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OPENSEQ.org
RHTC - Threonine efflux protein
UniProt: P0AG38 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11468
Length: 206 (203)
Sequences: 4904
Seq/Len: 24.16
RHTC
Paralog alert: 0.74 [within 20: 0.23] - ratio of genomes with paralogs
Cluster includes: EAMB LEUE RHTB RHTC YAHN
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
47_C 115_F 5.136 1.00
86_G 196_A 3.115 1.00
86_G 192_G 2.811 1.00
186_W 189_G 2.778 1.00
76_V 80_L 2.543 1.00
30_A 38_A 2.527 1.00
87_Y 91_R 2.51 1.00
72_T 75_M 2.492 1.00
83_C 199_G 2.364 1.00
51_V 119_L 2.271 1.00
25_F 41_G 2.235 1.00
119_L 123_L 2.179 1.00
11_V 135_V 2.068 1.00
83_C 196_A 2.027 1.00
83_C 87_Y 1.928 1.00
22_D 45_I 1.844 1.00
160_T 164_F 1.785 1.00
49_V 122_N 1.776 1.00
90_L 189_G 1.743 1.00
193_A 197_G 1.735 1.00
176_M 180_Y 1.713 1.00
177_R 180_Y 1.704 1.00
76_V 203_I 1.7 1.00
26_V 30_A 1.692 1.00
29_T 33_R 1.665 1.00
88_Q 91_R 1.662 1.00
72_T 76_V 1.657 1.00
175_Q 179_G 1.652 1.00
174_P 178_R 1.616 1.00
79_G 203_I 1.611 1.00
79_G 199_G 1.611 1.00
90_L 192_G 1.567 1.00
22_D 122_N 1.566 1.00
76_V 79_G 1.565 1.00
43_L 115_F 1.562 1.00
171_F 174_P 1.561 1.00
5_F 155_L 1.558 1.00
185_K 189_G 1.55 1.00
9_A 159_E 1.525 1.00
62_L 66_K 1.507 1.00
41_G 118_G 1.493 1.00
69_W 72_T 1.481 1.00
69_W 73_L 1.435 1.00
173_L 177_R 1.406 0.99
25_F 121_T 1.404 0.99
112_G 116_L 1.392 0.99
38_A 42_V 1.385 0.99
86_G 199_G 1.363 0.99
174_P 180_Y 1.33 0.99
23_F 167_V 1.315 0.99
132_F 156_I 1.311 0.99
71_H 75_M 1.306 0.99
67_M 71_H 1.302 0.99
54_G 58_L 1.29 0.99
116_L 120_L 1.284 0.99
22_D 49_V 1.282 0.99
81_Y 85_M 1.265 0.99
50_M 157_I 1.261 0.99
29_T 41_G 1.253 0.99
186_W 190_F 1.227 0.98
163_W 167_V 1.194 0.98
22_D 121_T 1.187 0.98
52_W 122_N 1.179 0.98
6_L 10_M 1.177 0.98
115_F 119_L 1.175 0.98
16_L 159_E 1.163 0.97
189_G 193_A 1.159 0.97
8_V 12_H 1.152 0.97
22_D 160_T 1.146 0.97
30_A 168_A 1.141 0.97
24_F 28_Q 1.133 0.97
49_V 128_A 1.117 0.96
35_R 169_S 1.099 0.96
167_V 171_F 1.099 0.96
29_T 117_K 1.095 0.96
165_T 169_S 1.095 0.96
11_V 15_A 1.089 0.96
171_F 178_R 1.081 0.95
48_G 119_L 1.055 0.95
141_G 144_V 1.055 0.95
124_A 133_G 1.052 0.95
47_C 119_L 1.051 0.94
7_T 10_M 1.048 0.94
187_I 191_A 1.046 0.94
19_P 127_K 1.045 0.94
10_M 14_V 1.044 0.94
90_L 196_A 1.037 0.94
23_F 164_F 1.036 0.94
148_A 152_I 1.035 0.94
198_F 201_H 1.033 0.94
81_Y 84_W 1.03 0.94
196_A 199_G 1.03 0.94
64_I 67_M 1.021 0.93
84_W 88_Q 1.02 0.93
166_V 170_L 1.006 0.93
47_C 51_V 1.005 0.93
52_W 129_I 1.001 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
2cfqA10.90782.40.951Contact Map0.22
2m67A10.37861.90.953Contact Map0.259
2h3oA10.29611.70.955Contact Map0.004
3udcA70.36891.20.959Contact Map0.507
3wdoA10.45631.10.959Contact Map0.355
3j1zP20.830110.96Contact Map0.393
3o7qA10.90290.90.961Contact Map0.298
1q90G10.17960.90.962Contact Map0.751
1iijA10.16990.90.962Contact Map0.505
3s8fC10.1650.80.963Contact Map0.642
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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