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OPENSEQ.org
YIAT - Putative outer membrane protein YiaT
UniProt: P37681 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12288
Length: 246 (229)
Sequences: 671
Seq/Len: 2.93
YIAT
Paralog alert: 0.42 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: MIPA YIAT
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
101_D 178_E 4.232 1.00
58_Y 65_G 3.257 1.00
159_G 196_Y 2.7 1.00
205_I 211_L 2.635 1.00
217_Y 234_E 2.589 1.00
179_S 183_G 2.455 1.00
169_D 189_A 2.454 1.00
152_L 203_Y 2.453 1.00
77_S 112_A 2.397 1.00
100_L 184_L 2.352 1.00
79_T 110_G 2.163 1.00
103_R 170_Y 2.144 1.00
152_L 201_A 2.098 1.00
179_S 182_S 2.031 1.00
154_L 201_A 1.956 1.00
82_W 105_S 1.904 0.99
206_G 209_V 1.764 0.99
174_I 184_L 1.657 0.98
214_S 239_V 1.643 0.98
179_S 184_L 1.619 0.97
212_M 241_G 1.616 0.97
28_A 46_A 1.587 0.97
120_G 143_V 1.587 0.97
106_T 131_L 1.529 0.96
48_P 241_G 1.512 0.96
83_M 167_F 1.499 0.95
27_G 48_P 1.493 0.95
168_S 224_I 1.465 0.95
83_M 138_V 1.464 0.95
109_A 130_V 1.447 0.94
157_A 198_S 1.428 0.94
32_Y 42_E 1.414 0.93
160_V 193_W 1.41 0.93
59_V 64_L 1.396 0.93
80_A 174_I 1.384 0.92
225_T 233_N 1.377 0.92
168_S 192_A 1.376 0.92
38_R 172_Y 1.36 0.91
74_N 113_W 1.358 0.91
198_S 216_G 1.353 0.91
103_R 224_I 1.348 0.91
32_Y 44_T 1.346 0.91
172_Y 203_Y 1.338 0.90
195_P 221_P 1.324 0.90
179_S 186_S 1.305 0.89
176_E 186_S 1.289 0.88
209_V 242_V 1.274 0.87
49_L 241_G 1.23 0.85
89_P 102_K 1.229 0.85
103_R 178_E 1.228 0.85
180_R 183_G 1.226 0.84
42_E 59_V 1.22 0.84
219_E 233_N 1.218 0.84
15_F 20_T 1.211 0.83
97_M 100_L 1.209 0.83
203_Y 229_M 1.203 0.83
15_F 19_A 1.199 0.83
141_L 177_S 1.192 0.82
175_S 182_S 1.175 0.81
100_L 174_I 1.164 0.80
97_M 178_E 1.155 0.79
163_Y 192_A 1.146 0.78
209_V 244_W 1.146 0.78
163_Y 224_I 1.133 0.77
77_S 219_E 1.132 0.77
173_G 189_A 1.128 0.77
56_T 66_F 1.127 0.77
192_A 222_E 1.119 0.76
83_M 108_M 1.118 0.76
189_A 223_E 1.106 0.75
24_L 27_G 1.104 0.75
29_G 46_A 1.1 0.74
47_I 59_V 1.099 0.74
63_T 220_L 1.099 0.74
90_T 102_K 1.093 0.74
99_Q 184_L 1.092 0.74
151_R 206_G 1.089 0.73
180_R 184_L 1.086 0.73
100_L 229_M 1.08 0.72
175_S 178_E 1.076 0.72
154_L 176_E 1.069 0.71
154_L 203_Y 1.064 0.71
145_H 189_A 1.061 0.71
96_A 229_M 1.059 0.70
120_G 129_D 1.054 0.70
78_L 111_V 1.053 0.70
104_D 233_N 1.047 0.69
59_V 217_Y 1.043 0.69
192_A 224_I 1.043 0.69
75_E 114_Y 1.041 0.68
26_I 50_I 1.038 0.68
225_T 234_E 1.036 0.68
37_Y 228_P 1.034 0.68
54_G 110_G 1.033 0.68
99_Q 229_M 1.033 0.68
106_T 133_N 1.033 0.68
55_D 114_Y 1.03 0.67
34_E 42_E 1.026 0.67
124_A 139_G 1.016 0.66
31_A 47_I 1.013 0.65
139_G 162_Y 1.012 0.65
146_K 155_T 1.01 0.65
76_L 215_A 1.009 0.65
101_D 175_S 1.006 0.65
60_R 63_T 1.001 0.64
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2x27X10.691198.20.842Contact Map0.543
3nb3A30.75298.20.844Contact Map0.718
2k0lA10.7724980.852Contact Map0.349
2f1vA60.68797.20.872Contact Map0.613
1qjpA10.642397.10.875Contact Map0.778
2lhfA10.658596.90.878Contact Map0.563
1p4tA10.605796.70.88Contact Map0.753
3qraA10.5772960.889Contact Map0.654
2jmmA10.5772960.889Contact Map0.497
1ormA10.56195.50.893Contact Map0.281
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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