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OPENSEQ.org

TORD - Chaperone protein TorD
UniProt: P36662 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12195
Length: 199 (190)
Sequences: 635
Seq/Len: 3.34

TORD
Paralog alert: 0.80 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: DMSD TORD YCDY
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
20_F 188_L 3.103 1.00
108_L 132_L 3.061 1.00
77_D 178_F 2.847 1.00
105_K 123_A 2.782 1.00
126_L 165_L 2.287 1.00
168_F 172_C 2.237 1.00
104_I 108_L 2.071 1.00
173_R 189_L 1.972 1.00
26_D 30_T 1.963 1.00
169_V 188_L 1.934 1.00
79_C 83_L 1.933 1.00
165_L 192_V 1.869 0.99
94_A 98_K 1.864 0.99
94_A 104_I 1.811 0.99
13_Y 191_L 1.772 0.99
77_D 176_D 1.727 0.99
17_A 131_E 1.64 0.98
9_I 13_Y 1.619 0.98
20_F 126_L 1.619 0.98
57_L 183_A 1.616 0.98
85_T 88_Q 1.591 0.98
113_M 135_H 1.586 0.98
16_L 188_L 1.564 0.97
19_L 180_F 1.557 0.97
173_R 186_Q 1.542 0.97
176_D 179_G 1.521 0.97
74_L 180_F 1.492 0.96
185_S 188_L 1.488 0.96
9_I 191_L 1.483 0.96
53_A 190_V 1.481 0.96
13_Y 133_L 1.473 0.96
9_I 195_D 1.471 0.96
165_L 169_V 1.458 0.96
97_Y 171_R 1.436 0.95
21_S 127_A 1.426 0.95
94_A 129_Y 1.411 0.95
134_S 138_F 1.401 0.94
172_C 185_S 1.397 0.94
14_A 138_F 1.36 0.93
53_A 183_A 1.356 0.93
91_L 96_A 1.348 0.93
92_P 122_P 1.31 0.91
104_I 129_Y 1.291 0.90
93_Y 128_I 1.277 0.90
83_L 88_Q 1.238 0.88
9_I 133_L 1.226 0.87
9_I 156_K 1.219 0.87
128_I 168_F 1.208 0.86
111_A 155_Q 1.206 0.86
129_Y 132_L 1.201 0.86
24_L 78_F 1.195 0.85
97_Y 167_E 1.186 0.85
102_Q 109_V 1.184 0.84
17_A 93_Y 1.182 0.84
19_L 184_L 1.181 0.84
54_V 187_L 1.162 0.83
78_F 82_F 1.153 0.82
77_D 80_G 1.145 0.82
133_L 191_L 1.133 0.81
116_S 190_V 1.131 0.81
55_N 143_G 1.122 0.80
20_F 185_S 1.12 0.80
95_S 122_P 1.119 0.80
96_A 101_E 1.112 0.79
94_A 160_A 1.104 0.78
78_F 125_H 1.096 0.78
130_L 192_V 1.092 0.77
28_Q 187_L 1.091 0.77
68_D 179_G 1.089 0.77
51_T 55_N 1.088 0.77
105_K 164_W 1.079 0.76
169_V 185_S 1.077 0.76
166_P 173_R 1.067 0.75
13_Y 195_D 1.063 0.74
170_A 183_A 1.062 0.74
83_L 125_H 1.061 0.74
166_P 189_L 1.053 0.73
156_K 181_Y 1.049 0.73
16_L 180_F 1.045 0.73
14_A 134_S 1.041 0.72
106_R 110_E 1.04 0.72
20_F 184_L 1.032 0.71
23_E 83_L 1.029 0.71
179_G 182_A 1.029 0.71
69_D 112_G 1.028 0.71
24_L 185_S 1.028 0.71
94_A 132_L 1.027 0.71
40_W 66_V 1.026 0.71
68_D 72_L 1.024 0.70
88_Q 92_P 1.016 0.70
21_S 128_I 1.015 0.70
17_A 132_L 1.01 0.69
13_Y 131_E 1.008 0.69
133_L 158_L 1.007 0.69
102_Q 105_K 1.006 0.69
17_A 127_A 1.005 0.68
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1n1cA20.93971000.243Contact Map0.584
1s9uA10.88941000.303Contact Map0.642
2o9xA10.7991000.403Contact Map0.581
2xolA20.77391000.428Contact Map0.599
2zqmA10.37196.40.951Contact Map0.275
1g03A10.457330.958Contact Map0.424
3qatA20.51762.70.96Contact Map0.177
2aq4A10.30652.30.961Contact Map0.266
3c4rA40.47742.30.961Contact Map0.711
2jd3A20.3921.90.962Contact Map0.238

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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