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OPENSEQ.org

PTPD - N-acetylgalactosamine permease IID component
UniProt: P42911 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12771
Length: 263 (258)
Sequences: 703
Seq/Len: 2.72

PTPD
Paralog alert: 0.75 [within 20: 0.16] - ratio of genomes with paralogs
Cluster includes: PTND PTPD
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
214_D 217_D 3.823 1.00
66_T 103_A 3.764 1.00
48_D 52_G 3.174 1.00
42_L 53_L 3.127 1.00
242_H 245_L 3.049 1.00
248_G 252_V 3.041 1.00
9_D 44_K 2.717 1.00
6_S 9_D 2.687 1.00
41_I 79_I 2.415 1.00
50_K 54_S 2.359 1.00
135_I 139_A 2.326 1.00
122_C 133_G 2.254 1.00
211_L 214_D 2.181 1.00
38_M 42_L 2.172 1.00
8_K 12_R 2.097 1.00
227_A 231_L 2.097 1.00
253_L 257_C 2.015 1.00
136_L 140_V 1.994 1.00
64_I 71_V 1.895 0.99
257_C 263_L 1.895 0.99
231_L 234_Y 1.87 0.99
213_Q 217_D 1.838 0.99
119_A 137_F 1.835 0.99
5_I 41_I 1.824 0.99
74_L 103_A 1.763 0.98
5_I 9_D 1.745 0.98
64_I 74_L 1.744 0.98
34_F 78_L 1.724 0.98
21_Q 24_F 1.714 0.98
60_N 95_K 1.641 0.97
83_E 156_Y 1.632 0.97
139_A 143_L 1.631 0.97
115_L 137_F 1.615 0.97
55_A 88_R 1.591 0.97
197_V 224_L 1.574 0.96
48_D 51_P 1.569 0.96
256_V 260_F 1.514 0.95
241_A 249_V 1.509 0.95
10_I 153_H 1.498 0.95
10_I 152_T 1.482 0.94
232_M 250_T 1.474 0.94
16_R 36_W 1.462 0.94
5_I 79_I 1.459 0.94
66_T 74_L 1.451 0.93
7_K 153_H 1.422 0.93
196_N 217_D 1.421 0.93
17_S 71_V 1.419 0.92
85_G 88_R 1.404 0.92
197_V 212_Q 1.4 0.92
246_L 250_T 1.366 0.90
35_T 57_M 1.333 0.89
13_L 41_I 1.317 0.88
51_P 54_S 1.305 0.88
257_C 262_I 1.302 0.87
60_N 82_E 1.301 0.87
62_E 92_K 1.284 0.86
195_I 228_Y 1.265 0.85
5_I 10_I 1.25 0.84
30_Q 103_A 1.248 0.84
131_L 134_P 1.241 0.84
92_K 96_V 1.233 0.83
132_L 135_I 1.229 0.83
47_K 52_G 1.215 0.82
175_R 179_I 1.215 0.82
30_Q 66_T 1.212 0.82
195_I 224_L 1.211 0.82
199_T 212_Q 1.21 0.82
118_M 144_I 1.206 0.81
59_D 95_K 1.202 0.81
198_V 263_L 1.185 0.80
64_I 75_M 1.174 0.79
161_K 164_D 1.174 0.79
20_L 30_Q 1.168 0.78
260_F 263_L 1.168 0.78
228_Y 250_T 1.168 0.78
149_V 153_H 1.157 0.77
237_R 244_V 1.155 0.77
37_A 75_M 1.149 0.77
118_M 140_V 1.143 0.76
25_N 254_S 1.141 0.76
13_L 152_T 1.124 0.75
48_D 54_S 1.121 0.74
50_K 53_L 1.12 0.74
28_R 31_A 1.107 0.73
48_D 53_L 1.099 0.72
56_A 59_D 1.089 0.71
154_V 157_S 1.082 0.71
232_M 246_L 1.081 0.70
43_K 53_L 1.081 0.70
21_Q 29_M 1.071 0.69
41_I 45_I 1.07 0.69
6_S 44_K 1.065 0.69
116_P 188_L 1.051 0.67
20_L 71_V 1.05 0.67
241_A 245_L 1.048 0.67
14_G 149_V 1.047 0.67
189_I 229_T 1.046 0.67
7_K 248_G 1.044 0.67
195_I 263_L 1.042 0.66
202_A 205_N 1.041 0.66
147_L 151_W 1.04 0.66
105_I 146_F 1.039 0.66
5_I 220_F 1.037 0.66
205_N 208_S 1.029 0.65
213_Q 216_F 1.028 0.65
119_A 123_S 1.023 0.64
81_M 90_T 1.018 0.64
90_T 94_L 1.018 0.64
35_T 38_M 1.018 0.64
194_H 222_N 1.017 0.64
255_I 259_A 1.012 0.63
14_G 148_R 1.009 0.63
196_N 257_C 1.009 0.63
24_F 31_A 1.005 0.62
226_M 230_L 1.004 0.62
233_Y 237_R 1.003 0.62
45_I 83_E 1.002 0.62
249_V 253_L 1.001 0.62
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
2jttC20.133110.30.973Contact Map0.236
4hygA40.338410.20.973Contact Map0.418
4b19A10.11038.80.974Contact Map0.554
4hhxA10.3468.60.974Contact Map0.349
3pf6A40.21297.10.975Contact Map0.031
2lt3A10.35744.30.977Contact Map0.233
2laiA10.2894.30.977Contact Map0.14
2hgmA10.28144.10.977Contact Map0.531
1uawA10.254840.978Contact Map0.323
2jmhA10.16353.80.978Contact Map0.166

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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