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YJHG - Uncharacterized protein YjhG
UniProt: P39358 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12549
Length: 655 (549)
Sequences: 1218
Seq/Len: 2.22
YJHG
Paralog alert: 0.20 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: EDD ILVD YAGF YJHG
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
155_A 281_S 4.424 1.00
446_P 557_P 4.328 1.00
297_E 379_H 3.926 1.00
560_K 601_L 3.854 1.00
182_V 277_A 3.72 1.00
560_K 605_P 3.618 1.00
294_K 379_H 3.483 1.00
291_L 296_I 3.445 1.00
449_S 576_L 3.318 1.00
470_K 568_E 3.246 1.00
302_V 369_M 3.171 1.00
493_A 527_H 3.17 1.00
178_N 289_E 3.043 1.00
561_L 578_G 2.907 1.00
258_L 356_T 2.868 1.00
380_E 391_K 2.812 1.00
373_R 380_E 2.78 1.00
474_K 563_T 2.756 1.00
241_T 308_G 2.673 1.00
174_A 291_L 2.611 1.00
286_T 289_E 2.589 1.00
386_T 393_N 2.558 1.00
64_I 155_A 2.411 1.00
294_K 381_D 2.377 1.00
581_N 595_E 2.366 1.00
170_M 251_L 2.354 1.00
182_V 276_A 2.331 1.00
444_I 561_L 2.302 1.00
474_K 495_D 2.295 1.00
485_D 491_I 2.265 1.00
178_N 288_R 2.26 1.00
562_R 596_E 2.239 1.00
596_E 603_A 2.235 1.00
470_K 566_L 2.222 1.00
251_L 291_L 2.209 1.00
66_L 103_I 2.194 1.00
568_E 579_E 2.188 1.00
291_L 295_A 2.177 1.00
382_V 390_L 2.159 1.00
570_K 573_C 2.116 1.00
298_N 382_V 2.103 0.99
301_T 340_V 2.063 0.99
214_S 217_D 2.059 0.99
476_Y 490_K 2.013 0.99
64_I 281_S 1.994 0.99
477_L 501_G 1.988 0.99
389_T 392_E 1.986 0.99
58_E 61_R 1.959 0.99
388_S 392_E 1.937 0.99
568_E 577_H 1.929 0.99
369_M 390_L 1.919 0.99
566_L 579_E 1.917 0.99
68_S 112_A 1.909 0.99
601_L 605_P 1.901 0.99
334_I 574_R 1.885 0.99
470_K 579_E 1.882 0.99
331_D 441_V 1.87 0.99
246_A 252_A 1.862 0.98
297_E 335_R 1.859 0.98
300_M 333_W 1.857 0.98
531_I 548_V 1.839 0.98
86_H 117_D 1.823 0.98
557_P 601_L 1.821 0.98
561_L 580_V 1.819 0.98
447_E 634_W 1.815 0.98
67_L 156_V 1.791 0.98
489_D 522_L 1.779 0.98
313_L 317_P 1.77 0.98
334_I 338_K 1.763 0.98
301_T 336_I 1.751 0.98
444_I 500_I 1.726 0.97
157_I 274_A 1.723 0.97
178_N 286_T 1.7 0.97
301_T 339_R 1.689 0.97
472_V 566_L 1.673 0.96
359_A 368_V 1.673 0.96
104_K 110_P 1.666 0.96
102_V 274_A 1.654 0.96
208_F 213_L 1.646 0.96
580_V 601_L 1.636 0.96
443_N 577_H 1.628 0.96
276_A 279_N 1.616 0.95
457_D 526_K 1.607 0.95
280_L 285_I 1.569 0.94
603_A 606_S 1.562 0.94
297_E 381_D 1.534 0.94
158_G 181_T 1.514 0.93
560_K 580_V 1.512 0.93
469_H 472_V 1.509 0.93
191_P 357_V 1.502 0.93
276_A 283_K 1.488 0.92
99_A 157_I 1.487 0.92
477_L 562_R 1.478 0.92
65_L 147_I 1.473 0.92
293_D 297_E 1.47 0.92
424_S 427_Q 1.464 0.91
389_T 393_N 1.464 0.91
230_G 507_T 1.449 0.91
376_G 380_E 1.441 0.90
335_R 339_R 1.433 0.90
96_M 159_V 1.432 0.90
279_N 282_Q 1.423 0.90
228_S 264_P 1.415 0.89
174_A 251_L 1.412 0.89
101_E 104_K 1.409 0.89
304_A 336_I 1.408 0.89
231_G 507_T 1.408 0.89
475_V 561_L 1.399 0.89
241_T 312_L 1.399 0.89
147_I 156_V 1.398 0.89
172_A 177_H 1.396 0.88
562_R 607_H 1.395 0.88
475_V 578_G 1.394 0.88
438_T 574_R 1.384 0.88
474_K 492_K 1.381 0.88
388_S 393_N 1.377 0.88
451_I 571_I 1.376 0.87
581_N 596_E 1.374 0.87
478_S 481_S 1.361 0.87
293_D 326_H 1.358 0.87
505_S 554_A 1.351 0.86
130_F 510_E 1.335 0.85
66_L 156_V 1.332 0.85
208_F 215_L 1.331 0.85
190_L 262_G 1.331 0.85
373_R 391_K 1.328 0.85
158_G 183_L 1.328 0.85
438_T 572_D 1.322 0.85
64_I 103_I 1.316 0.84
56_P 223_C 1.307 0.84
125_G 514_Q 1.302 0.83
498_V 578_G 1.293 0.83
495_D 563_T 1.291 0.83
108_A 278_L 1.291 0.83
293_D 335_R 1.289 0.82
369_M 394_L 1.283 0.82
605_P 610_L 1.279 0.82
378_L 390_L 1.279 0.82
178_N 287_T 1.274 0.81
118_P 149_S 1.273 0.81
292_T 295_A 1.272 0.81
155_A 277_A 1.271 0.81
190_L 263_E 1.266 0.81
50_A 223_C 1.26 0.80
499_I 540_S 1.258 0.80
291_L 323_A 1.257 0.80
105_A 275_R 1.256 0.80
173_L 181_T 1.254 0.80
54_W 109_L 1.253 0.80
185_P 256_S 1.253 0.80
174_A 296_I 1.25 0.80
97_K 101_E 1.249 0.80
70_L 93_D 1.248 0.80
93_D 97_K 1.232 0.78
484_Y 488_H 1.226 0.78
294_K 297_E 1.225 0.78
256_S 269_I 1.225 0.78
444_I 577_H 1.224 0.78
185_P 266_W 1.224 0.78
205_G 507_T 1.222 0.78
439_F 450_V 1.217 0.77
58_E 275_R 1.209 0.76
118_P 132_S 1.208 0.76
371_H 374_S 1.207 0.76
391_K 394_L 1.205 0.76
313_L 450_V 1.205 0.76
486_I 515_V 1.201 0.76
248_G 302_V 1.195 0.75
293_D 332_D 1.195 0.75
520_K 525_G 1.185 0.74
89_H 188_A 1.183 0.74
580_V 596_E 1.18 0.74
390_L 393_N 1.17 0.73
165_G 169_T 1.167 0.73
220_R 224_K 1.164 0.73
520_K 544_C 1.162 0.72
265_V 360_F 1.156 0.72
335_R 379_H 1.152 0.71
88_G 119_C 1.151 0.71
157_I 277_A 1.151 0.71
332_D 335_R 1.147 0.71
306_F 359_A 1.144 0.71
303_H 312_L 1.142 0.70
272_A 275_R 1.136 0.70
557_P 578_G 1.134 0.70
456_I 543_A 1.133 0.70
124_Q 237_G 1.129 0.69
186_G 232_G 1.124 0.69
327_I 333_W 1.122 0.69
580_V 605_P 1.12 0.68
103_I 108_A 1.12 0.68
626_L 630_S 1.118 0.68
300_M 327_I 1.118 0.68
182_V 280_L 1.113 0.68
56_P 219_R 1.11 0.67
108_A 274_A 1.109 0.67
124_Q 235_F 1.107 0.67
472_V 495_D 1.107 0.67
67_L 114_Y 1.106 0.67
349_N 455_A 1.105 0.67
423_M 427_Q 1.103 0.67
602_N 606_S 1.103 0.67
602_N 605_P 1.103 0.67
379_H 391_K 1.102 0.67
63_G 111_Y 1.098 0.66
480_K 510_E 1.096 0.66
477_L 500_I 1.085 0.65
252_A 256_S 1.085 0.65
357_V 361_M 1.083 0.65
143_M 369_M 1.078 0.64
472_V 578_G 1.077 0.64
172_A 179_I 1.072 0.63
443_N 578_G 1.062 0.62
201_V 539_V 1.06 0.62
184_V 273_S 1.059 0.62
205_G 231_G 1.056 0.62
285_I 393_N 1.054 0.61
172_A 287_T 1.05 0.61
616_L 620_T 1.046 0.61
554_A 634_W 1.043 0.60
65_L 156_V 1.041 0.60
274_A 280_L 1.031 0.59
197_D 357_V 1.027 0.58
123_T 155_A 1.023 0.58
474_K 491_I 1.023 0.58
251_L 292_T 1.022 0.58
185_P 243_Q 1.022 0.58
202_Q 205_G 1.015 0.57
51_G 87_Q 1.015 0.57
50_A 56_P 1.014 0.57
491_I 563_T 1.012 0.57
85_L 153_A 1.01 0.57
477_L 481_S 1.008 0.56
86_H 146_L 1.008 0.56
236_L 306_F 1.007 0.56
213_L 217_D 1.006 0.56
631_G 635_T 1.004 0.56
190_L 260_P 1.003 0.56
491_I 495_D 1.002 0.56
171_M 638_I 1.001 0.56
54_W 111_Y 1.001 0.56
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2gp4A20.89471000.229Contact Map0.568
2pcnA10.213774.10.984Contact Map0.361
1j3lA60.218370.60.984Contact Map0.412
3c8oA20.2153600.985Contact Map0.351
1nxjA30.239750.30.986Contact Map0.338
1vi4A10.232137.70.987Contact Map0.317
1q5xA30.212228.40.988Contact Map0.353
1c41A100.224427.80.988Contact Map0.609
3nojA10.314519.70.989Contact Map0.412
2is8A30.207616.10.989Contact Map0.4
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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