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OPENSEQ.org
MIPA - MltA-interacting protein
UniProt: P0A908 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13492
Length: 248 (232)
Sequences: 675
Seq/Len: 2.91
MIPA
Paralog alert: 0.41 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: MIPA YIAT
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
103_D 180_E 4.257 1.00
60_W 67_G 3.261 1.00
161_G 198_Y 2.713 1.00
207_F 213_V 2.615 1.00
154_L 205_Y 2.589 1.00
219_Y 236_W 2.497 1.00
181_S 185_G 2.406 1.00
171_E 191_P 2.337 1.00
105_R 172_Y 2.316 1.00
79_S 114_S 2.264 1.00
102_L 186_L 2.193 1.00
81_T 112_G 2.104 1.00
154_L 203_A 2.096 1.00
156_V 203_A 2.052 1.00
84_W 107_S 2.013 1.00
181_S 184_S 1.938 0.99
29_G 36_E 1.847 0.99
91_A 104_D 1.831 0.99
208_L 211_W 1.821 0.99
108_T 133_L 1.718 0.98
50_P 243_G 1.671 0.98
30_A 34_V 1.615 0.97
111_A 132_T 1.597 0.97
29_G 38_P 1.575 0.97
216_T 241_S 1.565 0.97
176_V 186_L 1.557 0.96
214_Y 243_G 1.534 0.96
170_N 226_V 1.499 0.95
105_R 226_V 1.484 0.95
162_V 195_W 1.462 0.95
181_S 186_L 1.462 0.95
159_G 200_E 1.44 0.94
29_G 54_Y 1.431 0.94
122_G 145_W 1.405 0.93
85_S 140_V 1.404 0.93
181_S 188_G 1.386 0.92
85_S 169_Q 1.383 0.92
227_T 235_S 1.376 0.92
76_D 115_Y 1.373 0.92
200_E 218_R 1.36 0.91
170_N 194_S 1.325 0.90
105_R 180_E 1.293 0.88
17_A 21_H 1.285 0.88
131_D 135_N 1.272 0.87
174_Y 205_Y 1.269 0.87
27_S 174_Y 1.258 0.86
61_F 66_G 1.249 0.86
197_P 223_S 1.241 0.85
54_Y 112_G 1.241 0.85
102_L 176_V 1.239 0.85
16_S 19_V 1.223 0.84
29_G 33_G 1.222 0.84
99_M 180_E 1.218 0.84
165_N 226_V 1.204 0.83
39_Y 50_P 1.203 0.83
20_A 23_E 1.193 0.82
92_K 95_G 1.19 0.82
211_W 244_I 1.189 0.82
46_V 173_Y 1.189 0.82
51_V 243_G 1.182 0.81
16_S 21_H 1.177 0.81
85_S 110_M 1.175 0.81
83_Y 173_Y 1.17 0.80
194_S 224_D 1.164 0.80
205_Y 231_M 1.157 0.79
165_N 194_S 1.153 0.79
182_A 185_G 1.151 0.79
58_N 68_Y 1.15 0.79
211_W 246_Y 1.143 0.78
31_G 143_M 1.138 0.78
182_A 186_L 1.136 0.77
122_G 131_D 1.133 0.77
221_R 235_S 1.129 0.77
61_F 219_Y 1.124 0.76
40_K 174_Y 1.124 0.76
32_V 48_P 1.122 0.76
143_M 179_K 1.121 0.76
105_R 165_N 1.117 0.76
178_R 188_G 1.115 0.76
194_S 226_V 1.112 0.75
27_S 53_N 1.108 0.75
147_Y 191_P 1.099 0.74
98_Q 231_M 1.096 0.74
128_L 139_I 1.095 0.74
56_G 112_G 1.089 0.73
175_G 191_P 1.08 0.72
66_G 126_T 1.078 0.72
17_A 20_A 1.074 0.72
108_T 135_N 1.072 0.71
37_H 180_E 1.071 0.71
99_M 102_L 1.061 0.70
146_L 159_G 1.057 0.70
137_N 234_K 1.055 0.70
177_S 184_S 1.053 0.70
177_S 180_E 1.053 0.70
105_R 194_S 1.053 0.70
39_Y 230_P 1.028 0.67
93_D 104_D 1.018 0.66
16_S 20_A 1.017 0.66
54_Y 197_P 1.015 0.65
38_P 88_Y 1.013 0.65
227_T 236_W 1.011 0.65
215_G 244_I 1.007 0.65
30_A 245_T 1.006 0.64
79_S 221_R 1.004 0.64
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3nb3A30.758198.50.825Contact Map0.679
2x27X10.681598.20.841Contact Map0.546
2k0lA10.770297.40.866Contact Map0.338
2f1vA60.677497.20.871Contact Map0.608
1qjpA10.637196.90.876Contact Map0.795
2lhfA10.649296.90.877Contact Map0.583
1p4tA10.600896.50.882Contact Map0.77
2jmmA10.572695.90.888Contact Map0.462
3qraA10.572695.40.893Contact Map0.676
1ormA10.556594.30.899Contact Map0.287
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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