| UniProt: | P69503 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10051 | ||
| Length: | 183 (174) | ||
| Sequences: | 3914 | ||
| Seq/Len: | 22.49 |
| APT
Paralog alert: 0.86 [within 20: 0.02] - ratio of genomes with paralogs Cluster includes: APT PYRE |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 121_K | 148_E | 4.186 | 1.00 | |
| 142_I | 147_G | 3.15 | 1.00 | |
| 59_K | 120_D | 3.009 | 1.00 | |
| 58_T | 120_D | 2.565 | 1.00 | |
| 162_G | 165_Q | 2.449 | 1.00 | |
| 164_E | 168_E | 2.338 | 1.00 | |
| 159_F | 179_P | 2.338 | 1.00 | |
| 46_D | 77_G | 2.228 | 1.00 | |
| 117_K | 120_D | 2.194 | 1.00 | |
| 94_E | 113_V | 2.136 | 1.00 | |
| 99_T | 108_Q | 2.089 | 1.00 | |
| 52_Y | 123_L | 2.046 | 1.00 | |
| 157_N | 164_E | 2.033 | 1.00 | |
| 71_G | 82_F | 1.968 | 1.00 | |
| 98_E | 140_K | 1.952 | 1.00 | |
| 98_E | 144_R | 1.931 | 1.00 | |
| 50_E | 53_K | 1.907 | 1.00 | |
| 42_A | 77_G | 1.894 | 1.00 | |
| 121_K | 150_A | 1.845 | 1.00 | |
| 136_E | 140_K | 1.837 | 1.00 | |
| 101_D | 106_T | 1.819 | 1.00 | |
| 51_R | 175_Y | 1.813 | 1.00 | |
| 56_G | 121_K | 1.753 | 1.00 | |
| 47_L | 50_E | 1.717 | 1.00 | |
| 17_S | 27_L | 1.65 | 1.00 | |
| 61_V | 85_V | 1.648 | 1.00 | |
| 136_E | 166_R | 1.646 | 1.00 | |
| 135_I | 152_A | 1.64 | 1.00 | |
| 152_A | 172_I | 1.638 | 1.00 | |
| 139_V | 172_I | 1.626 | 1.00 | |
| 135_I | 154_F | 1.612 | 1.00 | |
| 143_R | 172_I | 1.606 | 1.00 | |
| 97_S | 108_Q | 1.556 | 1.00 | |
| 85_V | 138_T | 1.531 | 1.00 | |
| 16_K | 93_R | 1.526 | 1.00 | |
| 165_Q | 168_E | 1.521 | 1.00 | |
| 118_P | 146_G | 1.52 | 1.00 | |
| 20_D | 24_P | 1.499 | 1.00 | |
| 49_V | 77_G | 1.499 | 1.00 | |
| 154_F | 176_S | 1.495 | 1.00 | |
| 55_A | 173_T | 1.495 | 1.00 | |
| 42_A | 76_L | 1.471 | 1.00 | |
| 165_Q | 169_K | 1.465 | 1.00 | |
| 57_I | 80_V | 1.462 | 1.00 | |
| 140_K | 143_R | 1.454 | 1.00 | |
| 42_A | 79_G | 1.441 | 1.00 | |
| 61_V | 142_I | 1.432 | 1.00 | |
| 52_Y | 153_A | 1.428 | 1.00 | |
| 63_T | 138_T | 1.423 | 1.00 | |
| 48_L | 74_V | 1.406 | 0.99 | |
| 75_A | 82_F | 1.399 | 0.99 | |
| 49_V | 78_L | 1.394 | 0.99 | |
| 49_V | 74_V | 1.392 | 0.99 | |
| 9_E | 13_N | 1.381 | 0.99 | |
| 39_K | 79_G | 1.369 | 0.99 | |
| 140_K | 144_R | 1.365 | 0.99 | |
| 59_K | 83_V | 1.357 | 0.99 | |
| 10_Y | 43_L | 1.335 | 0.99 | |
| 139_V | 152_A | 1.332 | 0.99 | |
| 99_T | 106_T | 1.309 | 0.99 | |
| 9_E | 12_K | 1.305 | 0.99 | |
| 48_L | 153_A | 1.299 | 0.99 | |
| 14_S | 37_D | 1.291 | 0.99 | |
| 157_N | 179_P | 1.286 | 0.99 | |
| 143_R | 148_E | 1.282 | 0.99 | |
| 17_S | 29_R | 1.266 | 0.99 | |
| 140_K | 170_Q | 1.252 | 0.99 | |
| 129_L | 154_F | 1.246 | 0.98 | |
| 154_F | 174_S | 1.244 | 0.98 | |
| 123_L | 151_D | 1.211 | 0.98 | |
| 14_S | 40_A | 1.186 | 0.98 | |
| 139_V | 143_R | 1.18 | 0.98 | |
| 73_P | 76_L | 1.168 | 0.97 | |
| 151_D | 173_T | 1.147 | 0.97 | |
| 143_R | 170_Q | 1.145 | 0.97 | |
| 32_T | 112_H | 1.138 | 0.97 | |
| 156_I | 180_F | 1.135 | 0.97 | |
| 96_I | 145_L | 1.125 | 0.97 | |
| 41_Y | 72_A | 1.124 | 0.97 | |
| 151_D | 175_Y | 1.123 | 0.97 | |
| 58_T | 119_G | 1.119 | 0.96 | |
| 61_V | 138_T | 1.116 | 0.96 | |
| 34_L | 44_S | 1.106 | 0.96 | |
| 176_S | 179_P | 1.085 | 0.96 | |
| 43_L | 46_D | 1.085 | 0.96 | |
| 19_Q | 27_L | 1.071 | 0.95 | |
| 47_L | 177_L | 1.067 | 0.95 | |
| 116_I | 147_G | 1.057 | 0.95 | |
| 52_Y | 57_I | 1.056 | 0.95 | |
| 93_R | 112_H | 1.041 | 0.94 | |
| 124_V | 138_T | 1.04 | 0.94 | |
| 56_G | 80_V | 1.039 | 0.94 | |
| 128_L | 156_I | 1.038 | 0.94 | |
| 97_S | 110_E | 1.033 | 0.94 | |
| 149_V | 172_I | 1.028 | 0.94 | |
| 119_G | 148_E | 1.019 | 0.93 | |
| 49_V | 53_K | 1.005 | 0.93 | |
| 166_R | 169_K | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 4m0kA | 4 | 0.9672 | 100 | 0.267 | Contact Map | 0.835 |
| 4lzaA | 2 | 0.9672 | 100 | 0.29 | Contact Map | 0.879 |
| 2dy0A | 2 | 1 | 100 | 0.329 | Contact Map | 0.852 |
| 1qb7A | 1 | 1 | 100 | 0.359 | Contact Map | 0.669 |
| 3qw4B | 2 | 0.9071 | 100 | 0.378 | Contact Map | 0.682 |
| 1zn8A | 2 | 0.9672 | 100 | 0.392 | Contact Map | 0.823 |
| 1g2qA | 2 | 0.9781 | 100 | 0.396 | Contact Map | 0.774 |
| 1l1qA | 1 | 0.9672 | 100 | 0.404 | Contact Map | 0.582 |
| 2wnsA | 2 | 0.8907 | 100 | 0.41 | Contact Map | 0.769 |
| 3mjdA | 4 | 0.9126 | 100 | 0.416 | Contact Map | 0.757 |
Sequence Conservation (Image Generated using WebLogo v3)