| UniProt: | P60546 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10965 | ||
| Length: | 207 (199) | ||
| Sequences: | 2626 | ||
| Seq/Len: | 13.20 |
| KGUA
Paralog alert: 0.30 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: KGUA PHNN |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 130_E | 133_R | 4.139 | 1.00 | |
| 132_D | 136_R | 3.993 | 1.00 | |
| 61_E | 64_E | 2.767 | 1.00 | |
| 136_R | 143_E | 2.741 | 1.00 | |
| 39_H | 85_S | 2.693 | 1.00 | |
| 59_H | 63_K | 2.612 | 1.00 | |
| 64_E | 68_R | 2.562 | 1.00 | |
| 49_V | 52_E | 2.52 | 1.00 | |
| 167_I | 175_A | 2.487 | 1.00 | |
| 76_E | 79_G | 2.342 | 1.00 | |
| 65_M | 70_A | 2.314 | 1.00 | |
| 87_E | 91_Q | 2.293 | 1.00 | |
| 20_L | 179_L | 2.27 | 1.00 | |
| 63_K | 81_Y | 2.236 | 1.00 | |
| 27_T | 180_K | 2.177 | 1.00 | |
| 174_T | 178_D | 2.145 | 1.00 | |
| 59_H | 81_Y | 2.124 | 1.00 | |
| 77_V | 104_D | 2.089 | 1.00 | |
| 39_H | 57_V | 2.063 | 1.00 | |
| 70_A | 87_E | 2.06 | 1.00 | |
| 66_I | 74_H | 2.048 | 1.00 | |
| 78_F | 152_Q | 1.989 | 1.00 | |
| 50_H | 55_F | 1.984 | 1.00 | |
| 58_N | 61_E | 1.98 | 1.00 | |
| 143_E | 147_A | 1.967 | 1.00 | |
| 86_R | 90_E | 1.947 | 1.00 | |
| 59_H | 76_E | 1.914 | 1.00 | |
| 19_S | 172_F | 1.911 | 1.00 | |
| 171_D | 174_T | 1.892 | 1.00 | |
| 20_L | 123_I | 1.873 | 1.00 | |
| 132_D | 147_A | 1.862 | 1.00 | |
| 91_Q | 95_T | 1.852 | 1.00 | |
| 10_S | 163_Y | 1.852 | 1.00 | |
| 63_K | 67_S | 1.805 | 1.00 | |
| 23_A | 176_L | 1.782 | 1.00 | |
| 76_E | 81_Y | 1.719 | 1.00 | |
| 90_E | 94_A | 1.714 | 1.00 | |
| 75_A | 106_Q | 1.694 | 1.00 | |
| 59_H | 80_N | 1.654 | 1.00 | |
| 34_Q | 97_V | 1.651 | 1.00 | |
| 57_V | 65_M | 1.581 | 1.00 | |
| 112_R | 164_D | 1.566 | 1.00 | |
| 109_Q | 162_E | 1.558 | 1.00 | |
| 142_S | 145_V | 1.483 | 1.00 | |
| 88_A | 92_V | 1.473 | 1.00 | |
| 23_A | 26_K | 1.465 | 1.00 | |
| 11_A | 15_A | 1.434 | 1.00 | |
| 147_A | 151_A | 1.396 | 0.99 | |
| 63_K | 66_I | 1.387 | 0.99 | |
| 88_A | 91_Q | 1.384 | 0.99 | |
| 167_I | 179_L | 1.372 | 0.99 | |
| 165_Y | 182_I | 1.37 | 0.99 | |
| 18_S | 102_D | 1.351 | 0.99 | |
| 49_V | 53_H | 1.35 | 0.99 | |
| 159_H | 162_E | 1.333 | 0.99 | |
| 28_Q | 180_K | 1.32 | 0.99 | |
| 55_F | 88_A | 1.3 | 0.99 | |
| 66_I | 81_Y | 1.286 | 0.99 | |
| 127_S | 130_E | 1.283 | 0.99 | |
| 20_L | 176_L | 1.228 | 0.98 | |
| 21_I | 102_D | 1.211 | 0.98 | |
| 23_A | 27_T | 1.207 | 0.98 | |
| 103_I | 111_I | 1.202 | 0.98 | |
| 78_F | 104_D | 1.19 | 0.98 | |
| 85_S | 88_A | 1.184 | 0.98 | |
| 141_D | 146_I | 1.175 | 0.98 | |
| 152_Q | 155_A | 1.168 | 0.97 | |
| 50_H | 61_E | 1.165 | 0.97 | |
| 9_V | 21_I | 1.163 | 0.97 | |
| 172_F | 176_L | 1.159 | 0.97 | |
| 22_Q | 53_H | 1.138 | 0.97 | |
| 34_Q | 92_V | 1.138 | 0.97 | |
| 90_E | 115_M | 1.134 | 0.97 | |
| 57_V | 61_E | 1.132 | 0.97 | |
| 133_R | 137_G | 1.129 | 0.97 | |
| 28_Q | 32_D | 1.116 | 0.96 | |
| 64_E | 67_S | 1.113 | 0.96 | |
| 167_I | 182_I | 1.103 | 0.96 | |
| 22_Q | 26_K | 1.102 | 0.96 | |
| 61_E | 65_M | 1.097 | 0.96 | |
| 35_V | 102_D | 1.096 | 0.96 | |
| 7_Y | 119_R | 1.089 | 0.96 | |
| 101_L | 111_I | 1.088 | 0.96 | |
| 160_Y | 166_L | 1.083 | 0.96 | |
| 92_V | 97_V | 1.074 | 0.95 | |
| 23_A | 173_D | 1.07 | 0.95 | |
| 11_A | 18_S | 1.061 | 0.95 | |
| 105_W | 159_H | 1.06 | 0.95 | |
| 9_V | 179_L | 1.055 | 0.95 | |
| 18_S | 53_H | 1.043 | 0.94 | |
| 21_I | 100_F | 1.036 | 0.94 | |
| 60_D | 63_K | 1.031 | 0.94 | |
| 124_L | 157_M | 1.029 | 0.94 | |
| 69_D | 114_K | 1.027 | 0.94 | |
| 57_V | 85_S | 1.027 | 0.94 | |
| 170_D | 174_T | 1.014 | 0.93 | |
| 27_T | 177_T | 1.006 | 0.93 | |
| 92_V | 95_T | 1.004 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2xkxA | 2 | 0.9275 | 100 | 0.187 | Contact Map | 0.332 |
| 1kjwA | 1 | 0.9179 | 100 | 0.201 | Contact Map | 0.665 |
| 3tvtA | 1 | 0.9275 | 100 | 0.224 | Contact Map | 0.724 |
| 4deyA | 1 | 0.9275 | 100 | 0.272 | Contact Map | 0.471 |
| 1s96A | 2 | 1 | 100 | 0.313 | Contact Map | 0.75 |
| 3tszA | 1 | 0.7681 | 100 | 0.443 | Contact Map | 0.554 |
| 1lvgA | 1 | 0.942 | 100 | 0.455 | Contact Map | 0.722 |
| 1z6gA | 1 | 0.942 | 100 | 0.468 | Contact Map | 0.581 |
| 3tauA | 2 | 0.9855 | 100 | 0.468 | Contact Map | 0.717 |
| 3shwA | 1 | 0.8164 | 100 | 0.478 | Contact Map | 0.557 |
Sequence Conservation (Image Generated using WebLogo v3)