| UniProt: | P0AER0 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10396 | ||
| Length: | 281 (257) | ||
| Sequences: | 2692 | ||
| Seq/Len: | 10.47 |
| GLPF
Paralog alert: 0.52 [within 20: 0.04] - ratio of genomes with paralogs Cluster includes: AQPZ GLPF |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 15_F | 99_C | 4.543 | 1.00 | |
| 153_M | 246_V | 3.872 | 1.00 | |
| 72_T | 86_V | 3.764 | 1.00 | |
| 76_W | 83_K | 3.664 | 1.00 | |
| 153_M | 242_V | 3.531 | 1.00 | |
| 19_G | 103_L | 3.521 | 1.00 | |
| 15_F | 95_A | 3.383 | 1.00 | |
| 149_F | 239_G | 3.27 | 1.00 | |
| 162_L | 186_L | 3.136 | 1.00 | |
| 77_L | 245_I | 3.112 | 1.00 | |
| 149_F | 153_M | 3.067 | 1.00 | |
| 76_W | 86_V | 2.894 | 1.00 | |
| 49_G | 188_A | 2.89 | 1.00 | |
| 11_C | 88_P | 2.872 | 1.00 | |
| 157_A | 247_G | 2.854 | 1.00 | |
| 19_G | 100_A | 2.838 | 1.00 | |
| 11_C | 92_S | 2.809 | 1.00 | |
| 208_F | 212_V | 2.655 | 1.00 | |
| 73_I | 241_I | 2.533 | 1.00 | |
| 10_Q | 85_K | 2.468 | 1.00 | |
| 90_I | 241_I | 2.396 | 1.00 | |
| 155_I | 194_M | 2.38 | 1.00 | |
| 59_T | 67_L | 2.166 | 1.00 | |
| 201_A | 207_D | 2.03 | 1.00 | |
| 53_A | 184_G | 2.007 | 1.00 | |
| 73_I | 90_I | 1.996 | 1.00 | |
| 191_G | 200_F | 1.973 | 1.00 | |
| 234_L | 238_F | 1.962 | 1.00 | |
| 191_G | 195_G | 1.952 | 1.00 | |
| 241_I | 245_I | 1.932 | 1.00 | |
| 17_G | 67_L | 1.919 | 1.00 | |
| 25_G | 48_W | 1.907 | 1.00 | |
| 208_F | 237_L | 1.847 | 1.00 | |
| 112_F | 134_T | 1.837 | 1.00 | |
| 55_A | 59_T | 1.817 | 1.00 | |
| 155_I | 202_M | 1.809 | 1.00 | |
| 52_V | 187_I | 1.74 | 1.00 | |
| 151_V | 197_L | 1.695 | 1.00 | |
| 66_H | 89_F | 1.683 | 1.00 | |
| 243_G | 247_G | 1.65 | 1.00 | |
| 83_K | 86_V | 1.627 | 1.00 | |
| 71_V | 163_I | 1.615 | 1.00 | |
| 160_M | 244_A | 1.611 | 1.00 | |
| 23_F | 103_L | 1.587 | 1.00 | |
| 102_A | 213_F | 1.581 | 1.00 | |
| 98_F | 216_L | 1.549 | 1.00 | |
| 142_H | 229_D | 1.542 | 1.00 | |
| 98_F | 209_G | 1.539 | 1.00 | |
| 148_A | 198_T | 1.531 | 1.00 | |
| 190_I | 202_M | 1.527 | 1.00 | |
| 233_F | 237_L | 1.502 | 1.00 | |
| 101_A | 210_P | 1.497 | 1.00 | |
| 157_A | 250_A | 1.49 | 1.00 | |
| 109_Y | 113_F | 1.474 | 1.00 | |
| 187_I | 202_M | 1.467 | 1.00 | |
| 167_T | 183_I | 1.463 | 1.00 | |
| 29_V | 33_K | 1.443 | 1.00 | |
| 168_D | 251_Y | 1.437 | 1.00 | |
| 59_T | 65_A | 1.422 | 1.00 | |
| 102_A | 106_G | 1.418 | 1.00 | |
| 75_L | 81_F | 1.409 | 1.00 | |
| 46_V | 188_A | 1.398 | 0.99 | |
| 24_F | 51_G | 1.394 | 0.99 | |
| 92_S | 96_G | 1.369 | 0.99 | |
| 74_A | 78_F | 1.367 | 0.99 | |
| 98_F | 213_F | 1.363 | 0.99 | |
| 151_V | 155_I | 1.342 | 0.99 | |
| 152_E | 198_T | 1.34 | 0.99 | |
| 81_F | 86_V | 1.334 | 0.99 | |
| 97_A | 101_A | 1.333 | 0.99 | |
| 139_P | 148_A | 1.301 | 0.99 | |
| 29_V | 44_I | 1.298 | 0.99 | |
| 72_T | 93_Q | 1.286 | 0.99 | |
| 149_F | 235_V | 1.27 | 0.99 | |
| 214_A | 228_R | 1.267 | 0.99 | |
| 153_M | 243_G | 1.265 | 0.99 | |
| 7_L | 11_C | 1.259 | 0.99 | |
| 45_S | 192_A | 1.242 | 0.98 | |
| 208_F | 233_F | 1.239 | 0.98 | |
| 53_A | 181_L | 1.232 | 0.98 | |
| 19_G | 99_C | 1.225 | 0.98 | |
| 50_L | 185_L | 1.214 | 0.98 | |
| 157_A | 246_V | 1.204 | 0.98 | |
| 37_A | 41_Q | 1.188 | 0.98 | |
| 79_A | 252_R | 1.186 | 0.98 | |
| 94_V | 237_L | 1.18 | 0.98 | |
| 157_A | 161_G | 1.178 | 0.98 | |
| 145_F | 235_V | 1.164 | 0.97 | |
| 156_T | 244_A | 1.158 | 0.97 | |
| 149_F | 238_F | 1.155 | 0.97 | |
| 153_M | 239_G | 1.15 | 0.97 | |
| 103_L | 154_V | 1.148 | 0.97 | |
| 107_L | 197_L | 1.147 | 0.97 | |
| 26_V | 104_V | 1.144 | 0.97 | |
| 55_A | 67_L | 1.123 | 0.97 | |
| 13_A | 62_V | 1.116 | 0.96 | |
| 83_K | 87_I | 1.112 | 0.96 | |
| 146_V | 150_A | 1.11 | 0.96 | |
| 57_Y | 178_L | 1.108 | 0.96 | |
| 50_L | 189_V | 1.097 | 0.96 | |
| 239_G | 243_G | 1.093 | 0.96 | |
| 107_L | 151_V | 1.09 | 0.96 | |
| 151_V | 198_T | 1.088 | 0.96 | |
| 21_L | 52_V | 1.088 | 0.96 | |
| 8_K | 11_C | 1.085 | 0.96 | |
| 97_A | 209_G | 1.079 | 0.95 | |
| 87_I | 91_V | 1.068 | 0.95 | |
| 181_L | 185_L | 1.064 | 0.95 | |
| 20_L | 158_I | 1.064 | 0.95 | |
| 207_D | 211_K | 1.063 | 0.95 | |
| 179_A | 183_I | 1.056 | 0.95 | |
| 56_I | 180_P | 1.047 | 0.94 | |
| 63_S | 89_F | 1.046 | 0.94 | |
| 70_A | 244_A | 1.041 | 0.94 | |
| 69_P | 205_A | 1.038 | 0.94 | |
| 22_I | 26_V | 1.032 | 0.94 | |
| 22_I | 104_V | 1.032 | 0.94 | |
| 56_I | 71_V | 1.029 | 0.94 | |
| 58_L | 162_L | 1.025 | 0.93 | |
| 70_A | 204_P | 1.016 | 0.93 | |
| 137_T | 201_A | 1.013 | 0.93 | |
| 76_W | 87_I | 1.01 | 0.93 | |
| 213_F | 217_A | 1.007 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1ldfA | 1 | 1 | 100 | 0.134 | Contact Map | 0.799 |
| 3c02A | 1 | 0.9075 | 100 | 0.241 | Contact Map | 0.772 |
| 1j4nA | 1 | 0.8861 | 100 | 0.287 | Contact Map | 0.779 |
| 3iyzA | 1 | 0.8754 | 100 | 0.291 | Contact Map | 0.079 |
| 2b6oA | 1 | 0.879 | 100 | 0.294 | Contact Map | 0.82 |
| 2zz9A | 1 | 0.8754 | 100 | 0.301 | Contact Map | 0.782 |
| 3d9sA | 4 | 0.879 | 100 | 0.301 | Contact Map | 0.875 |
| 3cn5A | 1 | 0.8719 | 100 | 0.308 | Contact Map | 0.78 |
| 3zojA | 1 | 0.8363 | 100 | 0.314 | Contact Map | 0.739 |
| 2f2bA | 1 | 0.8149 | 100 | 0.315 | Contact Map | 0.808 |
Sequence Conservation (Image Generated using WebLogo v3)