| UniProt: | P0A7E3 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10808 | ||
| Length: | 213 (213) | ||
| Sequences: | 1814 | ||
| Seq/Len: | 8.52 |
| PYRE
Paralog alert: 0.04 [within 20: 0.00] - ratio of genomes with paralogs Cluster includes: APT PYRE |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 119_R | 146_T | 3.694 | 1.00 | |
| 24_T | 30_K | 3.581 | 1.00 | |
| 140_I | 145_A | 3.528 | 1.00 | |
| 22_E | 30_K | 3.49 | 1.00 | |
| 157_Q | 185_K | 3.197 | 1.00 | |
| 57_L | 121_M | 2.665 | 1.00 | |
| 78_A | 95_Y | 2.231 | 1.00 | |
| 10_E | 14_S | 2.13 | 1.00 | |
| 152_I | 180_S | 2.124 | 1.00 | |
| 206_A | 209_E | 1.964 | 1.00 | |
| 138_E | 142_A | 1.952 | 1.00 | |
| 201_L | 205_K | 1.887 | 1.00 | |
| 25_L | 31_S | 1.86 | 1.00 | |
| 57_L | 151_L | 1.855 | 1.00 | |
| 149_G | 179_I | 1.835 | 1.00 | |
| 7_Q | 10_E | 1.834 | 1.00 | |
| 138_E | 174_Y | 1.799 | 1.00 | |
| 138_E | 141_Q | 1.775 | 1.00 | |
| 51_R | 84_A | 1.723 | 1.00 | |
| 137_M | 176_C | 1.691 | 1.00 | |
| 69_G | 78_A | 1.66 | 1.00 | |
| 98_N | 139_I | 1.653 | 1.00 | |
| 40_F | 49_L | 1.64 | 1.00 | |
| 141_Q | 176_C | 1.634 | 1.00 | |
| 19_K | 23_F | 1.605 | 1.00 | |
| 6_R | 193_E | 1.548 | 1.00 | |
| 168_Q | 173_D | 1.542 | 1.00 | |
| 133_I | 150_V | 1.522 | 1.00 | |
| 119_R | 148_A | 1.509 | 1.00 | |
| 80_T | 83_V | 1.508 | 1.00 | |
| 56_A | 179_I | 1.505 | 1.00 | |
| 50_G | 80_T | 1.47 | 1.00 | |
| 127_I | 160_G | 1.459 | 0.99 | |
| 110_N | 142_A | 1.449 | 0.99 | |
| 161_R | 172_R | 1.449 | 0.99 | |
| 48_L | 92_D | 1.449 | 0.99 | |
| 170_V | 178_V | 1.44 | 0.99 | |
| 141_Q | 146_T | 1.436 | 0.99 | |
| 7_Q | 45_D | 1.421 | 0.99 | |
| 192_E | 205_K | 1.407 | 0.99 | |
| 124_D | 127_I | 1.405 | 0.99 | |
| 52_F | 181_I | 1.404 | 0.99 | |
| 63_E | 119_R | 1.403 | 0.99 | |
| 52_F | 55_E | 1.395 | 0.99 | |
| 152_I | 178_V | 1.376 | 0.99 | |
| 127_I | 178_V | 1.37 | 0.99 | |
| 71_A | 75_I | 1.364 | 0.99 | |
| 49_L | 181_I | 1.359 | 0.99 | |
| 68_F | 96_C | 1.358 | 0.99 | |
| 10_E | 194_K | 1.35 | 0.99 | |
| 134_R | 174_Y | 1.34 | 0.99 | |
| 26_K | 131_T | 1.327 | 0.99 | |
| 101_E | 104_D | 1.325 | 0.99 | |
| 122_L | 133_I | 1.308 | 0.99 | |
| 65_D | 119_R | 1.306 | 0.99 | |
| 169_E | 173_D | 1.283 | 0.98 | |
| 48_L | 84_A | 1.283 | 0.98 | |
| 199_E | 202_A | 1.279 | 0.98 | |
| 127_I | 152_I | 1.253 | 0.98 | |
| 150_V | 176_C | 1.252 | 0.98 | |
| 149_G | 177_K | 1.25 | 0.98 | |
| 26_K | 104_D | 1.237 | 0.98 | |
| 157_Q | 183_T | 1.231 | 0.98 | |
| 202_A | 205_K | 1.23 | 0.98 | |
| 192_E | 199_E | 1.202 | 0.97 | |
| 131_T | 135_E | 1.201 | 0.97 | |
| 12_A | 35_F | 1.193 | 0.97 | |
| 54_A | 81_T | 1.192 | 0.97 | |
| 65_D | 118_G | 1.189 | 0.97 | |
| 110_N | 139_I | 1.187 | 0.97 | |
| 147_L | 176_C | 1.17 | 0.97 | |
| 22_E | 32_P | 1.154 | 0.96 | |
| 200_H | 203_A | 1.154 | 0.96 | |
| 37_A | 126_V | 1.146 | 0.96 | |
| 29_R | 158_E | 1.144 | 0.96 | |
| 164_I | 168_Q | 1.143 | 0.96 | |
| 199_E | 203_A | 1.127 | 0.95 | |
| 122_L | 147_L | 1.12 | 0.95 | |
| 66_L | 96_C | 1.115 | 0.95 | |
| 164_I | 167_I | 1.114 | 0.95 | |
| 155_D | 183_T | 1.099 | 0.95 | |
| 202_A | 206_A | 1.099 | 0.95 | |
| 122_L | 140_I | 1.077 | 0.94 | |
| 115_A | 145_A | 1.077 | 0.94 | |
| 27_S | 128_T | 1.075 | 0.94 | |
| 102_A | 110_N | 1.073 | 0.94 | |
| 5_Q | 183_T | 1.06 | 0.93 | |
| 124_D | 181_I | 1.053 | 0.93 | |
| 9_I | 182_I | 1.052 | 0.93 | |
| 11_F | 52_F | 1.051 | 0.93 | |
| 116_L | 140_I | 1.047 | 0.93 | |
| 54_A | 91_L | 1.037 | 0.92 | |
| 47_A | 83_V | 1.024 | 0.91 | |
| 79_T | 95_Y | 1.023 | 0.91 | |
| 53_Y | 151_L | 1.02 | 0.91 | |
| 132_A | 137_M | 1.019 | 0.91 | |
| 205_K | 209_E | 1.014 | 0.91 | |
| 55_E | 58_V | 1.013 | 0.91 | |
| 168_Q | 213_V | 1.006 | 0.90 | |
| 206_A | 210_E | 1.004 | 0.90 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3n2lA | 8 | 0.9953 | 100 | 0.253 | Contact Map | 0.733 |
| 3mjdA | 4 | 0.9859 | 100 | 0.278 | Contact Map | 0.737 |
| 1lh0A | 2 | 0.9953 | 100 | 0.283 | Contact Map | 0.724 |
| 3qw4B | 2 | 0.9108 | 100 | 0.302 | Contact Map | 0.637 |
| 2ps1A | 2 | 0.9812 | 100 | 0.324 | Contact Map | 0.725 |
| 2wnsA | 2 | 0.9296 | 100 | 0.352 | Contact Map | 0.785 |
| 3m3hA | 1 | 0.9437 | 100 | 0.354 | Contact Map | 0.748 |
| 4fymA | 8 | 0.9249 | 100 | 0.38 | Contact Map | 0.741 |
| 3dezA | 2 | 0.939 | 100 | 0.38 | Contact Map | 0.788 |
| 2aeeA | 2 | 0.9343 | 100 | 0.395 | Contact Map | 0.784 |
Sequence Conservation (Image Generated using WebLogo v3)