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OPENSEQ.org

EAMB - Cysteine/O-acetylserine efflux protein
UniProt: P38101 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12445
Length: 195 (194)
Sequences: 4741
Seq/Len: 24.44

EAMB
Paralog alert: 0.75 [within 20: 0.24] - ratio of genomes with paralogs
Cluster includes: EAMB LEUE RHTB RHTC YAHN
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
48_L 107_F 4.884 1.00
87_A 187_V 3.039 1.00
177_Q 180_I 2.849 1.00
87_A 183_A 2.781 1.00
77_W 81_A 2.623 1.00
6_L 148_L 2.606 1.00
73_H 76_S 2.554 1.00
88_W 92_T 2.536 1.00
52_I 111_F 2.445 1.00
31_A 39_S 2.384 1.00
111_F 115_F 2.165 1.00
26_L 42_V 2.114 1.00
84_V 187_V 2.096 1.00
84_V 190_A 2.067 1.00
12_Y 127_A 2.065 1.00
142_V 146_S 2.011 1.00
84_V 88_W 1.849 1.00
142_V 145_V 1.823 1.00
23_N 46_M 1.788 1.00
50_F 114_Q 1.725 1.00
153_G 157_N 1.681 1.00
91_A 180_I 1.651 1.00
184_L 188_Y 1.644 1.00
89_K 92_T 1.635 1.00
141_W 146_S 1.629 1.00
73_H 77_W 1.622 1.00
30_S 34_H 1.61 1.00
77_W 194_F 1.602 1.00
23_N 114_Q 1.594 1.00
80_A 194_F 1.59 1.00
77_W 80_A 1.57 1.00
27_A 31_A 1.541 1.00
176_R 180_I 1.532 1.00
168_Q 172_R 1.521 1.00
63_S 67_I 1.489 1.00
44_A 107_F 1.487 1.00
31_A 161_A 1.485 1.00
70_A 73_H 1.474 1.00
141_W 145_V 1.467 1.00
80_A 190_A 1.451 1.00
24_N 160_W 1.438 1.00
42_V 110_S 1.433 1.00
91_A 183_A 1.432 1.00
10_W 152_I 1.407 0.99
87_A 190_A 1.395 0.99
143_V 146_S 1.382 0.99
156_G 160_W 1.36 0.99
39_S 43_L 1.348 0.99
26_L 113_L 1.336 0.99
70_A 74_L 1.33 0.99
55_L 59_G 1.329 0.99
133_L 136_T 1.321 0.99
124_G 149_L 1.308 0.99
108_W 112_A 1.306 0.99
82_Y 86_L 1.276 0.99
141_W 144_G 1.265 0.99
177_Q 181_V 1.252 0.99
72_V 76_S 1.25 0.99
166_L 170_L 1.244 0.98
23_N 50_F 1.243 0.98
68_D 72_V 1.216 0.98
9_F 13_T 1.206 0.98
30_S 42_V 1.205 0.98
51_L 150_A 1.203 0.98
30_S 109_A 1.189 0.98
23_N 113_L 1.185 0.98
138_A 141_W 1.181 0.98
17_A 152_I 1.169 0.97
53_V 114_Q 1.165 0.97
43_L 161_A 1.164 0.97
107_F 111_F 1.138 0.97
12_Y 16_T 1.12 0.96
25_I 29_S 1.119 0.96
159_C 163_A 1.116 0.96
156_G 159_C 1.108 0.96
139_L 142_V 1.105 0.96
74_L 77_W 1.1 0.96
50_F 120_I 1.096 0.96
7_S 11_T 1.096 0.96
180_I 184_L 1.091 0.96
82_Y 85_W 1.087 0.96
167_F 171_F 1.07 0.95
36_F 162_L 1.067 0.95
11_T 15_I 1.061 0.95
116_V 125_V 1.051 0.94
166_L 169_R 1.044 0.94
178_L 182_L 1.041 0.94
48_L 111_F 1.041 0.94
151_M 155_F 1.031 0.94
65_A 68_D 1.028 0.94
85_W 89_K 1.024 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
2m67A10.37951.40.956Contact Map0.23
3j1zP20.835910.96Contact Map0.396
3udcA70.374410.96Contact Map0.537
2kv5A10.16920.90.961Contact Map0.428
2lk9A10.17950.80.962Contact Map0
2h3oA10.29740.80.962Contact Map0.268
1iijA10.17950.80.962Contact Map0.695
1cmkI10.11280.80.963Contact Map0.03
3zuxA10.52310.70.963Contact Map0.444
2wswA10.47180.70.963Contact Map0.219

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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