| UniProt: | P42624 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12750 | ||
| Length: | 233 (227) | ||
| Sequences: | 2268 | ||
| Seq/Len: | 9.99 |
| YHAK
Paralog alert: 0.66 [within 20: 0.03] - ratio of genomes with paralogs Cluster includes: YHAK YHHW |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 173_N | 217_T | 3.308 | 1.00 | |
| 171_S | 219_V | 2.814 | 1.00 | |
| 76_R | 82_H | 2.801 | 1.00 | |
| 196_H | 219_V | 2.785 | 1.00 | |
| 72_E | 86_S | 2.481 | 1.00 | |
| 48_L | 114_R | 2.419 | 1.00 | |
| 14_D | 19_Q | 2.409 | 1.00 | |
| 66_N | 114_R | 2.337 | 1.00 | |
| 189_K | 222_S | 2.336 | 1.00 | |
| 74_E | 82_H | 2.332 | 1.00 | |
| 171_S | 217_T | 2.304 | 1.00 | |
| 187_H | 225_R | 2.27 | 1.00 | |
| 12_Q | 19_Q | 2.252 | 1.00 | |
| 89_E | 134_A | 2.16 | 1.00 | |
| 190_F | 224_L | 2.145 | 1.00 | |
| 146_P | 150_M | 2.109 | 1.00 | |
| 163_H | 225_R | 2.103 | 1.00 | |
| 202_L | 208_A | 2.065 | 1.00 | |
| 97_P | 127_N | 2.022 | 1.00 | |
| 12_Q | 21_R | 2.02 | 1.00 | |
| 61_K | 125_R | 2.019 | 1.00 | |
| 115_M | 227_L | 1.917 | 1.00 | |
| 196_H | 201_A | 1.913 | 1.00 | |
| 179_P | 230_D | 1.894 | 1.00 | |
| 176_L | 181_A | 1.887 | 1.00 | |
| 164_I | 226_A | 1.88 | 1.00 | |
| 74_E | 84_Q | 1.871 | 1.00 | |
| 15_Y | 27_G | 1.843 | 1.00 | |
| 115_M | 186_I | 1.794 | 1.00 | |
| 56_P | 100_S | 1.728 | 1.00 | |
| 189_K | 221_D | 1.716 | 1.00 | |
| 70_D | 113_T | 1.706 | 1.00 | |
| 167_D | 223_P | 1.699 | 1.00 | |
| 158_Q | 179_P | 1.688 | 1.00 | |
| 189_K | 203_T | 1.673 | 1.00 | |
| 91_L | 130_I | 1.664 | 1.00 | |
| 94_S | 126_E | 1.611 | 1.00 | |
| 131_Q | 154_Q | 1.611 | 1.00 | |
| 173_N | 215_N | 1.603 | 1.00 | |
| 189_K | 201_A | 1.591 | 1.00 | |
| 123_P | 126_E | 1.589 | 1.00 | |
| 76_R | 102_S | 1.583 | 1.00 | |
| 220_A | 223_P | 1.556 | 1.00 | |
| 196_H | 199_K | 1.547 | 1.00 | |
| 45_Q | 113_T | 1.538 | 1.00 | |
| 63_D | 94_S | 1.528 | 1.00 | |
| 78_S | 100_S | 1.519 | 1.00 | |
| 126_E | 156_R | 1.511 | 1.00 | |
| 92_L | 131_Q | 1.493 | 1.00 | |
| 168_K | 222_S | 1.474 | 1.00 | |
| 164_I | 172_A | 1.473 | 1.00 | |
| 56_P | 102_S | 1.452 | 1.00 | |
| 60_P | 125_R | 1.445 | 1.00 | |
| 167_D | 170_E | 1.441 | 1.00 | |
| 72_E | 106_L | 1.415 | 1.00 | |
| 2_I | 208_A | 1.406 | 0.99 | |
| 117_L | 229_I | 1.399 | 0.99 | |
| 190_F | 226_A | 1.392 | 0.99 | |
| 69_L | 186_I | 1.378 | 0.99 | |
| 79_E | 99_V | 1.371 | 0.99 | |
| 218_L | 226_A | 1.37 | 0.99 | |
| 70_D | 111_P | 1.354 | 0.99 | |
| 185_S | 190_F | 1.354 | 0.99 | |
| 166_L | 220_A | 1.329 | 0.99 | |
| 74_E | 106_L | 1.322 | 0.99 | |
| 183_L | 228_L | 1.298 | 0.99 | |
| 203_T | 206_D | 1.298 | 0.99 | |
| 142_L | 145_S | 1.276 | 0.99 | |
| 196_H | 221_D | 1.272 | 0.99 | |
| 145_S | 152_S | 1.26 | 0.99 | |
| 183_L | 210_I | 1.258 | 0.99 | |
| 202_L | 206_D | 1.252 | 0.99 | |
| 92_L | 144_A | 1.248 | 0.99 | |
| 70_D | 187_H | 1.236 | 0.98 | |
| 6_T | 9_Q | 1.232 | 0.98 | |
| 210_I | 216_I | 1.227 | 0.98 | |
| 64_I | 93_L | 1.218 | 0.98 | |
| 168_K | 223_P | 1.213 | 0.98 | |
| 59_Y | 101_Y | 1.212 | 0.98 | |
| 182_Y | 209_F | 1.211 | 0.98 | |
| 84_Q | 106_L | 1.198 | 0.98 | |
| 92_L | 129_L | 1.198 | 0.98 | |
| 52_A | 55_Q | 1.196 | 0.98 | |
| 123_P | 156_R | 1.19 | 0.98 | |
| 68_I | 114_R | 1.157 | 0.97 | |
| 141_Q | 146_P | 1.148 | 0.97 | |
| 60_P | 100_S | 1.139 | 0.97 | |
| 56_P | 76_R | 1.134 | 0.97 | |
| 197_E | 218_L | 1.113 | 0.96 | |
| 5_R | 34_L | 1.113 | 0.96 | |
| 221_D | 224_L | 1.112 | 0.96 | |
| 35_L | 41_R | 1.107 | 0.96 | |
| 182_Y | 229_I | 1.091 | 0.96 | |
| 39_S | 232_P | 1.089 | 0.96 | |
| 120_D | 124_Q | 1.089 | 0.96 | |
| 57_R | 101_Y | 1.083 | 0.96 | |
| 187_H | 223_P | 1.073 | 0.95 | |
| 75_Y | 130_I | 1.07 | 0.95 | |
| 86_S | 89_E | 1.052 | 0.95 | |
| 175_Q | 215_N | 1.048 | 0.94 | |
| 96_Q | 126_E | 1.028 | 0.94 | |
| 72_E | 84_Q | 1.027 | 0.94 | |
| 149_A | 160_W | 1.025 | 0.93 | |
| 20_A | 66_N | 1.024 | 0.93 | |
| 5_R | 9_Q | 1.024 | 0.93 | |
| 198_E | 213_E | 1.022 | 0.93 | |
| 75_Y | 93_L | 1.016 | 0.93 | |
| 183_L | 190_F | 1.008 | 0.93 | |
| 75_Y | 103_E | 1.007 | 0.93 | |
| 115_M | 184_Q | 1.005 | 0.93 | |
| 97_P | 128_P | 1.003 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1tq5A | 1 | 0.9785 | 100 | -0.031 | Contact Map | 0.824 |
| 2vecA | 1 | 0.9742 | 100 | 0.006 | Contact Map | 0.677 |
| 4eweA | 1 | 0.9528 | 100 | 0.164 | Contact Map | 0.728 |
| 2p17A | 1 | 0.9442 | 100 | 0.17 | Contact Map | 0.725 |
| 3o14A | 2 | 0.8627 | 99.8 | 0.704 | Contact Map | 0.582 |
| 1sq4A | 2 | 0.9185 | 99.3 | 0.782 | Contact Map | 0.608 |
| 1sefA | 1 | 0.8927 | 99.1 | 0.802 | Contact Map | 0.622 |
| 1rc6A | 2 | 0.897 | 99 | 0.814 | Contact Map | 0.619 |
| 2d40A | 4 | 0.9571 | 99 | 0.815 | Contact Map | 0.544 |
| 3h7jA | 2 | 0.8712 | 99 | 0.815 | Contact Map | 0.574 |
Sequence Conservation (Image Generated using WebLogo v3)