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YJGX - Putative phosphoethanolamine transferase YjgX
UniProt: P39349 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12543
Length: 371 (318)
Sequences: 628
Seq/Len: 1.97

YJGX
Paralog alert: 0.57 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: EPTA EPTB EPTC YBIP YHBX YJGX
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
97_V 276_L 4.172 1.00
348_I 366_L 3.473 1.00
179_K 183_H 3.269 1.00
239_S 268_S 3.152 1.00
110_Y 127_F 3.031 1.00
160_V 349_F 2.905 1.00
108_S 117_T 2.87 1.00
281_G 284_R 2.655 1.00
220_E 282_I 2.533 1.00
248_N 271_K 2.498 1.00
131_Y 340_I 2.47 1.00
279_L 292_M 2.126 0.99
351_W 364_N 2.064 0.99
347_G 363_F 2.046 0.99
253_N 270_S 2.003 0.99
164_A 353_T 1.786 0.97
75_S 80_T 1.786 0.97
96_I 295_F 1.769 0.97
276_L 292_M 1.754 0.97
94_I 291_A 1.747 0.97
295_F 342_A 1.702 0.96
119_W 277_G 1.686 0.96
350_Q 357_T 1.676 0.96
218_E 221_R 1.648 0.95
107_M 236_M 1.627 0.95
123_A 277_G 1.595 0.94
234_L 279_L 1.568 0.93
73_Q 79_L 1.558 0.93
105_D 317_G 1.555 0.93
119_W 274_N 1.544 0.92
112_Y 266_L 1.537 0.92
102_V 269_I 1.524 0.92
97_V 292_M 1.509 0.91
102_V 107_M 1.498 0.91
275_F 279_L 1.494 0.91
108_S 121_N 1.473 0.90
213_K 271_K 1.468 0.90
95_V 279_L 1.467 0.90
94_I 231_I 1.452 0.89
96_I 231_I 1.424 0.88
325_I 348_I 1.415 0.87
104_R 320_S 1.398 0.86
272_L 276_L 1.391 0.86
80_T 166_K 1.378 0.85
340_I 365_P 1.374 0.85
93_T 223_L 1.362 0.84
94_I 169_Y 1.351 0.84
93_T 288_R 1.347 0.83
293_L 323_L 1.336 0.83
145_T 345_F 1.323 0.82
167_A 353_T 1.323 0.82
102_V 296_S 1.314 0.81
75_S 81_T 1.314 0.81
231_I 349_F 1.307 0.81
109_V 127_F 1.298 0.80
243_P 300_L 1.293 0.80
71_Y 158_N 1.277 0.79
291_A 331_T 1.263 0.78
108_S 270_S 1.259 0.77
220_E 224_A 1.258 0.77
115_P 121_N 1.257 0.77
102_V 239_S 1.256 0.77
97_V 279_L 1.23 0.75
116_T 266_L 1.23 0.75
103_R 272_L 1.227 0.75
61_T 65_L 1.223 0.74
103_R 298_L 1.216 0.74
171_T 186_R 1.2 0.72
307_N 313_G 1.196 0.72
55_K 58_V 1.195 0.72
291_A 325_I 1.186 0.71
325_I 354_G 1.183 0.71
213_K 278_Q 1.177 0.70
99_G 238_G 1.156 0.68
292_M 312_Y 1.155 0.68
52_R 179_K 1.14 0.67
90_L 289_H 1.139 0.67
52_R 183_H 1.132 0.66
285_R 337_S 1.131 0.66
244_C 264_C 1.129 0.66
99_G 294_Y 1.123 0.65
301_S 318_G 1.121 0.65
167_A 321_V 1.119 0.65
266_L 300_L 1.119 0.65
243_P 266_L 1.113 0.64
114_V 266_L 1.111 0.64
238_G 246_S 1.108 0.64
212_D 265_Y 1.107 0.63
99_G 235_H 1.093 0.62
72_E 229_P 1.093 0.62
360_I 364_N 1.091 0.62
219_T 234_L 1.091 0.62
215_L 275_F 1.088 0.61
218_E 223_L 1.088 0.61
130_D 339_K 1.085 0.61
112_Y 116_T 1.084 0.61
331_T 348_I 1.082 0.61
71_Y 185_T 1.081 0.61
271_K 274_N 1.079 0.60
293_L 356_C 1.077 0.60
138_T 235_H 1.074 0.60
106_Y 266_L 1.073 0.60
243_P 247_L 1.072 0.60
148_Y 347_G 1.068 0.59
87_X 333_H 1.068 0.59
217_Q 361_P 1.067 0.59
134_T 144_R 1.067 0.59
108_S 115_P 1.064 0.59
164_A 231_I 1.063 0.59
101_S 298_L 1.061 0.59
145_T 295_F 1.061 0.59
165_A 195_E 1.059 0.58
164_A 169_Y 1.056 0.58
95_V 219_T 1.053 0.58
304_D 315_V 1.053 0.58
114_V 326_T 1.053 0.58
285_R 325_I 1.052 0.58
51_L 55_K 1.049 0.57
104_R 127_F 1.046 0.57
257_Q 260_R 1.046 0.57
316_Q 320_S 1.045 0.57
219_T 223_L 1.034 0.56
54_V 58_V 1.033 0.55
100_E 138_T 1.033 0.55
69_Q 72_E 1.032 0.55
99_G 116_T 1.029 0.55
213_K 248_N 1.025 0.55
106_Y 317_G 1.023 0.54
118_P 121_N 1.023 0.54
235_H 238_G 1.021 0.54
171_T 177_Q 1.021 0.54
231_I 353_T 1.02 0.54
124_P 250_X 1.019 0.54
138_T 298_L 1.019 0.54
172_W 230_K 1.016 0.54
222_A 230_K 1.015 0.54
132_T 319_Y 1.014 0.53
211_D 292_M 1.013 0.53
63_D 70_R 1.006 0.53
100_E 212_D 1.005 0.52
142_L 178_G 1.002 0.52
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4kavA10.79511000.477Contact Map0.686
2vqrA10.83831000.497Contact Map0.615
2qzuA10.81941000.507Contact Map0.543
1p49A10.74931000.51Contact Map0.525
3b5qA20.78171000.51Contact Map0.551
1fsuA10.7521000.514Contact Map0.57
4fdiA20.74661000.515Contact Map0.586
1aukA10.74121000.516Contact Map0.517
3ed4A40.82211000.518Contact Map0.583
1hdhA20.76011000.526Contact Map0.598

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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