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OPENSEQ.org
YRAP - Uncharacterized protein YraP
UniProt: P64596 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12781
Length: 191 (186)
Sequences: 545
Seq/Len: 2.93
YRAP
Paralog alert: 0.56 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: OSMY YRAP
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
129_T 151_T 4.055 1.00
54_V 98_A 2.975 1.00
73_T 82_V 2.867 1.00
51_E 74_A 2.442 1.00
85_S 111_I 2.26 1.00
42_G 46_D 2.145 1.00
112_R 157_F 1.997 1.00
162_V 187_F 1.889 0.99
167_A 189_F 1.889 0.99
69_R 117_I 1.778 0.99
164_E 168_K 1.694 0.98
98_A 101_V 1.678 0.98
185_T 189_F 1.644 0.98
147_V 162_V 1.64 0.98
128_I 151_T 1.635 0.98
112_R 155_E 1.622 0.97
180_V 183_V 1.604 0.97
69_R 122_A 1.599 0.97
147_V 170_A 1.56 0.97
172_D 176_R 1.519 0.96
95_K 99_M 1.498 0.95
132_V 174_A 1.497 0.95
171_A 175_S 1.494 0.95
142_V 169_A 1.469 0.95
157_F 184_T 1.465 0.95
50_L 79_V 1.413 0.93
25_V 29_A 1.393 0.93
48_G 51_E 1.36 0.91
93_R 96_Q 1.359 0.91
95_K 109_N 1.351 0.91
69_R 84_Q 1.335 0.90
171_A 185_T 1.326 0.90
58_L 94_A 1.325 0.90
53_R 101_V 1.317 0.89
80_L 159_M 1.307 0.89
167_A 171_A 1.3 0.89
132_V 156_V 1.283 0.88
37_D 44_Q 1.282 0.88
156_V 180_V 1.281 0.88
149_V 158_L 1.28 0.88
124_N 131_K 1.274 0.87
155_E 184_T 1.273 0.87
80_L 157_F 1.252 0.86
50_L 74_A 1.248 0.86
50_L 104_A 1.221 0.84
172_D 175_S 1.217 0.84
84_Q 117_I 1.217 0.84
9_V 12_S 1.207 0.83
75_Y 159_M 1.199 0.83
137_L 144_S 1.198 0.83
130_T 134_S 1.196 0.82
164_E 191_K 1.192 0.82
142_V 147_V 1.185 0.82
167_A 187_F 1.183 0.81
98_A 107_V 1.181 0.81
127_W 131_K 1.174 0.81
81_L 98_A 1.17 0.80
70_I 81_L 1.147 0.79
34_A 41_V 1.143 0.78
78_K 106_E 1.141 0.78
84_Q 112_R 1.131 0.77
42_G 53_R 1.128 0.77
69_R 152_E 1.125 0.77
39_R 75_Y 1.12 0.76
84_Q 152_E 1.117 0.76
31_G 35_A 1.116 0.76
27_T 32_T 1.11 0.75
128_I 156_V 1.105 0.75
71_N 84_Q 1.104 0.75
107_V 126_T 1.104 0.75
88_A 91_S 1.104 0.75
139_S 169_A 1.103 0.75
51_E 55_N 1.098 0.74
161_L 188_T 1.097 0.74
42_G 101_V 1.096 0.74
127_W 130_T 1.087 0.73
18_G 21_A 1.085 0.73
73_T 150_T 1.084 0.73
43_T 50_L 1.083 0.73
72_V 159_M 1.054 0.70
48_G 74_A 1.052 0.70
24_V 27_T 1.05 0.69
133_R 149_V 1.039 0.68
25_V 28_A 1.037 0.68
164_E 189_F 1.029 0.67
42_G 166_E 1.028 0.67
55_N 59_S 1.026 0.67
117_I 122_A 1.023 0.66
170_A 180_V 1.019 0.66
91_S 111_I 1.015 0.66
96_Q 107_V 1.008 0.65
162_V 167_A 1.001 0.64
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2kgsA10.638799.90.621Contact Map0.4
4alzA10.680699.70.68Contact Map0.369
2l26A10.753998.10.84Contact Map0.406
3zbiC140.251344.10.938Contact Map0.128
3tlkA30.900518.70.948Contact Map0.085
2yp6A40.832513.80.951Contact Map0.144
2qgmA10.879613.10.952Contact Map0.098
3cq1A10.4712110.953Contact Map0.616
1uwdA10.46610.50.954Contact Map0.527
4fajA10.79067.90.956Contact Map0.028
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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