| UniProt: | P60844 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13270 | ||
| Length: | 231 (228) | ||
| Sequences: | 2985 | ||
| Seq/Len: | 13.09 |
| AQPZ
Paralog alert: 0.53 [within 20: 0.04] - ratio of genomes with paralogs Cluster includes: AQPZ GLPF |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 9_C | 94_V | 4.103 | 1.00 | |
| 67_T | 81_V | 3.722 | 1.00 | |
| 139_L | 218_I | 3.634 | 1.00 | |
| 71_W | 78_A | 3.52 | 1.00 | |
| 13_F | 98_L | 3.435 | 1.00 | |
| 139_L | 214_V | 3.303 | 1.00 | |
| 9_C | 90_V | 3.057 | 1.00 | |
| 135_L | 211_V | 3.018 | 1.00 | |
| 71_W | 81_V | 2.971 | 1.00 | |
| 5_L | 87_A | 2.897 | 1.00 | |
| 13_F | 95_A | 2.846 | 1.00 | |
| 5_L | 83_G | 2.769 | 1.00 | |
| 148_V | 169_A | 2.747 | 1.00 | |
| 135_L | 139_L | 2.672 | 1.00 | |
| 72_A | 217_I | 2.665 | 1.00 | |
| 143_A | 219_G | 2.572 | 1.00 | |
| 141_L | 177_S | 2.536 | 1.00 | |
| 44_G | 171_T | 2.504 | 1.00 | |
| 4_K | 80_E | 2.43 | 1.00 | |
| 191_T | 195_I | 2.305 | 1.00 | |
| 85_V | 213_I | 2.172 | 1.00 | |
| 184_S | 190_S | 2.152 | 1.00 | |
| 68_I | 213_I | 2.112 | 1.00 | |
| 54_V | 62_F | 2.039 | 1.00 | |
| 213_I | 217_I | 1.928 | 1.00 | |
| 48_L | 167_G | 1.926 | 1.00 | |
| 19_G | 43_F | 1.862 | 1.00 | |
| 174_H | 183_T | 1.845 | 1.00 | |
| 174_H | 178_I | 1.824 | 1.00 | |
| 141_L | 185_V | 1.818 | 1.00 | |
| 11_G | 62_F | 1.809 | 1.00 | |
| 61_H | 84_Y | 1.742 | 1.00 | |
| 50_M | 54_V | 1.719 | 1.00 | |
| 68_I | 85_V | 1.709 | 1.00 | |
| 206_W | 210_V | 1.693 | 1.00 | |
| 47_V | 170_L | 1.684 | 1.00 | |
| 191_T | 209_W | 1.587 | 1.00 | |
| 205_L | 209_W | 1.582 | 1.00 | |
| 215_G | 219_G | 1.563 | 1.00 | |
| 154_D | 223_Y | 1.514 | 1.00 | |
| 97_A | 196_F | 1.483 | 1.00 | |
| 143_A | 222_I | 1.479 | 1.00 | |
| 170_L | 185_V | 1.478 | 1.00 | |
| 93_I | 192_A | 1.473 | 1.00 | |
| 66_V | 149_I | 1.469 | 1.00 | |
| 173_I | 185_V | 1.464 | 1.00 | |
| 146_L | 216_G | 1.446 | 1.00 | |
| 17_F | 98_L | 1.421 | 1.00 | |
| 87_A | 91_G | 1.42 | 1.00 | |
| 134_A | 181_T | 1.41 | 1.00 | |
| 76_F | 81_V | 1.401 | 0.99 | |
| 78_A | 81_V | 1.394 | 0.99 | |
| 67_T | 88_Q | 1.375 | 0.99 | |
| 37_A | 41_L | 1.358 | 0.99 | |
| 97_A | 101_L | 1.348 | 0.99 | |
| 69_G | 73_G | 1.346 | 0.99 | |
| 70_L | 76_F | 1.329 | 0.99 | |
| 142_S | 216_G | 1.305 | 0.99 | |
| 67_T | 76_F | 1.305 | 0.99 | |
| 129_Y | 201_A | 1.299 | 0.99 | |
| 18_G | 46_T | 1.279 | 0.99 | |
| 138_E | 181_T | 1.278 | 0.99 | |
| 137_V | 180_V | 1.256 | 0.99 | |
| 190_S | 194_A | 1.251 | 0.99 | |
| 74_G | 224_R | 1.247 | 0.99 | |
| 25_L | 180_V | 1.243 | 0.98 | |
| 54_V | 60_G | 1.225 | 0.98 | |
| 143_A | 218_I | 1.224 | 0.98 | |
| 93_I | 196_F | 1.224 | 0.98 | |
| 92_G | 96_A | 1.224 | 0.98 | |
| 96_A | 193_V | 1.223 | 0.98 | |
| 143_A | 147_L | 1.221 | 0.98 | |
| 102_I | 137_V | 1.219 | 0.98 | |
| 23_A | 39_V | 1.203 | 0.98 | |
| 109_F | 121_Y | 1.188 | 0.98 | |
| 137_V | 141_L | 1.185 | 0.98 | |
| 137_V | 181_T | 1.181 | 0.98 | |
| 197_Q | 200_W | 1.173 | 0.98 | |
| 51_A | 163_P | 1.161 | 0.97 | |
| 98_L | 140_V | 1.153 | 0.97 | |
| 135_L | 207_F | 1.153 | 0.97 | |
| 14_W | 144_G | 1.146 | 0.97 | |
| 139_L | 215_G | 1.144 | 0.97 | |
| 89_V | 209_W | 1.139 | 0.97 | |
| 7_A | 57_I | 1.135 | 0.97 | |
| 2_F | 5_L | 1.13 | 0.97 | |
| 48_L | 164_I | 1.114 | 0.96 | |
| 164_I | 168_L | 1.113 | 0.96 | |
| 15_L | 47_V | 1.108 | 0.96 | |
| 89_V | 191_T | 1.106 | 0.96 | |
| 13_F | 94_V | 1.104 | 0.96 | |
| 50_M | 62_F | 1.099 | 0.96 | |
| 53_A | 148_V | 1.097 | 0.96 | |
| 71_W | 76_F | 1.086 | 0.96 | |
| 20_C | 99_L | 1.086 | 0.96 | |
| 211_V | 215_G | 1.082 | 0.96 | |
| 78_A | 82_V | 1.076 | 0.95 | |
| 132_L | 136_V | 1.076 | 0.95 | |
| 139_L | 211_V | 1.067 | 0.95 | |
| 92_G | 192_A | 1.064 | 0.95 | |
| 16_V | 20_C | 1.061 | 0.95 | |
| 23_A | 27_A | 1.059 | 0.95 | |
| 135_L | 210_V | 1.056 | 0.95 | |
| 145_F | 170_L | 1.053 | 0.95 | |
| 191_T | 205_L | 1.045 | 0.94 | |
| 94_V | 97_A | 1.023 | 0.93 | |
| 162_A | 166_I | 1.013 | 0.93 | |
| 32_L | 36_F | 1.01 | 0.93 | |
| 21_G | 99_L | 1.01 | 0.93 | |
| 104_S | 110_D | 1.01 | 0.93 | |
| 41_L | 171_T | 1.009 | 0.93 | |
| 131_M | 207_F | 1.008 | 0.93 | |
| 51_A | 66_V | 1.002 | 0.92 | |
| 85_V | 89_V | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2o9gA | 1 | 1 | 100 | 0.057 | Contact Map | 0.808 |
| 3llqA | 2 | 0.987 | 100 | 0.079 | Contact Map | 0.825 |
| 1ldfA | 1 | 0.9957 | 100 | 0.119 | Contact Map | 0.804 |
| 3iyzA | 1 | 0.9481 | 100 | 0.125 | Contact Map | 0.089 |
| 3c02A | 1 | 0.974 | 100 | 0.127 | Contact Map | 0.806 |
| 1j4nA | 1 | 0.9524 | 100 | 0.133 | Contact Map | 0.783 |
| 2zz9A | 1 | 0.9481 | 100 | 0.134 | Contact Map | 0.791 |
| 3cn5A | 1 | 0.9654 | 100 | 0.14 | Contact Map | 0.808 |
| 2b6oA | 1 | 0.9351 | 100 | 0.14 | Contact Map | 0.824 |
| 3gd8A | 1 | 0.9394 | 100 | 0.142 | Contact Map | 0.835 |
Sequence Conservation (Image Generated using WebLogo v3)