1.18 0.59
5_T 60_A 1.177 0.59
150_V 154_K 1.156 0.57
152_G 156_Q 1.155 0.57
89_N 150_V 1.154 0.57
181_E 205_E 1.143 0.56
99_F 166_T 1.142 0.55
146_N 152_G 1.138 0.55
91_A 158_A 1.13 0.54
196_E 200_F 1.13 0.54
4_L 179_L 1.13 0.54
76_Q 165_F 1.119 0.53
113_E 181_E 1.117 0.53
141_L 155_M 1.116 0.53
196_E 210_V 1.113 0.53
64_D 159_I 1.11 0.52
70_F 236_M 1.106 0.52
105_V 127_I 1.099 0.51
101_D 137_S 1.098 0.51
81_L 219_G 1.088 0.50
174_E 210_V 1.087 0.50
89_N 92_D 1.086 0.50
41_I 101_D 1.085 0.50
203_I 207_T 1.083 0.50
160_N 209_N 1.081 0.49
104_H 136_F 1.08 0.49
42_G 46_L 1.076 0.49
67_T 245_G 1.076 0.49
98_Y 199_V 1.075 0.49
102_A 106_A 1.073 0.49
93_T 122_I 1.07 0.48
101_D 243_L 1.07 0.48
8_T 59_L 1.062 0.47
73_D 76_Q 1.054 0.47
99_F 162_L 1.052 0.46
35_D 39_A 1.052 0.46
16_L 69_A 1.051 0.46
145_G 207_T 1.05 0.46
58_E 63_G 1.046 0.46
90_F 144_L 1.037 0.45
239_L 246_Q 1.035 0.45
103_W 108_F 1.027 0.44
85_Q 228_H 1.022 0.43
55_Y 118_Q 1.021 0.43
244_P 248_W 1.018 0.43
146_N 206_A 1.017 0.43
39_A 102_A 1.008 0.42
134_L 198_E 1.002 0.41
73_D 242_V 1.001 0.41
81_L 97_Q 1 0.41
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1otkA211000.191Contact Map0.675
3pf7A20.98391000.368Contact Map0.414
3pvtA10.97981000.472Contact Map0.54
4mudA40.86691000.528Contact Map0.577
2incA10.971894.90.942Contact Map0.335
1mtyD20.971894.20.944Contact Map0.351
3ge3A10.963791.80.948Contact Map0.342
3u52A20.9677890.951Contact Map0.412
3ez0A40.794461.60.962Contact Map0.409
3u52C20.822654.30.964Contact Map0.416
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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