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OPENSEQ.org
DMSD - Tat proofreading chaperone DmsD
UniProt: P69853 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13847
Length: 204 (198)
Sequences: 622
Seq/Len: 3.14
DMSD
Paralog alert: 0.80 [within 20: 0.02] - ratio of genomes with paralogs
Cluster includes: DMSD TORD YCDY
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
110_M 134_M 3.145 1.00
107_R 125_E 2.988 1.00
21_F 182_A 2.891 1.00
71_A 172_H 2.871 1.00
93_D 100_G 2.674 1.00
128_F 159_S 2.538 1.00
162_F 166_F 2.092 1.00
106_L 110_M 2 1.00
167_I 183_R 1.972 1.00
27_S 31_A 1.957 1.00
73_Q 77_V 1.941 1.00
79_P 82_L 1.883 0.99
88_G 92_L 1.88 0.99
88_G 106_L 1.863 0.99
161_R 202_L 1.828 0.99
14_A 185_T 1.825 0.99
71_A 170_A 1.742 0.99
167_I 180_E 1.688 0.98
115_I 137_W 1.67 0.98
163_L 182_A 1.664 0.98
68_H 174_F 1.604 0.98
22_Y 129_G 1.564 0.97
170_A 173_P 1.538 0.97
136_A 140_E 1.499 0.96
159_S 163_L 1.477 0.96
106_L 131_L 1.463 0.95
91_W 165_V 1.455 0.95
135_A 147_C 1.429 0.94
17_L 182_A 1.404 0.94
18_G 133_L 1.399 0.94
159_S 186_L 1.382 0.93
21_F 128_F 1.381 0.93
86_P 124_P 1.377 0.93
15_R 140_E 1.37 0.93
21_F 178_L 1.355 0.92
166_F 179_G 1.348 0.92
179_G 182_A 1.337 0.91
164_D 177_A 1.324 0.91
16_V 20_L 1.319 0.91
77_V 82_L 1.309 0.90
191_S 194_L 1.292 0.89
131_L 134_M 1.292 0.89
135_A 185_T 1.277 0.89
71_A 74_R 1.272 0.88
131_L 150_L 1.271 0.88
47_P 129_G 1.256 0.88
14_A 147_C 1.252 0.87
197_V 201_P 1.237 0.87
15_R 136_A 1.216 0.85
93_D 102_S 1.206 0.85
161_R 186_L 1.199 0.84
16_V 150_L 1.194 0.84
103_T 125_E 1.172 0.82
20_L 174_F 1.165 0.82
200_K 203_F 1.147 0.80
88_G 131_L 1.135 0.79
135_A 189_W 1.131 0.79
163_L 179_G 1.12 0.78
14_A 135_A 1.115 0.78
22_Y 130_S 1.115 0.78
82_L 86_P 1.111 0.77
14_A 189_W 1.111 0.77
25_P 72_W 1.101 0.76
173_P 176_R 1.099 0.76
85_P 90_V 1.085 0.75
20_L 178_L 1.085 0.75
132_L 186_L 1.069 0.73
89_S 98_L 1.063 0.73
197_V 202_L 1.06 0.72
16_V 181_L 1.057 0.72
129_G 148_E 1.056 0.72
160_T 183_R 1.05 0.71
21_F 179_G 1.048 0.71
58_T 62_T 1.047 0.71
88_G 154_H 1.042 0.71
110_M 131_L 1.04 0.70
118_E 184_L 1.04 0.70
132_L 162_F 1.035 0.70
191_S 195_I 1.035 0.70
38_T 168_E 1.035 0.70
108_Q 138_L 1.034 0.70
72_W 76_F 1.032 0.70
191_S 196_P 1.027 0.69
170_A 176_R 1.027 0.69
77_V 127_H 1.026 0.69
59_A 177_A 1.022 0.68
106_L 134_M 1.017 0.68
149_E 153_W 1.01 0.67
138_L 142_G 1.004 0.66
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1s9uA111000.185Contact Map0.63
1n1cA20.98041000.271Contact Map0.578
2o9xA10.81861000.406Contact Map0.655
2xolA20.75491000.481Contact Map0.622
2c4mA40.30884.20.959Contact Map0.271
1g03A10.42164.10.959Contact Map0.437
1j2mA10.19613.10.962Contact Map0.597
2zqmA10.357830.962Contact Map0.319
1ytrA10.12252.70.963Contact Map0.571
4jrbA10.37252.60.963Contact Map0.6
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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