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YBAL - Inner membrane protein YbaL
UniProt: P39830 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12623
Length: 558 (541)
Sequences: 1755
Seq/Len: 3.24
YBAL
Paralog alert: 0.61 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: KEFB KEFC YBAL
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
485_L 502_A 4.248 1.00
321_F 338_A 2.727 1.00
485_L 509_I 2.714 1.00
422_L 433_G 2.552 1.00
487_L 499_V 2.539 1.00
141_L 146_R 2.289 1.00
503_R 511_I 2.211 1.00
423_V 485_L 2.094 1.00
502_A 509_I 2.078 1.00
313_L 379_L 2.048 1.00
105_A 109_V 2.001 1.00
306_L 310_A 1.989 1.00
212_P 265_E 1.96 1.00
98_V 102_L 1.953 1.00
269_R 273_D 1.906 1.00
419_H 483_K 1.895 0.99
499_V 529_A 1.875 0.99
298_L 371_A 1.861 0.99
100_T 122_L 1.834 0.99
503_R 530_N 1.817 0.99
515_A 521_V 1.809 0.99
309_L 375_L 1.796 0.99
104_M 121_G 1.769 0.99
311_I 315_G 1.723 0.99
19_F 233_A 1.717 0.99
38_L 42_L 1.687 0.99
123_C 352_A 1.66 0.98
479_L 506_N 1.634 0.98
31_S 134_R 1.626 0.98
517_Y 520_E 1.626 0.98
206_V 210_L 1.61 0.98
324_V 334_A 1.608 0.98
295_P 299_I 1.607 0.98
354_L 357_A 1.591 0.98
190_G 194_G 1.585 0.98
534_M 537_R 1.583 0.98
344_I 348_A 1.57 0.97
500_A 527_R 1.564 0.97
16_V 233_A 1.562 0.97
43_A 50_F 1.558 0.97
299_I 302_P 1.543 0.97
312_I 344_I 1.538 0.97
168_L 358_L 1.537 0.97
352_A 369_V 1.536 0.97
321_F 331_Q 1.535 0.97
102_L 319_A 1.535 0.97
449_S 452_R 1.519 0.97
422_L 486_I 1.518 0.97
422_L 432_L 1.514 0.97
107_S 117_G 1.512 0.96
343_Q 380_N 1.508 0.96
312_I 372_G 1.505 0.96
293_F 374_I 1.5 0.96
491_N 494_E 1.495 0.96
294_D 367_N 1.486 0.96
215_M 234_L 1.481 0.96
119_V 355_G 1.478 0.96
261_L 270_A 1.471 0.96
205_L 209_R 1.467 0.96
456_L 463_A 1.466 0.96
479_L 505_K 1.465 0.96
211_V 234_L 1.464 0.96
201_A 205_L 1.457 0.95
191_I 195_K 1.455 0.95
74_L 259_M 1.451 0.95
265_E 457_R 1.45 0.95
131_V 377_I 1.444 0.95
112_W 120_F 1.44 0.95
161_M 165_L 1.439 0.95
69_M 126_T 1.433 0.95
368_L 372_G 1.432 0.95
423_V 468_A 1.431 0.95
97_A 101_L 1.43 0.95
344_I 373_A 1.426 0.95
127_A 157_E 1.416 0.94
123_C 164_T 1.414 0.94
529_A 532_V 1.411 0.94
420_A 436_L 1.409 0.94
475_Q 480_E 1.396 0.94
496_G 520_E 1.392 0.94
487_L 498_I 1.383 0.93
324_V 329_H 1.382 0.93
122_L 164_T 1.375 0.93
418_N 483_K 1.374 0.93
104_M 118_I 1.359 0.93
101_L 105_A 1.359 0.93
149_I 329_H 1.356 0.93
194_G 198_A 1.354 0.92
104_M 108_A 1.336 0.92
487_L 495_A 1.331 0.92
362_P 365_G 1.325 0.91
401_T 407_E 1.318 0.91
146_R 333_T 1.317 0.91
356_M 366_Q 1.312 0.91
254_A 334_A 1.312 0.91
300_Q 364_A 1.307 0.91
309_L 376_S 1.306 0.91
162_V 243_V 1.305 0.91
421_L 479_L 1.305 0.91
154_L 347_F 1.3 0.90
479_L 485_L 1.299 0.90
535_G 540_A 1.297 0.90
164_T 351_L 1.292 0.90
213_W 217_R 1.286 0.90
220_A 451_T 1.284 0.90
273_D 470_N 1.282 0.89
113_S 116_T 1.278 0.89
120_F 369_V 1.268 0.89
502_A 506_N 1.268 0.89
93_I 97_A 1.266 0.89
500_A 503_R 1.26 0.88
42_L 47_T 1.259 0.88
296_L 299_I 1.256 0.88
119_V 123_C 1.253 0.88
53_D 56_L 1.25 0.88
102_L 105_A 1.249 0.88
420_A 486_I 1.247 0.88
447_E 452_R 1.243 0.87
17_L 43_A 1.243 0.87
55_K 58_P 1.239 0.87
186_A 190_G 1.238 0.87
274_T 277_L 1.238 0.87
425_Y 433_G 1.236 0.87
202_I 205_L 1.234 0.87
97_A 310_A 1.233 0.87
82_M 85_K 1.226 0.86
29_R 422_L 1.225 0.86
499_V 513_A 1.221 0.86
64_G 68_L 1.22 0.86
150_A 340_S 1.22 0.86
130_V 283_V 1.216 0.86
417_C 481_C 1.213 0.86
522_A 526_E 1.2 0.85
22_G 283_V 1.195 0.85
212_P 264_S 1.194 0.84
541_R 545_E 1.192 0.84
95_Q 347_F 1.191 0.84
537_R 541_R 1.186 0.84
542_T 546_L 1.185 0.84
231_V 270_A 1.183 0.84
300_Q 322_F 1.183 0.84
535_G 539_I 1.182 0.84
423_V 498_I 1.182 0.84
305_V 368_L 1.181 0.84
230_S 449_S 1.179 0.83
58_P 288_S 1.178 0.83
492_G 495_A 1.176 0.83
100_T 164_T 1.176 0.83
101_L 382_V 1.176 0.83
159_L 196_V 1.175 0.83
203_M 256_F 1.167 0.83
16_V 20_I 1.163 0.82
433_G 443_L 1.162 0.82
539_I 542_T 1.159 0.82
128_S 343_Q 1.157 0.82
534_M 540_A 1.156 0.82
500_A 504_A 1.155 0.82
275_L 279_D 1.154 0.82
146_R 336_T 1.151 0.81
30_I 37_L 1.15 0.81
421_L 478_H 1.149 0.81
359_N 363_Q 1.148 0.81
475_Q 505_K 1.146 0.81
523_Y 526_E 1.142 0.81
303_L 314_F 1.141 0.81
489_I 498_I 1.141 0.81
24_L 417_C 1.135 0.80
491_N 496_G 1.133 0.80
34_V 378_M 1.132 0.80
96_I 99_A 1.129 0.80
101_L 104_M 1.129 0.80
483_K 510_E 1.123 0.79
510_E 531_Q 1.122 0.79
429_G 488_T 1.122 0.79
96_I 156_V 1.122 0.79
157_E 161_M 1.12 0.79
325_R 331_Q 1.117 0.79
446_I 464_V 1.113 0.78
321_F 325_R 1.111 0.78
101_L 118_I 1.106 0.78
28_L 469_A 1.103 0.77
157_E 347_F 1.103 0.77
421_L 509_I 1.1 0.77
354_L 358_L 1.091 0.76
520_E 524_I 1.089 0.76
99_A 157_E 1.088 0.76
89_I 93_I 1.086 0.76
42_L 313_L 1.085 0.76
47_T 51_V 1.085 0.76
542_T 545_E 1.083 0.76
72_V 129_T 1.081 0.75
348_A 373_A 1.081 0.75
44_G 529_A 1.08 0.75
104_M 114_L 1.08 0.75
390_Y 393_K 1.08 0.75
501_S 506_N 1.08 0.75
218_S 227_F 1.077 0.75
151_I 374_I 1.077 0.75
107_S 112_W 1.076 0.75
13_G 17_L 1.076 0.75
489_I 495_A 1.076 0.75
306_L 315_G 1.075 0.75
99_A 103_G 1.075 0.75
227_F 266_L 1.072 0.75
445_V 461_V 1.071 0.74
68_L 337_I 1.07 0.74
132_L 341_L 1.066 0.74
101_L 485_L 1.061 0.73
339_A 383_L 1.058 0.73
453_V 463_A 1.058 0.73
430_S 459_R 1.058 0.73
486_I 512_I 1.057 0.73
299_I 318_L 1.054 0.73
23_M 229_L 1.053 0.73
537_R 540_A 1.05 0.72
300_Q 303_L 1.048 0.72
479_L 509_I 1.047 0.72
308_T 372_G 1.047 0.72
108_A 114_L 1.044 0.72
484_W 512_I 1.044 0.72
293_F 351_L 1.042 0.72
452_R 455_E 1.041 0.71
67_L 165_L 1.039 0.71
147_G 232_L 1.039 0.71
422_L 516_H 1.037 0.71
157_E 319_A 1.036 0.71
104_M 511_I 1.034 0.71
209_R 262_N 1.031 0.70
288_S 447_E 1.03 0.70
81_L 89_I 1.03 0.70
103_G 124_L 1.027 0.70
418_N 444_V 1.023 0.69
403_E 454_D 1.023 0.69
453_V 465_L 1.022 0.69
124_L 427_R 1.021 0.69
121_G 125_S 1.02 0.69
95_Q 157_E 1.02 0.69
37_L 65_V 1.019 0.69
353_G 357_A 1.019 0.69
310_A 314_F 1.018 0.69
385_A 389_K 1.014 0.69
11_I 284_L 1.013 0.68
132_L 203_M 1.013 0.68
126_T 164_T 1.013 0.68
130_V 154_L 1.012 0.68
510_E 530_N 1.012 0.68
127_A 161_M 1.011 0.68
89_I 260_V 1.011 0.68
75_H 130_V 1.01 0.68
313_L 383_L 1.009 0.68
521_V 532_V 1.005 0.68
132_L 154_L 1.004 0.67
126_T 161_M 1.003 0.67
32_P 88_A 1.003 0.67
64_G 253_G 1.002 0.67
304_A 308_T 1.002 0.67
154_L 157_E 1.002 0.67
24_L 28_L 1 0.67
77_S 263_E 1 0.67
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4bwzA10.70071000.574Contact Map0.442
3l9wA20.25991000.794Contact Map0.769
4gx0A40.45799.90.809Contact Map0.741
1zcdA20.62999.90.811Contact Map0.226
1lnqA80.449899.90.812Contact Map0.708
2aefA20.263499.90.815Contact Map0.776
3nafA10.345999.90.823Contact Map0.555
3mt5A10.258199.90.825Contact Map0.6
4g65A20.258199.90.831Contact Map0.68
3c85A40.31999.90.832Contact Map0.645
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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