| UniProt: | P46859 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12629 | ||
| Length: | 175 (165) | ||
| Sequences: | 816 | ||
| Seq/Len: | 4.95 |
| GNTK
Paralog alert: 0.27 [within 20: 0.00] - ratio of genomes with paralogs Cluster includes: GNTK IDNK |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 114_F | 135_V | 3.894 | 1.00 | |
| 130_K | 133_M | 3.674 | 1.00 | |
| 154_V | 163_V | 3.662 | 1.00 | |
| 117_I | 138_F | 3.655 | 1.00 | |
| 45_R | 49_E | 3.494 | 1.00 | |
| 42_L | 69_L | 2.927 | 1.00 | |
| 111_K | 143_E | 2.919 | 1.00 | |
| 38_D | 86_V | 2.911 | 1.00 | |
| 112_G | 156_I | 2.902 | 1.00 | |
| 135_V | 139_E | 2.808 | 1.00 | |
| 67_Q | 97_L | 2.792 | 1.00 | |
| 50_K | 61_D | 2.595 | 1.00 | |
| 144_P | 151_V | 2.519 | 1.00 | |
| 44_P | 47_N | 2.394 | 1.00 | |
| 121_L | 134_L | 2.374 | 1.00 | |
| 112_G | 117_I | 2.126 | 1.00 | |
| 31_Q | 165_A | 2.044 | 1.00 | |
| 34_A | 82_V | 1.91 | 1.00 | |
| 17_S | 134_L | 1.885 | 1.00 | |
| 37_L | 42_L | 1.845 | 1.00 | |
| 109_Y | 143_E | 1.813 | 1.00 | |
| 96_D | 99_R | 1.774 | 1.00 | |
| 69_L | 85_I | 1.744 | 1.00 | |
| 37_L | 72_A | 1.698 | 0.99 | |
| 27_E | 160_L | 1.663 | 0.99 | |
| 36_F | 86_V | 1.65 | 0.99 | |
| 23_A | 160_L | 1.638 | 0.99 | |
| 12_V | 107_F | 1.603 | 0.99 | |
| 119_S | 123_A | 1.596 | 0.99 | |
| 39_G | 85_I | 1.554 | 0.99 | |
| 22_S | 26_S | 1.551 | 0.99 | |
| 99_R | 107_F | 1.546 | 0.99 | |
| 159_P | 162_G | 1.51 | 0.99 | |
| 109_Y | 144_P | 1.481 | 0.98 | |
| 66_L | 94_Y | 1.42 | 0.98 | |
| 44_P | 68_A | 1.386 | 0.97 | |
| 73_A | 85_I | 1.385 | 0.97 | |
| 25_A | 36_F | 1.385 | 0.97 | |
| 24_V | 163_V | 1.375 | 0.97 | |
| 166_S | 170_V | 1.354 | 0.97 | |
| 113_D | 116_V | 1.331 | 0.96 | |
| 113_D | 157_D | 1.272 | 0.95 | |
| 44_P | 48_I | 1.265 | 0.94 | |
| 111_K | 153_V | 1.222 | 0.93 | |
| 63_K | 67_Q | 1.217 | 0.93 | |
| 148_E | 151_V | 1.213 | 0.93 | |
| 64_P | 134_L | 1.212 | 0.93 | |
| 158_Q | 162_G | 1.205 | 0.92 | |
| 15_G | 21_K | 1.194 | 0.92 | |
| 72_A | 83_S | 1.188 | 0.92 | |
| 25_A | 38_D | 1.154 | 0.90 | |
| 114_F | 118_E | 1.152 | 0.90 | |
| 116_V | 157_D | 1.13 | 0.89 | |
| 15_G | 20_G | 1.094 | 0.86 | |
| 11_Y | 108_I | 1.083 | 0.86 | |
| 70_N | 101_G | 1.082 | 0.86 | |
| 18_G | 121_L | 1.064 | 0.84 | |
| 121_L | 129_F | 1.063 | 0.84 | |
| 66_L | 87_C | 1.055 | 0.84 | |
| 52_A | 128_F | 1.055 | 0.84 | |
| 108_I | 167_T | 1.052 | 0.83 | |
| 29_A | 84_L | 1.05 | 0.83 | |
| 117_I | 156_I | 1.043 | 0.83 | |
| 160_L | 164_V | 1.042 | 0.83 | |
| 112_G | 116_V | 1.037 | 0.82 | |
| 114_F | 138_F | 1.037 | 0.82 | |
| 61_D | 66_L | 1.037 | 0.82 | |
| 60_D | 63_K | 1.023 | 0.81 | |
| 71_D | 75_A | 1.017 | 0.80 | |
| 31_Q | 164_V | 1.012 | 0.80 | |
| 49_E | 52_A | 1.008 | 0.80 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1knqA | 2 | 1 | 100 | 0.618 | Contact Map | 0.726 |
| 4eunA | 1 | 0.9943 | 100 | 0.619 | Contact Map | 0.647 |
| 3t61A | 2 | 0.9714 | 99.9 | 0.64 | Contact Map | 0.722 |
| 2rhmA | 4 | 0.9429 | 99.9 | 0.692 | Contact Map | 0.42 |
| 2gksA | 2 | 0.9429 | 99.9 | 0.699 | Contact Map | 0.648 |
| 1m8pA | 3 | 0.9429 | 99.8 | 0.704 | Contact Map | 0.708 |
| 1m7gA | 4 | 0.9371 | 99.8 | 0.705 | Contact Map | 0.652 |
| 1e6cA | 2 | 0.9029 | 99.8 | 0.71 | Contact Map | 0.532 |
| 2yvuA | 2 | 0.9314 | 99.8 | 0.717 | Contact Map | 0.658 |
| 1viaA | 2 | 0.92 | 99.8 | 0.719 | Contact Map | 0.569 |
Sequence Conservation (Image Generated using WebLogo v3)