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RIMN - tRNA threonylcarbamoyladenosine biosynthesis protein RimN
UniProt: P45748 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12840
Length: 190 (185)
Sequences: 2857
Seq/Len: 15.44
RIMN
Paralog alert: 0.46 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: RIMN YCIO
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
16_V 21_R 5.591 1.00
25_Y 34_G 3.947 1.00
36_D 39_S 3.313 1.00
11_A 130_A 2.572 1.00
20_E 39_S 2.443 1.00
15_D 19_E 2.348 1.00
63_A 67_Q 2.24 1.00
64_N 129_Q 2.213 1.00
25_Y 124_V 2.179 1.00
36_D 133_K 2.102 1.00
37_P 60_L 2.062 1.00
56_K 143_S 2.001 1.00
69_K 82_R 1.958 1.00
17_L 131_Y 1.905 1.00
155_R 159_G 1.902 1.00
22_V 49_L 1.893 1.00
63_A 128_C 1.868 1.00
35_C 42_A 1.85 1.00
24_A 162_F 1.825 1.00
126_A 129_Q 1.703 1.00
34_G 135_L 1.702 1.00
40_E 104_P 1.692 1.00
10_I 130_A 1.66 1.00
24_A 154_V 1.658 1.00
16_V 163_P 1.587 1.00
123_L 167_G 1.583 1.00
62_A 68_L 1.573 1.00
72_I 97_F 1.564 1.00
142_L 157_Q 1.559 1.00
180_D 183_T 1.491 1.00
96_V 187_F 1.466 1.00
63_A 129_Q 1.457 1.00
150_T 153_E 1.454 1.00
45_R 48_E 1.426 1.00
61_I 137_S 1.424 1.00
44_M 48_E 1.405 0.99
65_Y 86_F 1.391 0.99
38_D 133_K 1.387 0.99
82_R 86_F 1.373 0.99
67_Q 70_P 1.373 0.99
71_Y 116_V 1.365 0.99
12_A 15_D 1.353 0.99
49_L 161_A 1.35 0.99
155_R 164_V 1.342 0.99
14_I 131_Y 1.341 0.99
25_Y 137_S 1.333 0.99
25_Y 127_L 1.328 0.99
123_L 165_V 1.312 0.99
14_I 18_N 1.305 0.99
145_L 157_Q 1.295 0.99
21_R 45_R 1.293 0.99
46_L 136_V 1.288 0.99
40_E 44_M 1.283 0.99
118_V 125_V 1.282 0.99
66_E 69_K 1.271 0.99
94_T 115_A 1.27 0.99
17_L 135_L 1.261 0.99
62_A 118_V 1.261 0.99
122_P 126_A 1.259 0.99
49_L 158_F 1.252 0.99
47_L 54_V 1.246 0.98
85_I 95_F 1.242 0.98
65_Y 118_V 1.239 0.98
77_L 85_I 1.22 0.98
74_D 98_P 1.219 0.98
38_D 104_P 1.207 0.98
125_V 129_Q 1.196 0.98
78_T 81_Q 1.194 0.98
40_E 106_W 1.18 0.98
99_A 108_T 1.143 0.97
81_Q 85_I 1.141 0.97
14_I 130_A 1.14 0.97
11_A 15_D 1.133 0.97
127_L 165_V 1.133 0.97
73_D 98_P 1.124 0.97
99_A 105_R 1.111 0.96
142_L 161_A 1.111 0.96
24_A 151_V 1.104 0.96
15_D 18_N 1.104 0.96
126_A 130_A 1.103 0.96
150_T 169_T 1.094 0.96
52_R 141_N 1.085 0.96
59_I 115_A 1.067 0.95
96_V 113_S 1.059 0.95
154_V 164_V 1.056 0.95
72_I 116_V 1.049 0.94
152_D 156_A 1.044 0.94
34_G 127_L 1.037 0.94
119_T 125_V 1.022 0.93
44_M 54_V 1.021 0.93
65_Y 85_I 1.011 0.93
39_S 42_A 1.007 0.93
79_D 82_R 1.002 0.92
120_D 171_G 1.001 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2eqaA10.98951000.085Contact Map0.848
1hruA20.98951000.143Contact Map0.731
1k7jA10.97891000.143Contact Map0.749
1jcuA10.96841000.155Contact Map0.375
3l7vA10.97371000.161Contact Map0.513
3vthA20.96841000.192Contact Map0.719
4g9iA60.96841000.217Contact Map0.74
3ttcA10.93681000.259Contact Map0.63
3venA10.847496.60.876Contact Map0.554
1r18A10.315820.60.947Contact Map0.125
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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